KEGG   PATHWAY: hezz00630
Entry
hezz00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Halorubrum ezzemoulense
Class
Metabolism; Carbohydrate metabolism
Pathway map
hezz00630  Glyoxylate and dicarboxylate metabolism
hezz00630

Module
hezz_M00621  Glycine cleavage system [PATH:hezz00630]
hezz_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:hezz00630]
hezz_M00968  Pentose bisphosphate pathway (nucleoside degradation), archaea, nucleoside/NMP => 3-PGA/glycerone phosphate [PATH:hezz00630]
Other DBs
GO: 0046487 0043648
Organism
Halorubrum ezzemoulense [GN:hezz]
Gene
EO776_10965  isocitrate lyase/PEP mutase family protein [KO:K01637] [EC:4.1.3.1]
EO776_08075  acetyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
EO776_07570  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
EO776_07580  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
EO776_15360  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EO776_04755  citrate synthase [KO:K01647] [EC:2.3.3.1]
EO776_00570  aconitate hydratase [KO:K01681] [EC:4.2.1.3]
EO776_07305  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EO776_16200  thiolase domain-containing protein [KO:K00626] [EC:2.3.1.9]
EO776_04290  thiolase family protein [KO:K00626] [EC:2.3.1.9]
EO776_09530  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
EO776_07345  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
EO776_16250  VOC family protein [KO:K05606] [EC:5.1.99.1]
EO776_14630  ATP-grasp domain-containing protein [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
EO776_14645  acyl-CoA carboxylase subunit beta [KO:K19312] [EC:6.4.1.2 6.4.1.3 2.1.3.15]
EO776_14640  hypothetical protein [KO:K22568] [EC:6.4.1.2 6.4.1.3]
EO776_03235  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
EO776_07355  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
EO776_05550  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
EO776_13470  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EO776_16750  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EO776_10350  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EO776_06305  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EO776_10180  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
EO776_06300  HAD-IIB family hydrolase [KO:K22223] [EC:3.1.3.18]
EO776_07035  alanine--glyoxylate aminotransferase family protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
EO776_04990  glutamate synthase large subunit [KO:K00284] [EC:1.4.7.1]
EO776_13210  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
EO776_12440  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
EO776_10515  aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
EO776_10510  glycine dehydrogenase subunit 2 [KO:K00283] [EC:1.4.4.2]
EO776_07765  glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
EO776_03045  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
EO776_00700  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EO776_10520  gcvH; glycine cleavage system protein GcvH [KO:K02437]
EO776_02710  DUF4147 domain-containing protein [KO:K11529] [EC:2.7.1.165]
EO776_12590  HAD family hydrolase [KO:K26210] [EC:3.1.3.109]
EO776_12585  class II aldolase/adducin family protein [KO:K01636] [EC:4.1.2.-]
EO776_01580  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EO776_00730  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EO776_07700  ACT domain-containing protein [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
hezz00010  Glycolysis / Gluconeogenesis
hezz00020  Citrate cycle (TCA cycle)
hezz00030  Pentose phosphate pathway
hezz00053  Ascorbate and aldarate metabolism
hezz00071  Fatty acid degradation
hezz00230  Purine metabolism
hezz00250  Alanine, aspartate and glutamate metabolism
hezz00260  Glycine, serine and threonine metabolism
hezz00620  Pyruvate metabolism
hezz00750  Vitamin B6 metabolism
hezz00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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