KEGG ORTHOLOGY: K24496

ORTHOLOGY: K24496

Entry

K24496                      KO

Symbol

NPHS1

Name

nephron

Disease

H01657

Nephrotic syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K24496  NPHS1; nephron
Domain-containing proteins not elsewhere classified [BR:ko04990]
Fibronectin (FN) domain-containing proteins
  Fibronectin type III domain-containing proteins
   K24496  NPHS1; nephron

Genes

HSA:	4868(NPHS1)

PTR:	468841(NPHS1)

PPS:	100982087(NPHS1)

GGO:	101123744(NPHS1)

PON:	100449007(NPHS1)

NLE:	100583583(NPHS1)

HMH:	116479636(NPHS1)

MCC:	106996059 114670312 114675763 718929(NPHS1)

MCF:	102120468 107127882(NPHS1)

MTHB:

126929262 126941946

MNI:	105495497(NPHS1)

CSAB:

103234542(NPHS1)

CATY:

105578195(NPHS1)

PANU:

101017014 101021992(NPHS1)

MLEU:

105543102(NPHS1)

RRO:	104666694(NPHS1) 104666999

TFN:	117087158 117092380(NPHS1) 117093538

PTEH:

113222610(NPHS1)

CANG:

105516229(NPHS1)

CJC:	100392294(NPHS1)

SBQ:	101052075(NPHS1)

CIMI:

108298521(NPHS1)

CSYR:

103249684(NPHS1)

MMUR:

105876904(NPHS1)

LCAT:

123624453(NPHS1)

PCOQ:

105816166(NPHS1)

OGA:	105887613(NPHS1)

MMU:	54631(Nphs1)

MCAL:

110297673(Nphs1)

MPAH:

110327198(Nphs1)

RNO:	64563(Nphs1)

MCOC:

116100440(Nphs1)

ANU:	117717874(Nphs1)

MUN:	110550893(Nphs1)

CGE:	100773617(Nphs1)

MAUA:

101839599(Nphs1)

PROB:

127238437(Nphs1)

PLEU:

114681669(Nphs1)

MORG:

121449639(Nphs1)

MFOT:

126486733

AAMP:

119821106(Nphs1)

NGI:	103729942(Nphs1)

HGL:	101705086(Nphs1)

CPOC:

100713185(Nphs1)

CCAN:

109689282(Nphs1)

DORD:

105993124(Nphs1)

DSP:	122097465(Nphs1)

PLOP:

125368010(Nphs1)

NCAR:

124966336

MMMA:

107151748(Nphs1)

OCU:

100354996

OPI:	101536537(NPHS1)

TUP:	102478645(NPHS1)

GVR:	103592817(NPHS1)

CFA:	484571(NPHS1)

CLUD:

112643524(NPHS1)

VVP:	112928471(NPHS1)

VLG:	121480173(NPHS1)

NPO:	129500428(NPHS1)

AML:	100466832(NPHS1)

UMR:	103682524(NPHS1)

UAH:	113244761(NPHS1)

UAR:	123793903(NPHS1)

ELK:

111161575

LLV:

125088369

MPUF:

101671776(NPHS1)

MNP:	132005317(NPHS1)

MLK:	131818541(NPHS1)

NVS:	122911570(NPHS1)

ORO:	101380280(NPHS1)

EJU:	114224362(NPHS1)

ZCA:	113935552(NPHS1)

MLX:	118022791(NPHS1)

NSU:	110590089(NPHS1)

LWW:	102733797(NPHS1)

FCA:	101101018(NPHS1)

PYU:	121011542(NPHS1)

PCOO:

112851007(NPHS1)

PBG:	122495066(NPHS1)

PVIV:

125153622(NPHS1)

LRUF:

124511942

PTG:	102964217(NPHS1)

PPAD:

109251504(NPHS1)

PUC:

125915797

AJU:

106974743

HHV:	120243514(NPHS1)

BTA:	519706(NPHS1)

BOM:	102279035(NPHS1)

BIU:	109572326(NPHS1)

BBUB:

102408360(NPHS1)

BBIS:

104995260(NPHS1)

CHX:	102173409(NPHS1)

OAS:	101115895(NPHS1)

BTAX:

128063628(NPHS1)

ODA:	120872606(NPHS1)

CCAD:

122421380(NPHS1)

MBEZ:

129546061(NPHS1)

SSC:	100622946(NPHS1)

CFR:	102519807(NPHS1)

CBAI:

105065104(NPHS1)

CDK:	105088062(NPHS1)

VPC:	102539309(NPHS1)

BACU:

103020804(NPHS1)

BMUS:

118884799(NPHS1)

LVE:	103076086(NPHS1)

OOR:	101287446(NPHS1)

DLE:	111180548(NPHS1)

PCAD:

102989131(NPHS1)

PSIU:

116744555(NPHS1)

NASI:

112392226(NPHS1)

ECB:	100147013(NPHS1)

EPZ:	103566805(NPHS1)

EAI:	106829153(NPHS1)

MYB:	102242721(NPHS1)

MYD:	102760743(NPHS1)

MMYO:

118674816(NPHS1)

