KEGG   Lipotes vexillifer (Yangtze River dolphin): 103091203
Entry
103091203         CDS       T03090                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve04010  MAPK signaling pathway
lve04012  ErbB signaling pathway
lve04620  Toll-like receptor signaling pathway
lve04664  Fc epsilon RI signaling pathway
lve04668  TNF signaling pathway
lve04912  GnRH signaling pathway
lve04926  Relaxin signaling pathway
lve04935  Growth hormone synthesis, secretion and action
lve04936  Alcoholic liver disease
lve05132  Salmonella infection
lve05135  Yersinia infection
lve05142  Chagas disease
lve05161  Hepatitis B
lve05166  Human T-cell leukemia virus 1 infection
lve05167  Kaposi sarcoma-associated herpesvirus infection
lve05169  Epstein-Barr virus infection
lve05208  Chemical carcinogenesis - reactive oxygen species
lve05417  Lipid and atherosclerosis
lve05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lve00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103091203 (MAP2K4)
   04012 ErbB signaling pathway
    103091203 (MAP2K4)
   04668 TNF signaling pathway
    103091203 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103091203 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    103091203 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    103091203 (MAP2K4)
   04926 Relaxin signaling pathway
    103091203 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    103091203 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    103091203 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103091203 (MAP2K4)
   05161 Hepatitis B
    103091203 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103091203 (MAP2K4)
   05169 Epstein-Barr virus infection
    103091203 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103091203 (MAP2K4)
   05135 Yersinia infection
    103091203 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    103091203 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103091203 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    103091203 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103091203 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lve01001]
    103091203 (MAP2K4)
Enzymes [BR:lve01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     103091203 (MAP2K4)
Protein kinases [BR:lve01001]
 Serine/threonine kinases: STE group
  STE7 family
   103091203 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 103091203
NCBI-ProteinID: XP_007455070
UniProt: A0A340X7M8
LinkDB
Position
Unknown
AA seq 410 aa
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
NPPFKSTARFTLNPNPAGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggccccgtggggtccccggcgcccggccacccggccgtcagcagcatgcagggcttt
cagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgca
aatccacctttcaaatctacagcaaggtttactctgaatcccaatcctgcaggagttcaa
aacccacacatagagagactgagaacacacagcattgaatcgtcaggaaaactgaagatc
tcccctgagcagcactgggatttcactgcagaggacttgaaagaccttggagaaattgga
cgaggcgcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatggcg
gttaaaagaattcgctcaacagtggatgaaaaagagcaaaaacaacttctcatggatttg
gatgtagtgatgcgaagtagtgattgcccgtacattgttcagttttatggtgcactcttc
agagagggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttac
aaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcact
ttagcaactgtgaaagcactcaaccacttaaaagaaaacttgaaaatcattcacagagat
atcaaaccttccaatattcttctggatagaagtggaaatattaaactctgcgactttggc
atcagtggacagcttgtggactccattgccaagacaagagatgctggttgcaggccatac
atggcacctgaaagaatagacccaagtgcgtcacgacaaggatatgacgtccgctctgat
gtctggagtttggggatcacattgtacgaattggccacaggccgatttccttatccaaag
tggaatagtgtgtttgatcaactaacacaagttgtgaaaggagacccaccacagttgagt
aattctgaggaaagggaattttccccaagtttcatcaactttgtcaacttgtgccttacc
aaggatgaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttgatg
tatgaagagcgcgctgtcgaggtcgcatgctatgtttgtaaaatcctggatcaaatgcca
gctactcccagctctcccatgtatgtcgactga

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