Hyphomicrobium denitrificans 1NES1: HYPDE_23728
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Entry
HYPDE_23728 CDS
T02646
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hdt
Hyphomicrobium denitrificans 1NES1
Pathway
hdt00300
Lysine biosynthesis
hdt00550
Peptidoglycan biosynthesis
hdt01100
Metabolic pathways
hdt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hdt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HYPDE_23728
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HYPDE_23728
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HYPDE_23728
Enzymes [BR:
hdt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HYPDE_23728
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGK56431
UniProt:
N0B7B7
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All DBs
Position
230122..231540
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AA seq
472 aa
AA seq
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MQPLWTFSELSAALGVKPEGGVDRPVAGVSIDTRTLQPGDLFVALKDQRDGHDFVSSAFE
AGAAAALVVESYRRQPKDGALLRVPDTLRGLEALGRAARARINPDARVVAVTGSAGKTGT
KEMLRACLAHLGTTHASEKSYNNHWGVPLTLARMSRETRFSVFEIGMNHAGEIRPLTKMV
RPHAAIVTTVEAVHLEYFPSVQAIADAKGEIFEGLVPGGTAVIKYDNPHAGRLTSIAKRF
GAKPVTFGFSAGADVRGDDLKLGYDGSALTVRFGERRIPLQLAMPGRHIAENALAVVAAI
DAIGADVEKTLSVLANLQPPSGRGARSVLHIEGGEALLIDESYNANPASMRAALAALASV
PRQKFSRRIAVLGDMLELGSDAPALHQGLKEAVEDAGIDLIFACGPHMKGLYDALPKSKK
GGYAAASSSLPDALLSNLRRGDVIMVKASNGTRLGPVVAALKAQFGNDGSVS
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgcaaccgttgtggacgttttccgaattgagcgctgcgctcggagtcaagcctgagggt
ggggtcgaccggccggtcgccggagtatcgattgatacacgtacactgcagcccggcgat
ctttttgtggcgttgaaagatcagcgcgatggccacgatttcgtatcgtccgcattcgag
gcgggcgcggctgcggcgctcgttgtggagagttacaggcgccagccgaaggacggcgca
ttgttgcgcgtaccggacacattgagggggcttgaagcgcttggccgcgcggcgcgagcg
cggatcaacccggacgcccgcgttgttgcggtgacgggcagtgccggcaagacggggacc
aaggaaatgctgcgcgcgtgtcttgcgcatcttggcaccacccacgcctccgaaaagtcc
tacaacaatcactggggcgttccgctgacgctcgcacgcatgtcacgcgagacgcggttc
agcgtcttcgagatcggcatgaatcatgccggggaaatccggccgctcacgaagatggtc
cgcccgcatgccgccatcgttacgacggtcgaagccgtgcatctcgaatactttccgtcg
gtccaagcgatcgcggatgcgaagggcgagattttcgaggggctcgtgccgggcggaacg
gccgtcatcaaatacgacaatccgcacgcgggccggctcacgtcgattgccaagcgtttc
ggcgcgaagccggtaaccttcggtttcagtgcgggcgccgacgttcgtggcgacgatctg
aagcttggctacgacggcagtgcgctgaccgtccggttcggcgaacggcgaattcctctc
cagcttgcgatgcccggacgccatatcgccgaaaacgcgttggcggtcgtcgctgcaatt
gatgcgatcggtgccgacgtcgaaaagaccctatcggtgcttgccaacctgcagccgccg
agcggccgtggcgcgcggagcgttcttcatatcgagggaggcgaagcgcttctgatcgat
gagagctacaacgcaaacccggcctcgatgcgggccgcgctggcggcgctcgcatccgtg
ccgcggcagaaattctcacgcaggatcgcggtcttgggcgatatgctggaactcggctcc
gatgcgccggcgcttcatcaaggtctcaaggaggctgtggaggacgccgggatagacctt
atatttgcctgcgggccgcacatgaagggcctttatgatgccctaccgaagtccaaaaag
ggcggctacgctgcagcatcgtcttcgcttcctgatgcgctgctatccaatctgcgacgt
ggcgacgtcatcatggtcaaggcttcgaatggaacgcgtctcggtccggtcgttgcagca
ttgaaagcgcagttcgggaacgacggctccgtctcgtag
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