Geobacillus sp. 12AMOR1: GARCT_00255
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Entry
GARCT_00255 CDS
T03966
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
gea
Geobacillus sp. 12AMOR1
Pathway
gea00300
Lysine biosynthesis
gea00550
Peptidoglycan biosynthesis
gea01100
Metabolic pathways
gea01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
gea00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GARCT_00255 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GARCT_00255 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GARCT_00255 (murF)
Enzymes [BR:
gea01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GARCT_00255 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AKM17603
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Position
244172..245548
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AA seq
458 aa
AA seq
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MMKRTVRQIAEMSGGRCVKPEWETIAVSGVSTDTRAIQAGNLYVPLRGATFNGHDFVQEA
VQKGAAAVLWAEREGTPPEGVPVVVVDDTLLALQRLAARYREQLGMKVIGVTGSNGKTTT
KDMIAALLAANYRVQKTEGNLNNHIGVPLTLLSLEEDTEIAVVEMGMSGFGEIERLTLIA
KPDAAVITNIGESHLQELGSREGIAKAKLEILEGVHRDGLFVYHGDEPLLAERVPHLSLP
RHVVTFGAGAENDYYPTDVRIEAGGTSFAINVLPGRTLFMPVLGKHHVYNALAAIAVARF
FGVGWDSIDAALSRLRLTRMRTEVVKTKHGFTVINDAYNASPTSTRAALTLLGELDGYRN
KIAVLGDILELGEKEAEFHEEIGAMLRPEMADYVFTYGPLARYIAEAAAPFFADGRVRAF
DDKAALAEAVRSVASPDDIVLLKASRGMRLEELLRYWV
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgatgaaacggacggtgcggcaaattgcggagatgtcaggcggtcggtgcgtgaagccg
gaatgggagacgattgccgtcagcggcgtatcgacagacacgagagcgatccaagccggc
aacttgtacgttccgttgcgcggtgcgacctttaacggccacgatttcgtgcaagaagcg
gtgcaaaaaggagccgccgccgtactgtgggcggaaagggaaggaacgccgccggaaggt
gtgccagtggtcgttgtggatgatacgcttttggcattgcagcggctcgccgcccgctac
cgcgagcagcttggaatgaaggtgatcggcgtcactggcagcaacggcaaaacgacgacg
aaagatatgattgccgcgttgttggcggccaactaccgcgtgcaaaaaacggaagggaac
ctcaacaaccatattggcgtaccgctgacgctgctttcgctcgaggaagacacagagatt
gccgttgtcgaaatggggatgagcggattcggcgaaatcgagcggctcacgttgattgcc
aaaccggatgcggccgtcattaccaacatcggggaatcacatttgcaagagcttggttca
cgggaaggcatcgccaaagccaaattggaaattttggaaggggtgcaccgcgatggcttg
ttcgtctaccatggcgacgaaccgctgttggccgagcgggtcccgcatttatctcttccc
cgccacgtcgtgacatttggagcgggagcggaaaacgactactacccgaccgatgtgcgc
attgaagcgggggggacgtcatttgccattaacgtgcttccgggtcggacgctctttatg
ccggtgttgggaaaacatcacgtatacaacgcgctcgcagccatcgcggtagcccgcttt
tttggcgtcggctgggacagcatcgatgcggccttgtcccgtctgcgattgacgcgcatg
cgcaccgaagttgtcaaaacaaagcatggcttcacggtcattaacgatgcttacaacgcc
agcccgacttcgacgcgtgcagcgttgacgctgcttggggaactggacgggtatcggaac
aaaattgccgtcttgggcgatatattggagcttggcgaaaaagaagccgagtttcacgaa
gagatcggggcgatgctgcggccggagatggcggattacgtgttcacttatggaccgctg
gcgcgctatattgcggaagctgctgcaccgttttttgccgacggtcgggtgcgggcgttt
gacgataaggcggcattggccgaggcggtgcgttcggtcgcttctccggacgatattgtc
ttgttgaaggcatcgcgcggcatgagattggaagaactgctccgctattgggtgtaa
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