Neisseria meningitidis M04-240196 (serogroup B): NMBM04240196_0424
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Entry
NMBM04240196_0424 CDS
T01948
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nmq
Neisseria meningitidis M04-240196 (serogroup B)
Pathway
nmq00300
Lysine biosynthesis
nmq00550
Peptidoglycan biosynthesis
nmq01100
Metabolic pathways
nmq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nmq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NMBM04240196_0424 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NMBM04240196_0424 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NMBM04240196_0424 (murF)
Enzymes [BR:
nmq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NMBM04240196_0424 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADZ00939
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Position
433640..434998
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AA seq
452 aa
AA seq
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MKPLDLNFICQALKLPMPSESKPVSRIVTDSRDIRAGDVFFALAGGRFDAHDFVEDVLAA
GAAAVVVSREDCVAMDGALKVDDTLTALQMLAKAWRENVNPFVFGITGSGGKTTVKEMLA
AVLRRRFGDNAVLATAGNFNNHIGLPLTLLKLNEKHRYAVIEMGMNHFGELAVLTQIAKP
DAALINNALRAHVGCGFDGVGDIAKAKSEIYQGLCSDGMALIPQEDANMAVFKTATLNLN
TRTFGVDSGDVHAENIVLKPLSCEFDLVCGDERAAVVLPVPGRHNVHNAAAAAALALAAG
LSLNDVAEGLQGFSNIKGRLNVKSGIKGATLIDDTYNANPDSMKAAIDVLARMPAPRIFV
MGDMGELGEDEAAAMHAEVGAYARDQGIEAAYFVGDNSVEAAEKFGADGLWFAAKDPLIQ
VLRHDLPERATVLVKGSRFMQMEEVVEALEDK
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaaaccactggacctaaatttcatctgccaagccctcaagcttccgatgccgtctgaa
agcaaacccgtgtcgcgcatcgtaaccgacagccgcgacatccgcgcgggcgatgtgttt
ttcgcattggcgggcgggcggtttgatgcgcatgattttgttgaagacgtattggctgct
ggtgcggcggcggttgtggtttcgcgcgaagattgcgttgcaatggatggcgcgttgaaa
gtcgatgacacgcttaccgcgttgcaaatgttggcgaaggcgtggcgcgagaatgtgaac
ccgtttgtgttcggtattaccggttcgggcggtaagacgacggtgaaggaaatgttggct
gcggtattgcgccgccgtttcggcgataatgccgttttggcgacggcaggcaacttcaac
aaccacatcggattgccgttgactttgttgaaattaaacgaaaaacaccgctatgccgtg
attgaaatgggtatgaaccattttggcgaactggcggttttgacacaaatcgccaaaccc
gatgccgctttgatcaacaacgccctgcgtgcccatgtcggctgcggtttcgacggagtg
ggcgatattgccaaagcgaaaagcgagatttatcaaggcttatgttcagacggcatggca
ctgattcctcaagaagatgccaatatggctgtcttcaaaacggcaacgcttaatttgaat
acgcgcactttcggcgtcgatagcggcgatgtccacgcggaaaatatcgtgctgaaaccg
ttgtcgtgcgaatttgatttggtgtgcggcgatgagcgcgccgccgtggtgctgcctgtt
cccggccgccacaatgtccacaacgccgccgctgccgccgcgctggctttggctgcgggt
ttgagtttgaacgatgtggcggaaggtttgcaaggcttcagcaacatcaaaggccgtctg
aacgtcaaatccggcatcaaaggcgcaaccctgattgacgatacctacaacgcgaacccc
gacagtatgaaagccgcgattgacgtgttggcgcgtatgcctgcgccgcgtattttcgtg
atgggcgatatgggcgaactgggtgaggacgaagccgccgccatgcacgccgaagtcggc
gcgtatgctcgcgaccaaggcatcgaagcggcttattttgtcggcgacaacagcgtcgaa
gcggcggaaaaatttggcgcggacggtttgtggttcgccgccaaagacccgttgattcaa
gtgttgcgccacgatttgcccgaacgcgccaccgtgttggtgaaaggttcgcgctttatg
cagatggaagaagtggtcgaggcattggaggataagtga
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