KEGG   Mandrillus leucophaeus (drill): 105528792
Entry
105528792         CDS       T08763                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
mleu  Mandrillus leucophaeus (drill)
Pathway
mleu04010  MAPK signaling pathway
mleu04012  ErbB signaling pathway
mleu04620  Toll-like receptor signaling pathway
mleu04664  Fc epsilon RI signaling pathway
mleu04668  TNF signaling pathway
mleu04912  GnRH signaling pathway
mleu04926  Relaxin signaling pathway
mleu04935  Growth hormone synthesis, secretion and action
mleu04936  Alcoholic liver disease
mleu05132  Salmonella infection
mleu05135  Yersinia infection
mleu05142  Chagas disease
mleu05161  Hepatitis B
mleu05166  Human T-cell leukemia virus 1 infection
mleu05167  Kaposi sarcoma-associated herpesvirus infection
mleu05169  Epstein-Barr virus infection
mleu05208  Chemical carcinogenesis - reactive oxygen species
mleu05417  Lipid and atherosclerosis
mleu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mleu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105528792 (MAP2K4)
   04012 ErbB signaling pathway
    105528792 (MAP2K4)
   04668 TNF signaling pathway
    105528792 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    105528792 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    105528792 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105528792 (MAP2K4)
   04926 Relaxin signaling pathway
    105528792 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    105528792 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    105528792 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105528792 (MAP2K4)
   05161 Hepatitis B
    105528792 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105528792 (MAP2K4)
   05169 Epstein-Barr virus infection
    105528792 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105528792 (MAP2K4)
   05135 Yersinia infection
    105528792 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    105528792 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105528792 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    105528792 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105528792 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mleu01001]
    105528792 (MAP2K4)
Enzymes [BR:mleu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     105528792 (MAP2K4)
Protein kinases [BR:mleu01001]
 Serine/threonine kinases: STE group
  STE7 family
   105528792 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal Seadorna_VP7 ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 105528792
NCBI-ProteinID: XP_011821067
LinkDB
Position
Unknown
AA seq 281 aa
MVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICM
ELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLD
RSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLY
ELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKY
KELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 846 nt   +upstreamnt  +downstreamnt
atggtccacaaaccaagtgggcaaataatggcagttaaaagaattcggtcaacggtggat
gaaaaagaacaaaaacaacttcttatggatttggatgtagtaatgcggagtagtgattgc
ccatacatcgttcagttttatggtgcactcttcagagagggtgactgttggatctgtatg
gaactcatgtctacctcgtttgataagttttacaaatatgtatatagtgtattagatgat
gttattccagaagaaattttaggcaaaatcactttagcaactgtgaaagcactaaaccac
ttaaaagaaaacttgaaaattattcacagagatatcaaaccttccaatattcttctggac
agaagtggaaatattaaactctgtgacttcggcatcagtggacagcttgtggactctatt
gccaagacaagagatgctggctgtaggccatacatggcacctgaaagaatagacccaagc
gcatcacgacaaggatatgatgtccgctctgatgtctggagtttggggatcacattgtat
gagttggccacaggccgatttccttatccaaagtggaatagtgtatttgatcaactaaca
caagtcgtgaaaggagatcctccgcagctgagtaattctgaggaaagggaattctcccca
agtttcatcaactttgtcaacttgtgccttacgaaggatgaatccaaaaggccaaagtat
aaagagcttctgaaacatccctttattttgatgtatgaagaacgtgccgttgaggtcgca
tgctatgtttgtaaaatcctggatcaaatgccagctactcccagctctcccatgtatgtt
gattga

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