KEGG   PATHWAY: bpsd00630
Entry
bpsd00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Burkholderia pseudomallei MSHR520
Class
Metabolism; Carbohydrate metabolism
Pathway map
bpsd00630  Glyoxylate and dicarboxylate metabolism
bpsd00630

Module
bpsd_M00012  Glyoxylate cycle [PATH:bpsd00630]
bpsd_M00621  Glycine cleavage system [PATH:bpsd00630]
Other DBs
GO: 0046487 0043648
Organism
Burkholderia pseudomallei MSHR520 [GN:bpsd]
Gene
BBX_1761  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
BBX_5452  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
BBX_2574  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BBX_5682  AMP-binding enzyme family protein [KO:K01895] [EC:6.2.1.1]
BBX_1757  aceB; malate synthase A [KO:K01638] [EC:2.3.3.9]
BBX_4242  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
BBX_4235  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
BBX_3083  citrate synthase family protein [KO:K01647] [EC:2.3.3.1]
BBX_4246  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
BBX_1906  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBX_273  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBX_2018  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBX_2024  acetyl-CoA C-acetyltransferase family protein [KO:K00626] [EC:2.3.1.9]
BBX_4486  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BBX_2019  phbB-1; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
BBX_1000  FAD binding domain protein [KO:K00104] [EC:1.1.99.14]
BBX_999  FAD binding domain protein [KO:K11472] [EC:1.1.99.14]
BBX_998  4Fe-4S binding domain protein [KO:K11473] [EC:1.1.99.14]
BBX_6128  katB; catalase [KO:K03781] [EC:1.11.1.6]
BBX_263  catalase family protein [KO:K03781] [EC:1.11.1.6]
BBX_4853  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
BBX_37  ghrA; glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
BBX_2062  ghrB; glyoxylate/hydroxypyruvate reductase B [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BBX_1383  NADP oxidoreductase coenzyme F420-dependent family protein [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
BBX_763  gph; phosphoglycolate phosphatase, bacterial [KO:K01091] [EC:3.1.3.18]
BBX_1392  HAD hydrolase, IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
BBX_5534  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BBX_1555  glutamine synthetase, catalytic domain protein [KO:K01915] [EC:6.3.1.2]
BBX_1572  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
BBX_1086  beta-eliminating lyase family protein [KO:K00600] [EC:2.1.2.1]
BBX_5612  glyA2; serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
BBX_407  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
BBX_409  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
BBX_2379  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BBX_4913  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BBX_1592  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
BBX_408  gcvH; glycine cleavage system H protein [KO:K02437]
BBX_1933  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
BBX_1932  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
BBX_1930  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
BBX_1878  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BBX_5184  glycerate kinase family protein [KO:K00865] [EC:2.7.1.165]
BBX_5011  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
BBX_906  eda; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein [KO:K01625] [EC:4.1.2.14 4.1.3.42]
BBX_6099  oxdD; oxalate decarboxylase oxdD [KO:K01569] [EC:4.1.1.2]
BBX_1306  NADH-dependent formate dehydrogenase delta subunit FdsD family protein [KO:K00126] [EC:1.17.1.9]
BBX_1307  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BBX_4183  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
BBX_4184  Tat (twin-arginine translocation) pathway signal sequence domain protein [KO:K00123] [EC:1.17.1.9]
BBX_4182  fdxH; formate dehydrogenase, beta subunit [KO:K00124]
BBX_1308  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein [KO:K00124]
BBX_4181  formate dehydrogenase, gamma subunit [KO:K00127]
BBX_1309  respiratory-chain NADH dehydrogenase 24 Kd subunit [KO:K00127]
BBX_2532  alpha/beta hydrolase fold family protein [KO:K01432] [EC:3.5.1.9]
BBX_3125  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
BBX_3382  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BBX_5623  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
BBX_1552  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
bpsd00010  Glycolysis / Gluconeogenesis
bpsd00020  Citrate cycle (TCA cycle)
bpsd00030  Pentose phosphate pathway
bpsd00053  Ascorbate and aldarate metabolism
bpsd00071  Fatty acid degradation
bpsd00230  Purine metabolism
bpsd00250  Alanine, aspartate and glutamate metabolism
bpsd00260  Glycine, serine and threonine metabolism
bpsd00620  Pyruvate metabolism
bpsd00710  Carbon fixation in photosynthetic organisms
bpsd00750  Vitamin B6 metabolism
bpsd00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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