Ketogulonicigenium vulgare Y25: EIO_0399
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Entry
EIO_0399 CDS
T01338
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kvu
Ketogulonicigenium vulgare Y25
Pathway
kvu00300
Lysine biosynthesis
kvu00550
Peptidoglycan biosynthesis
kvu01100
Metabolic pathways
kvu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kvu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EIO_0399
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EIO_0399
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EIO_0399
Enzymes [BR:
kvu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EIO_0399
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
TPP_enzyme_M
Motif
Other DBs
NCBI-ProteinID:
ADO41570
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Position
371111..372547
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AA seq
478 aa
AA seq
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MSALWTGVEAAAATGGRLTRDFAVTGVSIDTRTLQPGDLFVALAAARDGHDFVASALEKG
AAAALVSRVPEGLPANAPLLIVDDVLAALEAMGRAARARTKAKIVAVTGSVGKTSTKEML
RTVLAAAGRTHASEASYNNHWGVPLTLARMPADTEYGVLELGMSHPGEIAPLSRMVQPHV
GVITTVAAAHFEAFGSIEGIAHEKAAIFEGLLPRGTAVVNGDLAVSPILIAAAKDKGARV
ITFGETPRNHHRLTDLRVRAGVTVASGRAWRTPFHMKVASAGRHFAVNALAVIAAADALG
MDRARALVALAEWAPPAGRGMRQIISLDPLREGRTFELIDDAYNANPTSMAAALDVLALS
EPVDGVGRLARGRRVAVLGDMLELGPDEMALHAALAEDHALTAADLIVCVGTRMKALHAA
LPAERAYWLATPEEILPHITRIADAGDVVLVKGSKGSRVSIIVDALRKLGCAPPETLE
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcgctttggaccggggtcgaggccgctgccgcgacgggggggcgcctgacgcgt
gattttgccgtaacgggtgtctctatcgatacccgcactttgcagccgggcgatctgttc
gtggcgctggccgctgcgcgcgatggccatgactttgttgcgagcgcgctggaaaagggt
gcggctgctgcgctggtgtcgcgcgtgcccgagggtctgcccgcgaacgcgccgctgctg
attgttgatgacgtgctggctgcgctcgaggccatgggccgtgcggcgcgcgcgcggacc
aaggcgaagatcgtcgcggtcacgggatcggtcggcaaaacctcgaccaaggaaatgctg
cgcaccgtgctggcggctgcggggcgcacccatgcgtctgaggccagctataacaaccat
tggggcgtgccgctgacgctggcgcggatgcccgccgacaccgaatatggtgtgctcgaa
ctgggcatgagccatccgggcgagatcgcgccgctgtcgcgcatggtgcagccgcatgtt
ggcgtcatcaccaccgtcgccgccgcgcatttcgaggcctttggcagtatcgagggcatc
gcccatgagaaagcggcgatattcgagggacttttgccgcgcggcaccgctgtcgtgaac
ggcgatctagcggtttccccgatcctgatcgctgcggcaaaggacaaaggcgcgcgggtc
atcacctttggcgagacgccccgcaatcaccaccgcctgaccgatctgcgcgtgcgcgcc
ggtgtcacggttgcatcaggccgtgcatggcgcacgccctttcacatgaaggtcgcaagc
gccggtcgccatttcgcggtgaacgcactggcggtgatcgcggcggcggatgctttgggc
atggaccgtgcgcgggcactggtcgcgctggccgaatgggcaccgcctgcaggtcgcggt
atgcgccagatcatcagccttgatccgctgcgcgaggggcgcaccttcgagctgatcgac
gacgcgtataacgcgaacccgacctcgatggcggcggcgctggatgtgctggccttgtcc
gagccggtcgacggcgtcgggcggctggcgcgcgggcgacgcgttgccgtgttgggcgat
atgctggagctcggccccgacgagatggccctgcacgccgcccttgccgaggatcacgcc
ctgacggccgccgatctgatcgtttgtgtcggcaccaggatgaaggcgctacacgccgct
ttgcccgccgagcgggcctattggctggccacccccgaagagattttgccccatatcacc
cgcattgcagatgcgggcgatgtggtgctggtaaaaggttcaaaaggcagccgtgtctcg
atcatcgtggatgcgctgcgcaagcttggctgcgcgccgcctgagactttggaatag
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