Equus caballus (horse): 100072339
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Entry
100072339 CDS
T01058
Symbol
ROCK2
Name
(RefSeq) rho-associated protein kinase 2 isoform X1
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04062
Chemokine signaling pathway
ecb04071
Sphingolipid signaling pathway
ecb04270
Vascular smooth muscle contraction
ecb04310
Wnt signaling pathway
ecb04360
Axon guidance
ecb04510
Focal adhesion
ecb04520
Adherens junction
ecb04530
Tight junction
ecb04611
Platelet activation
ecb04670
Leukocyte transendothelial migration
ecb04810
Regulation of actin cytoskeleton
ecb04921
Oxytocin signaling pathway
ecb05132
Salmonella infection
ecb05135
Yersinia infection
ecb05163
Human cytomegalovirus infection
ecb05200
Pathways in cancer
ecb05205
Proteoglycans in cancer
ecb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100072339 (ROCK2)
04071 Sphingolipid signaling pathway
100072339 (ROCK2)
04024 cAMP signaling pathway
100072339 (ROCK2)
04022 cGMP-PKG signaling pathway
100072339 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100072339 (ROCK2)
04520 Adherens junction
100072339 (ROCK2)
04530 Tight junction
100072339 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100072339 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100072339 (ROCK2)
04670 Leukocyte transendothelial migration
100072339 (ROCK2)
04062 Chemokine signaling pathway
100072339 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
100072339 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100072339 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
100072339 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100072339 (ROCK2)
05205 Proteoglycans in cancer
100072339 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100072339 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
100072339 (ROCK2)
05135 Yersinia infection
100072339 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100072339 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100072339 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ecb03036
]
100072339 (ROCK2)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100072339 (ROCK2)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
100072339 (ROCK2)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100072339 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
APH
Pkinase_C
Irp3-like_C
Motif
Other DBs
NCBI-GeneID:
100072339
NCBI-ProteinID:
XP_023475292
Ensembl:
ENSECAG00000009872
VGNC:
22497
LinkDB
All DBs
Position
15:83560370..83721757
Genome browser
AA seq
1512 aa
AA seq
DB search
MSRPAPTGKMPGAPEAVPGDGAGASRQRKLEALIRDPRSPINVESLLTATPDYQEGFWEH
TVKIYVLIVPFKIPQILNLEASCPKDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKI
RGLQMKAEDYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERD
IMAFANSPWVVQLFCAFQDDKYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLAL
DAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVL
KSQGGDGYYGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEIS
KHAKNLICAFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSS
NFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRENDSIQSRKNEES
QEIQKKLDTLEEHLSTEMQAKEELEQKCKSVNIRLEKAAKELEEEITLRKNVESALRQLE
REKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNSQISTEKVNQLQR
QLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFIN
LQSVLESERRDRTHGSEIINDLQGRISGLEEDLKNGKILLAKVELEKRQLQERFTDLEKE
KNNMEIDMTYQLKVIQQTLEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLE
ERTLKQKVENLLLEAEKRCSILDCDFKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQK
RCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMSLEKQNAELRKERQDADGQMKEL
QDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKELQQKKQELQDERDSLAAQLEITLTKA
DSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTLTSDV
ANLANEKEELNNKLKDAQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKLAEIM
NRKEPVKRGSDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIR
IELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGSGPGDAEADDGFPVHITQSHTMESMS
FTYQRSSTSLNIATKPSSSHMLLDSDSDSEEESLPYLPISSEPNGTESRLEGWLSLPVRN
NTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPYMVLDIDKLFHVRPVTQTDVYRADAKE
IPRIFQILYANEGESKKEQEFPVEPVGEKSNYICHKGHEFIPTLYHFPTNCEACMKPLWH
MFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKVYYDISTAKNLLLLANSTEEQQKWVSR
LVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRRPSRQLAPNKPRLLDLAFKDWDWSFDD
IDGDDDGDVFDF
NT seq
4539 nt
NT seq
+upstream
nt +downstream
nt
atgagccggcccgcgccgacggggaaaatgcccggcgcccccgaggccgtgcccggggac
ggggcgggcgcgagccgccagaggaagctggaggcgctcatccgagacccgcgctcgccc
