KEGG   PATHWAY: atf00630
Entry
atf00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Agrobacterium tumefaciens Ach5
Class
Metabolism; Carbohydrate metabolism
Pathway map
atf00630  Glyoxylate and dicarboxylate metabolism
atf00630

Module
atf_M00012  Glyoxylate cycle [PATH:atf00630]
atf_M00621  Glycine cleavage system [PATH:atf00630]
atf_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:atf00630]
Other DBs
GO: 0046487 0043648
Organism
Agrobacterium tumefaciens Ach5 [GN:atf]
Gene
Ach5_05320  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
Ach5_26290  acs; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
Ach5_48360  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
Ach5_00470  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
Ach5_25240  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
Ach5_12880  cisY; citrate synthase [KO:K01647] [EC:2.3.3.1]
Ach5_25710  acnA; aconitate hydratase [KO:K01681] [EC:4.2.1.3]
Ach5_40300  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
Ach5_33340  atoB; acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
Ach5_26520  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Ach5_04290  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Ach5_48330  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Ach5_27820  acaB; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
Ach5_26530  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
Ach5_34270  gloA; lactoylglutathione lyase [KO:K05606] [EC:5.1.99.1]
Ach5_34290  pccA; propionyl-coenzyme A carboxylase, alpha polypeptide [KO:K01965] [EC:6.4.1.3]
Ach5_34330  pccB; propionyl-CoA carboxylase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
Ach5_36930  biotin carboxylase [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
Ach5_34280  mutA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
Ach5_05850  glcD; glycolate oxidase subunit [KO:K00104] [EC:1.1.99.14]
Ach5_05870  glcE; glycolate oxidase subunit [KO:K11472] [EC:1.1.99.14]
Ach5_05880  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
Ach5_44480  catE; catalase C [KO:K03781] [EC:1.11.1.6]
Ach5_00670  D-isomer specific 2-hydroxyacid dehydrogenases family protein [KO:K00015] [EC:1.1.1.26]
Ach5_32600  2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Ach5_38280  2-hydroxyacid dehydrogenase [KO:K12972] [EC:1.1.1.79 1.1.1.81]
Ach5_15460  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Ach5_52900  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
Ach5_13380  hydrolase [KO:K01091] [EC:3.1.3.18]
Ach5_06190  phosphatase [KO:K01091] [EC:3.1.3.18]
Ach5_16970  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Ach5_01770  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Ach5_20250  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Ach5_05270  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Ach5_22830  glnA; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
Ach5_40930  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Ach5_10800  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
Ach5_13280  gcvP; glycine cleavage system protein P2 [KO:K00281] [EC:1.4.4.2]
Ach5_13300  gcvT; glycine cleavage system T protein, aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
Ach5_25170  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Ach5_13000  lpdA; dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
Ach5_13290  gcvH; glycine cleavage system component H [KO:K02437]
Ach5_49450  glycerate kinase [KO:K00865] [EC:2.7.1.165]
Ach5_30780  ttuD; hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
Ach5_32640  3-isopropylmalate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
Ach5_41900  kdgA; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
Ach5_39720  oxdD; oxalate decarboxylase [KO:K01569] [EC:4.1.1.2]
Ach5_44320  fdsD; NAD-dependent formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
Ach5_44310  fdhF; formate dehydrogenase alpha subunit [KO:K00123] [EC:1.17.1.9]
Ach5_44300  nuoF; NADH ubiquinone oxidoreductase chain F [KO:K00124]
Ach5_44290  nuoE; NADH ubiquinone oxidoreductase chain E [KO:K00127]
Ach5_40940  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Ach5_23320  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Ach5_36140  formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Ach5_37100  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
atf00010  Glycolysis / Gluconeogenesis
atf00020  Citrate cycle (TCA cycle)
atf00030  Pentose phosphate pathway
atf00053  Ascorbate and aldarate metabolism
atf00071  Fatty acid degradation
atf00230  Purine metabolism
atf00250  Alanine, aspartate and glutamate metabolism
atf00260  Glycine, serine and threonine metabolism
atf00620  Pyruvate metabolism
atf00750  Vitamin B6 metabolism
atf00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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