KEGG   PATHWAY: hsyr00062
Entry
hsyr00062                   Pathway                                
Name
Fatty acid elongation - Hibiscus syriacus (Rose-of-Sharon)
Class
Metabolism; Lipid metabolism
Pathway map
hsyr00062  Fatty acid elongation
hsyr00062

Module
hsyr_M00415  Fatty acid elongation in endoplasmic reticulum [PATH:hsyr00062]
Other DBs
GO: 0030497
Organism
Hibiscus syriacus (Rose-of-Sharon) [GN:hsyr]
Gene
120160066  LOW QUALITY PROTEIN: enoyl-[acyl-carrier-protein] reductase, mitochondrial-like [KO:K07512] [EC:1.3.1.- 1.3.1.38]
120114119  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
120201490  palmitoyl-protein thioesterase 3-like [KO:K01074] [EC:3.1.2.22]
120155109  palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
120173051  palmitoyl-protein thioesterase 1-like isoform X1 [KO:K01074] [EC:3.1.2.22]
120161001  LOW QUALITY PROTEIN: palmitoyl-protein thioesterase 1-like [KO:K01074] [EC:3.1.2.22]
120162160  3-ketoacyl-CoA synthase 10-like [KO:K15397] [EC:2.3.1.199]
120147061  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
120180034  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
120213851  3-ketoacyl-CoA synthase 11-like isoform X1 [KO:K15397] [EC:2.3.1.199]
120198736  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
120214838  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
120116676  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
120182952  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120117660  3-ketoacyl-CoA synthase 10-like [KO:K15397] [EC:2.3.1.199]
120150636  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
120216630  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
120134618  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
120134923  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
120135349  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120151560  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
120167534  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
120201530  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120201544  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120201722  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
120186257  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120218629  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
120218866  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
120139424  3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
120156161  3-ketoacyl-CoA synthase 19-like isoform X1 [KO:K15397] [EC:2.3.1.199]
120171435  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
120171767  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
120188909  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120205579  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120191270  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
120207176  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120158464  3-ketoacyl-CoA synthase 1-like [KO:K15397] [EC:2.3.1.199]
120174998  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
120191525  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
120192247  LOW QUALITY PROTEIN: 3-ketoacyl-CoA synthase 11-like [KO:K15397] [EC:2.3.1.199]
120209231  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
120160454  3-ketoacyl-CoA synthase 9-like [KO:K15397] [EC:2.3.1.199]
120194095  3-ketoacyl-CoA synthase 12-like [KO:K15397] [EC:2.3.1.199]
120145582  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
120178608  3-ketoacyl-CoA synthase 4-like [KO:K15397] [EC:2.3.1.199]
120149483  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120182647  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120117990  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120134699  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120170780  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120124856  very-long-chain 3-oxoacyl-CoA reductase-like protein At1g24470 [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120211552  very-long-chain 3-oxoacyl-CoA reductase 1-like [KO:K10251] [EC:1.1.1.62 1.1.1.330]
