Mustela nigripes (black-footed ferret): 132006541
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Entry
132006541 CDS
T09425
Symbol
PAICS
Name
(RefSeq) bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase isoform X1
KO
K01587
phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:
4.1.1.21
6.3.2.6
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00230
Purine metabolism
mnp01100
Metabolic pathways
Module
mnp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132006541 (PAICS)
Enzymes [BR:
mnp01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.21 phosphoribosylaminoimidazole carboxylase
132006541 (PAICS)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
132006541 (PAICS)
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Gene cluster
GFIT
Motif
Pfam:
SAICAR_synt
Myb_DNA-bind_4
AIRC
Myb_DNA-bind_3
VCD
Myb_DNA-bind_5
DUF639
Motif
Other DBs
NCBI-GeneID:
132006541
NCBI-ProteinID:
XP_059240383
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Position
1:247485783..247531894
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AA seq
865 aa
AA seq
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MESGAGKHWTEEEVKALLSVWAEKNIRKQLYGTLRNKGIFIYIAKRLQALGVYRDWKQCR
AKYKNLKYEYRTVKYAHNSGDSSKTMKFFHDLDAILQYEPATQLREEDANDRCLATLSQS
AAPGTTEGNMSVTLEDKEDLSGNPLLLVSHIRPMELGNSTSFMEPCINSPFIPTIANEGG
KHWTVPEVRALIGIWSDISIQQQLEGTVRNKRIFEQIAAKLQKFGIERDWKQCRTKYKNL
KHEYKIVRMAQDQGITKSMKFFTELDAILGHNKTEKSQQQEFQDEKQANGCANVKTEENR
TVIAGDAAEDDFVGHMSEDLREGDVKQSPATEEDTISTVSEYVGGPKAPQSITVSELFEG
HTKNPRTLSVKRKAHEDGPVSVSLKKTAPEITANGFPQCVTERKDSTECFYRQETPYAIQ
FHQSLSSLPGAAAAPSPRRIMATAEVLNIGKKLYEGKTKEVYELPDSPGKVLLQSKDQIT
AGNAARKNHLEGKAAISNKTTSCIFQLLKEAGIKTAFTRKCGETAFIAPKCEMIPIEWVC
RRIATGSFLKRNPGVKEGYKFYPPKVELFFKDDANNDPQWSEEQLIAAKFCFAGLVIGQT
EVDIMSHATQAIFEILEKAWLPQNCTLVDMKIEFGVDITTKEIVLADVIDNDSWRLWPSG
DRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLSH
CEKIKKACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMS
GNTAYPVISCPPLTPDWGAQDVWSSLRLPSGLGCSTILSPEGSAQFAAQIFGLNNHLVWA
KLRASILNTWISLKQADKKIREGNL
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atggagagtggagcaggaaagcactggactgaagaagaggttaaagctttgctaagtgtc
tgggcagaaaaaaatatacgaaaacaactttatggaaccctgagaaataaaggaatattt
atttacattgctaaaaggctgcaagcactaggagtatacagagattggaaacagtgccgg
gcaaagtacaaaaatctcaaatatgaatacagaacagttaaatatgcccataactctgga
gacagctctaaaactatgaagttcttccatgatctggatgcgatcctgcagtatgaacct
gccacacaattaagagaggaagatgcaaatgacaggtgcctggcaacgctgagccaaagt
gcagctccagggaccactgaaggcaacatgtcagttacattagaagataaagaagacctc
tcaggaaatcctttacttttggtttctcatatcagaccaatggaactaggtaactctaca
tcatttatggaaccctgtattaattcaccttttattccaactatagcaaatgaaggagga
aaacactggactgtaccagaagtcagggctctaattggcatctggtctgatataagtata
caacaacaactagaaggaacagtgagaaataaaaggatatttgaacaaattgctgcgaag
cttcagaaatttggaatagaaagagactggaaacagtgcagaacaaagtataaaaactta
aaacatgaatataagattgtaagaatggctcaagaccaaggcataactaagagtatgaaa
ttttttacggagttggatgctattttgggacacaataaaacagagaaatcacaacaacag
gaattccaagatgaaaaacaagccaacggatgtgccaatgtaaaaacagaagagaatcgg
acagtcattgctggagatgcggctgaagatgactttgttggtcatatgtcagaagaccta
agagagggagatgtaaaacaaagtcctgctacagaggaagataccataagtacagtctca
gaatacgtgggcggccccaaagcaccacaaagtatcactgtgtcagaattatttgaaggt
cataccaaaaacccaagaactttgagcgtcaaaagaaaagcacacgaagatggaccagtg
tctgtatctcttaagaaaaccgctcctgagatcactgcaaatgggtttcctcaatgtgta
acagaacggaaagattctacagaatgtttctacagacaggaaaccccatacgcgatccaa
tttcatcagagtctttcctctcttcccggcgcggcggctgcccccagcccacgcagaata
atggcgacagctgaggtactgaatattggtaagaaactctatgagggtaaaacaaaagaa
gtttatgaattgccagatagtccaggaaaagtcctcctgcagtccaaggaccagataaca
gcaggaaatgcagccagaaagaatcatctggaaggaaaagctgcaatctcaaataaaact
accagttgtatttttcagttgttaaaggaagcaggtatcaaaactgctttcaccagaaaa
tgtggggagacagctttcattgcacctaagtgtgaaatgattccaattgaatgggtctgt
agaagaatagcaactggttcttttctcaaaagaaatcctggtgtcaaggagggatataag
ttctacccacctaaagtggagctgtttttcaaggatgatgccaacaatgatccacagtgg
tctgaggaacagctaattgctgcaaaattttgctttgctggacttgttataggccagact
gaagtggatatcatgagtcatgctacacaggctatttttgaaatattggagaaagcctgg
ttgccgcagaactgtacattggttgatatgaagattgaatttggtgttgatataaccacc
aaagagattgttcttgctgatgttattgataatgattcctggagactctggccatcagga
gatcgaagccaacagaaagataaacagtcatatcgtgacctaaaggaagtaactcccgaa
gggctccagatggtgaagaaaaactttgagtgggttgcagaaagagtggagttgcttctg
aaatcagaaagccagtgcagagttgtagtattgatgggctcaacttctgatctcagtcac
tgtgaaaaaataaagaaggcttgtggaaattttggcattccatgtgaacttcgggtaacg
tctgcccataaagggccagatgaaactctgaggattaaagcagaatatgaaggggatggc
attcctactgtatttgtggcagtggcaggcagaagcaatggtttaggaccagtgatgtcc
ggtaataccgcatacccagttatcagctgccctccactcactccagactggggagctcag
gatgtgtggtcttctcttcgactacccagtggtcttggctgttcaaccatactttctcca
gaaggatcagctcagtttgctgctcagatatttggattaaacaaccatttggtatgggct
aagctgcgagcaagtatattgaacacatggatttccttgaagcaggctgacaagaaaatc
cgagagggcaatttgtaa
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