Citrifermentans bremense: GEOBRER4_04850
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Entry
GEOBRER4_04850 CDS
T07006
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gbn
Citrifermentans bremense
Pathway
gbn00300
Lysine biosynthesis
gbn00550
Peptidoglycan biosynthesis
gbn01100
Metabolic pathways
gbn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gbn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GEOBRER4_04850 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GEOBRER4_04850 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GEOBRER4_04850 (murF)
Enzymes [BR:
gbn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GEOBRER4_04850 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3046
Motif
Other DBs
NCBI-ProteinID:
BCG45735
UniProt:
A0A6S6M2Y2
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All DBs
Position
585556..586965
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AA seq
469 aa
AA seq
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MAMFTLKEIAEATGGRMIGETGGEASAVSTDSRQVAPGELFVALRGERFDGHDFILKAVS
KGITIFLAEESWAEKNELPTGAGAVLVPDTLRALGDLAAYHRRRFDLKTVCVTGSNGKTT
TKEMLATILAQTGPGLKTEGNLNNLIGLPLTIFRLTGRERWAVLEIGMSEFGEIDRLAEI
AEPQVGIITNAFPAHLETLGSVEGVARAKGELFLRLKSGSVAVYNVDDPLVSACPTHLNV
TRLTFGLRGAEVSSASIQSLGKRGESFTLRLPDGEQQVTLSAYGRHNIYNALAAAAAAHA
LGVPGELIRQGLEEFSPYDKRFQLEEVAGVTLIDDSYNANPASMAAALTTLKEIGGEGRL
VAVLGDMLELGLGTEEAHRELGKLAAAHVDRLYLLGSLVQETAKGALEAGLSPADVVLGE
DHDQLAGELLSFIKPEDCILFKGSRGMKMDKVAKAVRQELAAAGKGGLD
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggcgatgttcacgcttaaggaaatagccgaggcgaccggcggcaggatgatcggggag
acagggggcgaggcctctgctgtcagcaccgattcgcgccaggtggccccgggagagctg
ttcgtggcacttaggggcgagcggttcgacggtcacgacttcatactgaaggcggtctct
aaagggatcaccatcttcctcgccgaggagagctgggcggaaaaaaacgagctcccgaca
ggggccggcgccgttctggtgcctgacacgctgcgcgccctgggggacctggccgcctac
caccgccgccgcttcgacctgaagaccgtctgcgtcaccggcagcaacggcaagaccacg
acgaaagaaatgctggcgacgatcctggcccagacgggaccggggttgaagaccgagggg
aacctcaacaacctgatcgggctgccgctcaccatcttcaggctcaccggccgcgagcgc
tgggccgtcttagagatcggtatgagcgagttcggcgagatcgaccggctggctgagatt
gcggagccgcaggtggggatcatcaccaacgcctttccggcgcacctggagaccctgggg
agcgtggagggtgtggcgcgggccaagggggaacttttcctgcgcctaaagtcgggctcg
gtcgcggtctacaacgtggacgaccccctggtctccgcctgcccgacccatctgaacgtg
acccgtctcaccttcggcctgcggggggccgaggtctcctccgcctccatccagagcctc
ggcaagaggggggagagcttcaccctgaggcttcctgacggagagcagcaggtgacgctg
tcggcctacggaaggcacaacatctacaatgccctggccgcagcagccgcggcgcacgcg
ctcggcgtcccgggcgagctgatccgccaggggctggaggagttctctccctacgacaag
cgcttccagctggaggaggtcgctggggtgaccctgatcgacgacagctacaacgcgaac
ccggcctccatggcggctgcgctcaccaccctgaaggaaatcggtggggaggggcgcctg
gtcgcggttctgggcgacatgctggagcttggactcggcaccgaggaggcgcaccgcgaa
ctgggaaaactggcggcagcccacgtcgaccggctctaccttttgggcagcctggtacag
gagaccgccaagggcgcgctcgaagcggggctttcccccgcggacgtcgtgctgggggaa
gaccacgaccagctggccggggagcttctctccttcataaagccggaagactgcattctc
ttcaagggatcacgaggcatgaaaatggacaaggtggctaaagcggtgcggcaggaactg
gcagccgcaggaaaaggggggcttgactga
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