Bacillus subtilis subsp. spizizenii TU-B-10: GYO_0678
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Entry
GYO_0678 CDS
T01635
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
bst
Bacillus subtilis subsp. spizizenii TU-B-10
Pathway
bst00300
Lysine biosynthesis
bst00550
Peptidoglycan biosynthesis
bst01100
Metabolic pathways
bst01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
bst00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GYO_0678
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GYO_0678
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GYO_0678
Enzymes [BR:
bst01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GYO_0678
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
VMAP-C
Motif
Other DBs
NCBI-ProteinID:
AEP85385
UniProt:
G4NU25
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All DBs
Position
626397..627770
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AA seq
457 aa
AA seq
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MIKRTVKNIAEMVKGTLTNPQYEQTVIHGVATDTRKLEQQQLFIPLKGEHFNGHTFVPQA
FEAGVAAVLWDRSEPNPPENQAVILVDDTLSALQQLAKAYLQELGTRVIGVTGSNGKTTT
KDMIHAVLGTRYRVHKTGGNFNNHIGLPLTVLAMPEDTEIAVLEMGMSAKGEIDLLSRLA
NPDAAVITNIGESHMQDLGSREGIAEAKLEIINGLKEDGVLIYIGDEPLLQNAYSCQTKT
YGTGAHNDYLLQDVSQSEEGTHFTIKGMEKTFFIPILGKHNVMNAMAAIAAGAYFGITPE
DAAKGLSGLKVTGMRLELIKTDSGISIINDAYNASPTSMKAAILLTESLEGYGKKMLVLG
DMLELGDLEETFHKECGAVISPEKIDRVFTYGKLGAFIAEGALKHFEKERVSHYTEKKDL
LQAVKENASKGDLILFKASRGMKLEEIVKDLIESPLS
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
ttgattaaacgaacagtaaagaacattgcggagatggtcaaaggcacactgacaaatccg
caatatgaacaaacagtcattcatggagtggcaactgatacaagaaaactggaacaacag
cagcttttcatcccgctgaaaggggaacatttcaacggccacacttttgtgccgcaggct
tttgaagccggtgtagcggccgttctttgggatcggtcagaaccaaacccgcccgagaat
caagccgtgatcttagtggacgacaccctttccgctcttcagcagcttgcaaaagcttat
ttgcaggagcttggcacccgtgtcatcggggtaactggaagcaatggcaaaacgacaacg
aaagatatgattcacgccgtcctgggaacccgataccgtgtccacaaaacaggaggaaac
ttcaataatcacatcggtctgccgctgacggttttagccatgcctgaagatacggagatc
gctgtattggagatgggaatgagcgccaaaggagaaattgatcttctgtcccgcctggca
aacccggatgctgcagtaattacgaatatcggcgaatcccacatgcaagaccttggctca
agagaaggtatcgcggaggcgaagcttgaaatcattaatgggctaaaagaagacggggtg
ctgatttatatcggagacgaaccgctccttcaaaatgcatacagctgccagacgaaaacg
tacggtacgggagcgcataatgattatctgcttcaggatgtcagccagagcgaggaagga
acccattttacaatcaaagggatggaaaaaacgttttttattccgatacttggcaagcac
aatgtcatgaacgccatggctgcgattgctgcaggggcttatttcggcatcacgcctgag
gatgcggcaaaaggactgagcggtctaaaggtaactggcatgagacttgaactcatcaaa
acagacagcggcatttcgataatcaatgacgcttataatgccagtccgacttccatgaag
gctgcgattctattgacagaaagtcttgaaggctacgggaaaaaaatgctcgtgctcggc
gatatgcttgaactcggcgatcttgaagaaacattccataaagagtgcggcgctgtgatc
agccctgagaaaattgaccgcgtctttacgtacggaaaactgggagcttttatcgcggaa
ggcgcactgaaacactttgagaaagaacgcgtcagccattacactgagaaaaaagatctc
ctccaagctgtgaaggaaaacgcgtcaaaaggagatttaattttattcaaagcgtccaga
ggtatgaagcttgaagaaatcgttaaagatttaatagagagcccgctttcgtaa
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