Limosilactobacillus reuteri I5007: LRI_1714
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Entry
LRI_1714 CDS
T02701
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lrt
Limosilactobacillus reuteri I5007
Pathway
lrt00300
Lysine biosynthesis
lrt00550
Peptidoglycan biosynthesis
lrt01100
Metabolic pathways
lrt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lrt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LRI_1714
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LRI_1714
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LRI_1714
Enzymes [BR:
lrt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LRI_1714
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MurT_C
DUF3323
Motif
Other DBs
NCBI-ProteinID:
AGN99923
UniProt:
R9WJL4
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Position
complement(1762673..1764052)
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AA seq
459 aa
AA seq
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MKMKLAEIAKAINAQNDIEQWKDVEVTSVSFDSRHLDQGSLFVPLQGAQDGHQYVPSAFT
NGAVASLWASDHEITDQTHPLLVVNDPLAALQQLGKYYLHKINPIVVAVTGSNGKTTTKD
MIASILSTQFNVTKTYANFNNEIGVPVTLLNMESNTEAVVVEMGMDRFDQLDFLSKLVNP
DIAVITMIGEAHIEFFGTRDKIADAKMEITHGLKEDGMLVFNGDEPLLEERVKDLTQRQM
RFGRQLSNNLYATSVHDEPRQLSFTVNEWPDEEFTIPMVGEYNINNALAAMEVGKILHIT
PAHMKQALANVELTENRAEWVKGKNGEQILSDVYNSNPTAAKEVLKTIAETPVDGRRIAV
LGDMLELGDAAPKLHASLAEEIDHQKIASVYLVGEQMKNLKDKLIQEGYPAEDIHHYAAS
DLQQLIADLTATLTGEDIVLLKASHGIHLEEVLTALKAE
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgaaattagcggaaattgccaaggcgatcaacgcacaaaatgacattgaacaa
tggaaagacgtagaagtgactagtgtgtcatttgacagtcgacacttagatcaagggagc
ttatttgttccgttgcaaggtgcccaagacggccaccaatacgtaccgagtgcttttacc
aatggtgcagtagctagtttatgggctagtgaccatgagataacggatcagacgcacccg
ttattagtcgttaatgatccactagcggcccttcaacaactagggaagtactacttgcat
aagatcaatccgattgttgttgcagttacgggcagtaatggtaagacgacgactaaagat
atgattgcgtcaatcttaagtacgcagtttaatgtcacaaagacatatgctaattttaat
aatgagattggggttccagtaacgcttcttaacatggagtctaataccgaagcagtggta
gttgagatgggcatggaccgttttgaccagcttgacttcttaagtaagcttgtaaatcct
gacattgccgttattacaatgatcggggaagcacatatcgaattcttcgggactcgtgat
aagattgctgatgcaaagatggaaattacccatggcctaaaggaagatggaatgctagta
tttaatggggatgaaccattattagaggaacgggtaaaagatcttacccaacgacagatg
cgctttggtcggcaactaagcaataatttgtatgcaacaagtgtccacgatgaaccacga
cagctatcatttactgtcaacgaatggccagatgaagaattcactattccaatggttggt
gaatacaatattaataatgcgttagcggctatggaagtgggtaagattctgcatattact
cccgctcacatgaagcaagcattggcaaacgttgaattaacggaaaatcgtgctgaatgg
gttaaaggaaagaatggtgaacagatcttaagtgatgtttacaattcaaacccaaccgct
gccaaagaagtccttaaaacaatcgcggaaacgccagtagatggtcgccgaattgccgta
ttaggggacatgctagaattaggggatgctgcgccaaagttgcatgctagcttagcagaa
gagattgaccaccaaaagattgctagtgtttaccttgtaggcgaacaaatgaaaaatctt
aaagataagttgatccaagaaggttacccagctgaagatatccatcattatgctgccagt
gaccttcaacaattaattgccgatcttacggctactttgacaggtgaggatattgttcta
ttgaaagcaagccatggtattcacctagaagaagtcttgacggcattaaaagcagaatag
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