120119319  LOW QUALITY PROTEIN: very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2-like [KO:K10703] [EC:4.2.1.134]
120202171  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2-like [KO:K10703] [EC:4.2.1.134]
120206853  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2-like [KO:K10703] [EC:4.2.1.134]
120213300  very-long-chain enoyl-CoA reductase-like [KO:K10258] [EC:1.3.1.93]
120115438  very-long-chain enoyl-CoA reductase-like [KO:K10258] [EC:1.3.1.93]
120181547  acyl-CoA thioesterase 2-like isoform X1 [KO:K01068] [EC:3.1.2.2]
120136035  acyl-CoA thioesterase 2-like isoform X1 [KO:K01068] [EC:3.1.2.2]
120126036  acyl-CoA thioesterase 2-like isoform X1 [KO:K01068] [EC:3.1.2.2]
120208450  acyl-CoA thioesterase 2-like isoform X1 [KO:K01068] [EC:3.1.2.2]
Compound
C00024  Acetyl-CoA
C00040  Acyl-CoA
C00083  Malonyl-CoA
C00136  Butanoyl-CoA
C00154  Palmitoyl-CoA
C00162  Fatty acid
C00249  Hexadecanoic acid
C00264  3-Oxoacyl-CoA
C00605  2,3-Dehydroacyl-CoA
C00638  Long-chain fatty acid
C00640  (3S)-3-Hydroxyacyl-CoA
C00658  trans-2,3-Dehydroacyl-CoA
C01832  Lauroyl-CoA
C01944  Octanoyl-CoA
C02593  Tetradecanoyl-CoA
C02843  Long-chain acyl-CoA
C03221  2-trans-Dodecenoyl-CoA
C05258  (S)-3-Hydroxyhexadecanoyl-CoA
C05259  3-Oxopalmitoyl-CoA
C05260  (S)-3-Hydroxytetradecanoyl-CoA
C05261  3-Oxotetradecanoyl-CoA
C05262  (S)-3-Hydroxydodecanoyl-CoA
C05263  3-Oxododecanoyl-CoA
C05264  (S)-Hydroxydecanoyl-CoA
C05265  3-Oxodecanoyl-CoA
C05266  (S)-3-Hydroxyoctanoyl-CoA
C05267  3-Oxooctanoyl-CoA
C05268  (S)-Hydroxyhexanoyl-CoA
C05269  3-Oxohexanoyl-CoA
C05270  Hexanoyl-CoA
C05271  trans-Hex-2-enoyl-CoA
C05272  trans-Hexadec-2-enoyl-CoA
C05273  trans-Tetradec-2-enoyl-CoA
C05274  Decanoyl-CoA
C05275  trans-Dec-2-enoyl-CoA
C05276  trans-Oct-2-enoyl-CoA
C20876  Very-long-chain acyl-CoA
C20877  Very-long-chain 3-oxoacyl-CoA
C20878  Very-long-chain (3R)-3-hydroxyacyl-CoA
C20879  Very-long-chain trans-2,3-dehydroacyl-CoA
Reference
PMID:4387390
  Authors
Seubert W, Lamberts I, Kramer R, Ohly B
  Title
On the mechanism of malonyl-CoA-independent fatty acid synthesis. I. The mechanism of elongation of long-chain fatty acids by acetyl-CoA.
  Journal
Biochim Biophys Acta 164:498-517 (1968)
DOI:10.1016/0005-2760(68)90180-X
Reference
PMID:7150615
  Authors
El-Fakhri M, Middleton B
  Title
The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria.
  Journal
Biochim Biophys Acta 713:270-9 (1982)
DOI:10.1016/0005-2760(82)90244-2
Reference
PMID:8190743
  Authors
Cassagne C, Lessire R, Bessoule JJ, Moreau P, Creach A, Schneider F, Sturbois B
  Title
Biosynthesis of very long chain fatty acids in higher plants.
  Journal
Prog Lipid Res 33:55-69 (1994)
DOI:10.1016/0163-7827(94)90009-4
Reference
PMID:16564093
  Authors
Jakobsson A, Westerberg R, Jacobsson A.
  Title
Fatty acid elongases in mammals: their regulation and roles in metabolism.
  Journal
Prog Lipid Res 45:237-49 (2006)
DOI:10.1016/j.plipres.2006.01.004
Reference
PMID:16765910
  Authors
Blacklock BJ, Jaworski JG
  Title
Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.
  Journal
Biochem Biophys Res Commun 346:583-90 (2006)
DOI:10.1016/j.bbrc.2006.05.162
Reference
PMID:16866954
  Authors
Shepherd T, Wynne Griffiths D
  Title
The effects of stress on plant cuticular waxes.
  Journal
New Phytol 171:469-99 (2006)
DOI:10.1111/j.1469-8137.2006.01826.x
Reference
PMID:17719534
  Authors
Riezman H
  Title
The long and short of fatty acid synthesis.
  Journal
Cell 130:587-8 (2007)
DOI:10.1016/j.cell.2007.08.008
Reference
PMID:19649180
  Authors
Raffaele S, Leger A, Roby D
  Title
Very long chain fatty acid and lipid signaling in the response of plants to pathogens.
  Journal
Plant Signal Behav 4:94-9 (2009)
DOI:10.4161/psb.4.2.7580
Related
pathway
hsyr00071  Fatty acid degradation
hsyr00073  Cutin, suberine and wax biosynthesis
KO pathway
ko00062   
LinkDB

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