MLF:	102420476(NPHS1)

PKL:	118720610(NPHS1)

EFUS:

103284520(NPHS1)

MNA:	107543370(NPHS1)

DRO:	112320159(NPHS1)

SHON:

118982560(NPHS1)

AJM:	119044200(NPHS1)

PDIC:

114511709(NPHS1)

PHAS:

123823773(NPHS1)

MMF:	118638955(NPHS1)

PPAM:

129083103(NPHS1)

HAI:	109372013(NPHS1)

RFQ:	117034920(NPHS1)

PALE:

102896148(NPHS1)

PGIG:

120592439(NPHS1)

PVP:	105306656(NPHS1)

RAY:	107497663(NPHS1)

MJV:	108401531(NPHS1)

TOD:	119250255(NPHS1)

SARA:

101538761(NPHS1)

SETR:

126028492(NPHS1)

LAV:	100665179(NPHS1)

TMU:

101345161

ETF:	101660203(NPHS1)

DNM:	101430106(NPHS1)

MDO:	100016152(NPHS1)

GAS:	123240076(NPHS1)

SHR:	100927411(NPHS1)

AFZ:

127556063

PCW:	110201361(NPHS1)

OAA:	103168942(NPHS1)

PRUF:

121364113

OMA:	130262705(NPHS1)

RTD:	128903915(NPHS1)

ASN:	102381936(NPHS1)

AMJ:	102572209(NPHS1)

PSS:	102455361(NPHS1)

CMY:	102930154(NPHS1)

DCC:	119847614(NPHS1)

CPIC:

101948649(NPHS1)

TST:	117869828(NPHS1)

CABI:

116818447(NPHS1)

MRV:	120390612(NPHS1)

ACS:	100555423(nphs1)

ASAO:

132780663(NPHS1)

PVT:	110070504(NPHS1)

SUND:

121915498(NPHS1)

PBI:	103068118(NPHS1)

PMUR:

107288354(NPHS1)

CTIG:

120300153(NPHS1)

TSR:	106555575(NPHS1)

PGUT:

117669318(NPHS1)

APRI:

131204718(NPHS1)

PTEX:

113437674(NPHS1)

NSS:	113427305(NPHS1)

VKO:	123026028(NPHS1)

PMUA:

114602891 114602892(NPHS1)

PRAF:

128418573(NPHS1)

ZVI:	118086747(NPHS1)

HCG:	128333075(NPHS1)

GJA:	107108173(NPHS1)

STOW:

125435440(NPHS1)

EMC:	129342934(NPHS1)

XLA:	734213(nphs1.S)

XTR:	100494620(nphs1)

NPR:	108798923(NPHS1)

RTEM:

120916228(NPHS1)

BBUF:

120993721(NPHS1)

BGAR:

122927083(NPHS1)

MUO:	115476625(NPHS1)

GSH:	117345796(NPHS1)

DRE:	692352(nphs1)

SRX:

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122359595(nphs1)

LROH:

127176997(nphs1)

OMC:	131520417(nphs1)

PPRM:

120478714(nphs1)

RKG:	130077930(nphs1)

MAMB:

125249535(nphs1)

CIDE:

127495664

MASI:

127429843

TROS:

130564941(nphs1)

TDW:	130429251(nphs1)

MANU:

129438367(nphs1)

IPU:

108278108

IFU:	128621512(nphs1)

PHYP:

113539257(nphs1)

SMEO:

124394122(nphs1)

TFD:	113642327(nphs1)

TVC:	132858373(nphs1)

AMEX:

103038279(nphs1)

CMAO:

118804681(nphs1)

EEE:	113588822(nphs1)

CHAR:

105901271(nphs1)

TRU:	101074785(nphs1)

TFS:	130532257(nphs1)

TNG:	GSTEN00034184G001

LCO:	104925516(nphs1)

NCC:	104961402(nphs1)

TBEN:

117480687(nphs1)

CGOB:

115021056(nphs1)

PGEO:

117460423(nphs1)

GACU:

117554006(nphs1)

EMAC:

134861422(nphs1)

ELY:	117265501(nphs1)

EFO:	125893720(nphs1)

PLEP:

121945398(nphs1)

SLUC:

116049353(nphs1)

ECRA:

117946585(nphs1)

ESP:	116691004(nphs1)

PFLV:

114556964(nphs1)

GAT:	120810315(nphs1)

PPUG:

119198047(nphs1)

AFB:	129110176(nphs1)

CLUM:

117745602(nphs1)

PSWI:

130213234(nphs1)

MSAM:

119897796(nphs1)

SCHU:

122881422(nphs1)

CUD:	121513527(nphs1)

ALAT:

119006537(nphs1)

MZE:	101478627(nphs1)

ONL:	100701764(nphs1)

OAU:	116319812(nphs1)

OLA:	101155460(nphs1)

OML:	112143574(nphs1)

CSAI:

133440607(nphs1)

XMA:	102228961(nphs1)

XCO:	114139282(nphs1)

XHE:	116715222(nphs1)

PRET:

103478528(nphs1)

PFOR:

103143095(nphs1)

PLAI:

106945865(nphs1)

PMEI:

