Enterococcus faecium Aus0085: EFAU085_00175
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Entry
EFAU085_00175 CDS
T02788
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
efau
Enterococcus faecium Aus0085
Pathway
efau00300
Lysine biosynthesis
efau00550
Peptidoglycan biosynthesis
efau01100
Metabolic pathways
efau01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
efau00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EFAU085_00175
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EFAU085_00175
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EFAU085_00175
Enzymes [BR:
efau01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EFAU085_00175
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3323
Motif
Other DBs
NCBI-ProteinID:
AGS74132
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Position
170227..171639
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AA seq
470 aa
AA seq
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MRTRRLGQTLFSQPFLGEISMNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVP
LAGTRDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGA
EVVAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVPAD
EPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNVTNAL
IAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMGLVLDTF
KNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHALKEELNQKY
PQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgcgaacccgccgtttaggccaaacgcttttttcacaaccttttttaggagagatctca
atgaatctaacaatacaagaaattgcacaagccgtgggcagcgaatgctctgcactgaca
aagattaccaatgtcgaatttgacagccggaagataaccgaaggaagtttattcgttcct
cttgctggtacgcgagatggacatgaatttatccagcaagcgatcacaaacggagcatct
gcttcattttggagcttgcctgttgaacaagctccaaaaaattttccagttattcctgta
gcagatcctttgaaagccatgcagcaattggcaacctattacttggaaaaagtaggcgca
gaagtcgttgcaattacaggaagcaatggtaaaaccaccacgaaagatctaaccgcgtct
gtcttgtctgaaaaatacaaaacatataagacgcaaggaaattacaacaataatattggt
cttccttacacgattttgcacatgccccaagatacagaaaagatcgttttggaaatgggc
atggatcacgccaatgaaatcacggaactttcacttatggctcaaccaaaagctgcagca
atcacaatgatcggtgaagcacacatagaaaatcttgggtcgcgagaaggaatcgctaaa
gccaaaatggaaatcactgacggacttgtatcagacggattactcgttgtgcccgcagat
gaaccgttgctgacacctttaacggcaacattagtacaaacagtcacaacattcggtatt
ggaaatggcgatgttcatgcggaagtgacagcaaaaggaaaagcacaaaccgattttgta
gtagaaggagaaacatttacgatcccgctgcctggaagttataatgtaacgaatgctttg
attgcgtatacgatcgggcgcttctttggactgtccatacctgagatacgccaagggctc
gcccatgtttctatcactcaaaacagaaccgaatggctaacggcaggaaatggtgcagct
attttgagcgatgtctacaatgcaaatccaacagccatgggactggtattagatactttt
aaaaatctgccaacaaaaggacgcagaatcgctgtgttagcagatatgctggaattaggg
aaagagtctttaaatatgcatgcgcaaatgagtgaacatatcgatcctgagaaattcgcc
atgattttcctttatggggaacaaatgcatgcactaaaagaagaattgaaccaaaaatac
ccccaactacctgtgttctattttgaaaaagaaaagaataaattgattgatgctatcaaa
caaaatcttgaagcaacagatagtattatgctaaaaggcagcaacagcatgggcttattt
gaagtggtagaacaacttcagcaaatgaaataa
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