Mycolicibacterium brumae: L2Z93_001450
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Entry
L2Z93_001450 CDS
T08531
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mbrm
Mycolicibacterium brumae
Pathway
mbrm00300
Lysine biosynthesis
mbrm00550
Peptidoglycan biosynthesis
mbrm01100
Metabolic pathways
mbrm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mbrm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
L2Z93_001450
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
L2Z93_001450
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
L2Z93_001450
Enzymes [BR:
mbrm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
L2Z93_001450
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UWW08396
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Position
1494175..1495713
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AA seq
512 aa
AA seq
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MIELSLAEIADIVGGRLADISADDAATTRVTGTVEFDSRAITPGGLFLAMPGARHDGHDH
AAAAIAAGAVAVLAARPVGVPAVIAAPADSADRGAGVLEHDRDGAGAAVLAALAKLAAEV
ARRLTAAGLRIVGVTGSAGKTSTKDLLAAVLAPLGQVVAPPGSFNNELGHPWTVLRATED
TDFLILELSARHPGNIAALAAIAPPSIGVVLNVGTAHLGEFGSRQAIADTKSELAQAIPA
SGAVILNADDPAVAAMAAVTDARVVRVSRAPGTEAQLWAEDVRLDELARPRFRLCRAGES
VEVALAVHGDHQVSNALCAAAVACECGANLAQAAAALAGAGPVSARRMDVRTRADGVTVI
NDAYNANPDSMAAGLKALAWMARGDGGPPRRSVAVLGEMAELGDDAITEHDRIGRLVVRL
DVSLLVAVGAGRPMSALLNGAVMEGSWGAEAVAVADADAALELLRAELAPGDVVLVKASN
SVGLGALGETLAGDATDPDAPKPAAVGEDSTR
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagctgagcctggccgagatcgcggacatcgtcggtggccgcctcgcggacatc
agcgccgacgacgccgccaccacccgagtcaccggaaccgtcgaattcgattcccgcgcg
atcacccccggcggattgttcctggccatgcccggcgcgcgccacgatggccacgaccac
gccgcagccgcgatcgcggcgggcgcggtcgcggtgctggccgcgcgcccggtcggcgtt
cccgccgtcatcgccgcgccggcggactccgccgaccggggcgccggggtgctcgaacac
gatcgcgacggcgccggcgcagcggtgctcgccgcgctggccaaactcgccgccgaggtc
gcccgccggctgaccgcggccggcctgaggatcgtcggggtgaccggctcggccggcaaa
acctccaccaaggacctgctggccgcggtgctcgccccgctcgggcaggtcgtcgccccg
cccgggtcgttcaacaacgaactgggccacccctggacggtgctgcgggccaccgaggac
accgacttcctgatcctggagctttccgcccgccaccccggcaatatcgcggcgctggcc
gccatcgcgccgccgtcgattggagtggtgctcaatgtcggcaccgcgcacctcggcgaa
ttcggctcccgccaggccatcgccgacaccaaatccgaactggcccaggcgatcccggcc
tccggcgcggtcatcctcaacgccgacgacccggccgtggcggcgatggccgcggtcacc
gacgcccgggtggtccgggtctcccgcgcgccggggaccgaggcgcagctgtgggccgag
gacgtccggctcgacgagctggcccggccccggttccggctgtgccgcgccggggagtcg
gtcgaggtggcactggccgtgcacggcgaccaccaggtgtccaacgcgctgtgcgcggcc
gccgtggcctgcgagtgcggcgcgaacctggcccaggcggccgccgcgctggccggcgcc
ggccccgtctcggcgcgccggatggatgtgcgcacccgagccgacggggtgaccgtcatc
aacgacgcctacaacgcgaatcccgattcgatggccgccgggctgaaggcgctggcctgg
atggcccgcggcgacggcggcccgccgcggcgcagcgtcgcggtgctcggcgaaatggcc
gaactcggcgacgacgccatcaccgaacacgaccggatcggccggcttgtggtgcgcctg
gacgtctccctgctggtggccgtcggcgccgggcgaccgatgagcgcgctgctcaacggc
gcggtgatggagggctcctggggcgccgaagccgtcgccgtcgccgacgccgacgccgcg
ctggaattgctgcgcgccgagctcgccccgggcgacgtggtgctggtgaaggcgtcgaac
tcggtcggtctgggcgcgctgggggagaccctggccggtgacgcgaccgacccggatgcg
ccgaaaccggccgcggtgggggaggattccacccgatga
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