106927182(nphs1)

GAF:	122831098(nphs1)

PPRL:

129371341(nphs1)

CVG:	107086093(nphs1)

CTUL:

119771537(nphs1)

GMU:	124863568(nphs1)

NFU:	107378623(nphs1)

KMR:	108241976(nphs1)

ALIM:

106517710(nphs1)

AOCE:

111577065(nphs1)

MCEP:

125015857(nphs1)

CSEM:

103388504(nphs1)

POV:	109633030(nphs1)

SSEN:

122775190(nphs1)

HHIP:

117776215(nphs1)

HSP:	118113856(nphs1)

SMAU:

118312825(nphs1)

LCF:

108890767

SDU:	111234037(nphs1)

SLAL:

111664918(nphs1)

XGL:	120784504(nphs1)

BPEC:

110171498(nphs1)

MALB:

109971696(nphs1)

BSPL:

114843411(nphs1)

SJO:	128366816(nphs1)

SASA:

106605624

STRU:

115182907

OTW:	112245877(nphs1)

OMY:	110538442(nphs1)

OGO:	123996968(nphs1)

ONE:

115140880

OKI:	109901663(nphs1)

OKE:	118364086(nphs1)

SALP:

112067951

SNH:	120047219(nphs1)

CCLU:

121562834 123492837

ELS:	105019153(nphs1)

SFM:	108930312(nphs1)

PKI:

111841096

AANG:

118219770(nphs1)

LOC:	102690772(nphs1)

PSPA:

121299234(nphs1) 121301254 121320771

ARUT:

117433768 117962692

LCM:	102357007(NPHS1)

PMRN:

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

DME:	Dmel_CG33141(sns)

DER:

6542389

DSE:

6608236

DSI:	Dsimw501_GD10605(Dsim_GD10605)

DYA:	Dyak_GE19230

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI18925

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:	1272555 4397681

ACOZ:

120956221 120956222 120956355

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ001305

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:	129000363 129004623

PHU:	Phum_PHUM068980

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_305049

DMK:

116915605

DPZ:

124314606

PVM:	113802662 113813958

PJA:	122249449 122251254 122252771 122254215 122254589 122256064 122259782 122259817 122260242 122262065 122262562 122267895

PCHN:

125033351 125045353 125045717 125047951

PMOO:

119577630 119595157 119597122

HAME:

121854498 121863150 121863387 121865842 121867769 121874860 121879722

PCLA:

123755806 123762750 123766121 123766211 123769483 123770509 123771721 123774448 123774449

CQD:	128688793 128693143 128693160 128696637

PTRU:

123501671 123502034 123505024 123506073 123507096 123512239 123520665 123520757 123520837

ESN:	126994337 127004947 127008756

MNZ:	135196169 135198010 135198097 135201267 135209819 135212176 135214186 135226583 135227091

HAZT:

108664788 108679880 108682113

EAF:	111704569 111711354

LSM:	121117533 121117756

TCF:	131883444 131883887

PPOI:

119093960 119102923 119102940 119105439

ISC:

8042097

DSV:	119455428 119457078

RSAN:

119376741 119393097 119394371

RMP:	119171604 119172902

VDE:	111249008 111250378 111251006

VJA:	111259907 111264601 111273817

TUT:

107371656

DPTE:

113788944

DFR:	124490925 124500389

CSCU:

111635045

PTEP:

107441037 107443592 107449764 107454481

ABRU:

129958649 129966056 129966074 129968147 129968766 129976732 129989305

UDV:	129218240 129228432 129228493 129228672 129229565

SDM:	118184280 118186316 118191999 118195504 118197468

LPOL:

106457250 106457828 106457838 106460984 106461973 106466744 106470423 106476276 111084557 111086920

CEL:	CELE_C26G2.1(syg-2)

CBR:	CBG_07568(Cbr-syg-2)

CRQ:	GCK72_025659

NAI:	NECAME_07285

BMY:	BM_BM2413(Bma-syg-2)

LOA:	LOAG_01148

TSP:

PVUL:

PCAN:

BGT:

GAE:

HRF:	124116188 124119607 124125796 124126441

HRJ:	124255657 124267484 124271926 124274412

CRG:

105325024

CVN:

111126376

CANU:

128192460

OED:	125678729 130046346 130048680 130048686 130048696 130051329

MYI:

110464274

PMAX:

117319382 117340235

MMER:

123559742 123560091

RPHI:

132732983 132736976 132754476

DPOL:

127860780 127873643

OBI:

106873723

OSN:	115212345 115220440

LAK:

106151486

SMM:	Smp_130070

OVI:	T265_02206

EGL:

EGR_09148

» show all

Reference

PMID:9660941

Authors

Kestila M, Lenkkeri U, Mannikko M, Lamerdin J, McCready P, Putaala H, Ruotsalainen V, Morita T, Nissinen M, Herva R, Kashtan CE, Peltonen L, Holmberg C, Olsen A, Tryggvason K

Title

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome.

Journal

Mol Cell 1:575-82 (1998)
DOI:10.1016/s1097-2765(00)80057-x

Sequence

[hsa:4868]

LinkDB

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