Equus caballus (horse): 100146648 Help Entry 100146648         CDS       T01058                                  Symbol TH Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism ecb  Equus caballus (horse) Pathway ecb00350   Tyrosine metabolism ecb00790   Folate biosynthesis ecb01100   Metabolic pathways ecb04728   Dopaminergic synapse ecb04917   Prolactin signaling pathway ecb05012   Parkinson disease ecb05030   Cocaine addiction ecb05031   Amphetamine addiction ecb05034   Alcoholism Module ecb_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:ecb00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     100146648 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     100146648 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     100146648 (TH)   09156 Nervous system    04728 Dopaminergic synapse     100146648 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     100146648 (TH)   09165 Substance dependence    05030 Cocaine addiction     100146648 (TH)    05031 Amphetamine addiction     100146648 (TH)    05034 Alcoholism     100146648 (TH) Enzymes [BR:ecb01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      100146648 (TH) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  100146648 NCBI-ProteinID:  XP_023510475 LinkDB All DBs Position 12:complement(34469802..34477573) Genome browser AA seq 496 aa AA seqDB search MPTPSAAAPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAAAAAAA AEPGEPLEAAAVVERDGKAVLNLLFTLRTAKPSSLSRAVKAFETFEAQIHHLETRPAQRP QAGGPHLEYFVRCEVPSPDLPALLSSVRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVT KFDPDLDLDHPGFSDQAYRQRRKLIADIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKG LYATHACREHLEAFELLERFSGYREDNIPQLEDVSRFLKERSGFQLRPVAGLLSARDFLA SLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDE EIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQP YQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFAVKFDPYTLAIDVLDSPHAIRRSLEG VQDELHALANALSTIG NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atgcccactcccagcgccgccgcgccgcaggccaagggcttccggagggccgtctctgag ctggacgccaagcaggccgaggccatcatgtccccgcggttcatcgggcggcggcagagc ctcatcgaggacgcgcgcaaggagcgcgagaaggcggaggcggccgcggccgcggcggca gcggagccgggggagcccctggaggcggcggcggtggtcgagagggacgggaaggctgtg ctgaacctactcttcaccctgaggaccgccaagccctcctcgctgtcccgcgcggtgaag gcctttgagacattcgaagcccaaattcaccacctggagacccggcccgcccagaggccg caggcagggggaccccacctggagtactttgtgcgctgtgaggtgcccagccccgacctg cccgccctgctcagctccgtgcgccgggtggcagaggacgtgcgtggcgctggagagaac aaggtcctctggttcccaaggaaagtttccgagctggacaagtgtcaccacctggtcacc aagtttgatcctgacctggacttggatcatccgggcttctcagaccaggcgtaccgccag cgcaggaagctgattgccgacatagccttccagtacaagcatggtgaccctattccccgc gtggagtacacggccgaggagattgccacctggaaggaggtctacaccaccctcaagggc ctctacgccacgcacgcctgccgcgagcacctggaggccttcgagctgctggaacgcttc agcggctaccgggaggacaacatcccccagctggaggacgtctcccgattcctgaaggag cgctctggcttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggcc agcctggccttccgtgtgttccagtgcacccagtacatccgccatgcctcgtcgcccatg cactccccagagccggactgctgccacgagctgctgggacatgtgcccatgctggccgac cggacctttgcccaattctcccaggacatcggcctcgcatccctgggggcatcggacgag gagattgagaagctgtccacgctgtactggttcacggtggagtttgggctgtgcaaacag aacggcgaggtgaaggcctacggtgcggggctgctgtcctcctatggggagctcctgcac tccctgtcggaggagcctgagatccgggcctttgaccccgacgctgcggccgtgcagccc taccaggaccagacctaccagtccgtctacttcgtgtcggagagtttcagcgacgccaaa gacaagctcaggagctacgcctcccgcatccaacgccccttcgccgtgaagtttgacccg tacacgctggccatcgacgtgctggacagtccccacgccatccggcgctccctggagggt gtccaggacgagctgcacgcccttgccaatgcgctgagcaccatcggctag

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