atcaacgtggagagcctgctgactgctaccccagactaccaagagggtttttgggaacat
actgtaaagatttatgtacttattgtaccattcaaaatcccccaaattctgaatttggaa
gcatcttgccccaaggatggcttaaattctttggtccttgatttggattttcctgctttg
aggaaaaataagaatatagataatttcttaaatagatatgagaaaattgtgaaaaaaatc
agaggtctacagatgaaggcagaagactatgatgttgtaaaagttattggaagaggtgct
tttggtgaagtccagttggttcgtcacaaggcatcacagaaggtttatgctatgaagctt
cttagtaagtttgaaatgataaagagatcagattctgcttttttctgggaagaaagagat
attatggcctttgccaacagtccctgggtggttcagctcttttgtgcctttcaagatgat
aaatatctgtacatggtaatggaatacatgcctggtggagaccttgtaaatcttatgagt
aactatgatgtacctgaaaaatgggccaagttttatactgctgaagttgttcttgctctg
gatgccatacactccatgggtttaattcacagagatgtgaagcctgacaacatgctcttg
gataaacatggacatctaaaattagcagattttggcacatgtatgaagatggatgaaaca
ggcatggtgcattgtgatacagcagttggaacacctgattatatatcacctgaggttctg
aaatcacaagggggtgatggttactatgggagagaatgtgattggtggtctgtgggtgtt
ttcctttttgagatgctagtgggtgatactccattttatgcagattcgcttgtaggaaca
tacagcaaaattatggatcataaaaactcactatgtttccctgaagatgcagaaatttct
aaacatgcgaagaatctcatctgtgccttcttaacagatagggaggtacgacttgggaga
aatggggtagaagaaatcaaacaacatcctttctttaagaatgatcaatggaattgggat
aacataagagagacggcagctcctgtagtacctgaactcagcagtgacatagatagcagc
aattttgacgacattgaagatgataaaggagatgtagaaaccttcccaattcctaaagcg
tttgtgggaaatcagctgcctttcataggatttacctactatagagaaaatttgttatta
agtgactctccatcttgtagagaaaatgattcaatacaatcaaggaaaaatgaagagagt
caagagattcagaaaaaactagacacattagaagaacaccttagcactgagatgcaagcc
aaagaggaactagagcagaagtgcaaatctgttaatattcgcctagagaaggcagcaaag
gagctagaagaagagattaccttaaggaaaaatgtggaatcagcattgagacaattagaa
agagaaaaagcacttcttcagcacaaaaatgcagaatatcagcggaaagctgatcatgaa
gcagacaagaaacgaaatttggaaaatgatgttaacagtttaaaagatcaacttgaagat
ttgaaaaaaagaaatcagaactctcaaatatctacagagaaagtgaatcaactccagaga
caactggatgaaaccaatgctttgctgcggacagaatctgatactgcagcccggttaaga
aaaacccaggcagaaagttcaaagcagattcagcagctggaatcgaacaatagagatcta
caagataaaaattgcctgctggagactgccaagttaaaacttgaaaaggaatttatcaat
cttcagtcagttctagaatctgaaaggagggaccgaacccatggatcagagataattaat
gatttacaaggtagaatatctggcctagaagaagatttaaagaatggcaaaatcttatta
gcaaaagtagagctggagaagagacaactacaggagagatttactgatttggaaaaggaa
aagaataacatggaaatagatatgacataccaactaaaagttatacagcagaccttagaa
caagaagaagctgaacataaggctacaaaagcacggctggcagataaaaataagatttat
gaatccattgaagaagctaaatcggaagccatgaaagaaatggagaaaaagctcttggag
gaaaggactttaaaacagaaagtggagaacctgttactagaagctgagaaaagatgctct
atattagactgtgacttcaaacagtcacagcagaaaatcaatgaactccttaaacagaaa
gatgtgctaaatgaggatgttagaaacttgacattaaaaatagaacaggaaactcagaag
cgctgcctcacacaaaatgacttgaagatgcaaacacagcaagttaacacactaaagatg
tcagaaaagcagttaaaacaagagaataatcacctcatggaaatgaaaatgagcttggaa
aaacagaatgctgaacttcgaaaagagcgtcaagatgcggatgggcaaatgaaagagctc
caagatcagcttgaagcagagcagtatttctcaaccctctataaaacacaggttagggaa
cttaaagaagaatgtgaagaaaagaccaaactttgtaaagaattacagcagaagaagcag
gaattacaggatgaaagggactccttggctgctcaactggagatcaccttgaccaaagca
gattctgagcagctggctcgttcaattgctgaagaacaatattctgatttggaaaaagag
aaaatcatgaaagagctggagatcaaagagatgatggctagacacaaacaggaactcact
gaaaaagatgctacaattgcatctcttgaagaaactaataggacactaactagtgatgtt
gccaatcttgcaaatgagaaagaagaattaaataacaaattgaaagatgcccaagagcaa
ctatcaaggttgaaagatgaagagataagtgcagcagctattaaagcacaatttgagaag
cagctgttaacagagagaacactcaaaactcaagctgtgaataagttggctgagatcatg
aatcgaaaagaacctgtcaagcgtggtagtgacacagatgtgcggagaaaagagaaggag
aatagaaaacttcatatggaacttaaatctgaacgtgaaaaattgacccagcagatgatc
aagtatcagaaagaactgaatgagatgcaggctcaaatagctgaagagagccagattcga
attgaactacagatgacactggacagtaaagacagtgacattgagcagctgcggtcacag
ctccaggccttgcatattggtctggatagttccagtataggcagtggaccaggggatgct
gaggcagatgatgggtttccagttcatatcactcaatcacacactatggaatccatgtca
ttcacctaccagcgttcctctacttctctcaatattgccactaagccttccagttctcat
atgctccttgactctgattctgactcagaagaagaatctttgccctacttacctatttca
tcggaacctaatggtacagaatcaagactagaaggatggctttcgttgccagtgcgaaac
aacactaagaaatttggatgggttaaaaagtatgtgattgtaagcagtaagaagattctt
ttctatgacagtgaacaagataaagaacaatctaatccttacatggttttagatatagac
aagttatttcatgtccgaccagttacgcagacagatgtatatagagcagatgctaaagaa
attccaaggatattccagattctgtacgctaatgaaggagaaagtaagaaggaacaagaa
tttccagtggagccagtgggagaaaaatcaaattatatttgccacaagggacatgaattt
attcctacgctctatcatttcccaaccaactgtgaagcttgtatgaagccattgtggcat
atgtttaaacctcctcctgctttagagtgccgtcgctgccatattaaatgtcataaagat
cacatggacaaaaaggaggagattatagcaccttgcaaagtttattatgacatttcaacg
gcaaagaatctattgttattagcaaattctacagaagagcagcaaaagtgggttagtcgg
ttggtgaaaaagatacctaaaaagcctccagctccggacccttttgcacggtcatctcct
agaacttcaatgaagattcaacaaaaccagtctattaggcggccaagtcgacagcttgcc
ccgaacaaaccaagattgcttgatttggcatttaaagactgggattggtcatttgatgat
attgatggtgatgatgatggagatgtttttgatttctga
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integrated database retrieval system
