KEGG   PATHWAY: mnb04070
Entry
mnb04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Merops nubicus (carmine bee-eater)
Class
Environmental Information Processing; Signal transduction
Pathway map
mnb04070  Phosphatidylinositol signaling system
mnb04070

Organism
Merops nubicus (carmine bee-eater) [GN:mnb]
Gene
103782298  PI4KA; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
103775285  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
103770366  PI4K2B; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
103775824  SACM1L; phosphatidylinositide phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
103779928  phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
103776087  LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68]
103776654  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [KO:K00889] [EC:2.7.1.68]
103772705  phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
103775006  LOW QUALITY PROTEIN: inositol polyphosphate 5-phosphatase OCRL-1-like [KO:K01099] [EC:3.1.3.36]
103769862  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase [KO:K01099] [EC:3.1.3.36]
103779770  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
103767970  SYNJ1; LOW QUALITY PROTEIN: synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
103779125  SYNJ2; synaptojanin-2 [KO:K20279] [EC:3.1.3.36]
103780557  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
103781787  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
103778679  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103768794  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
103776111  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
103782078  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
103782183  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
103775983  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
103771581  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
103769718  MTM1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
103769669  MTMR2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
103782168  MTMR1; myotubularin-related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
103773620  MTMR3; myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
103774824  MTMR4; LOW QUALITY PROTEIN: myotubularin-related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
103774519  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
103769808  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
103777102  MTMR7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
103775485  MTMR14; myotubularin-related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
103781857  phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
103778248  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
103774163  TMEM55A; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
103771024  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
103770637  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
103772360  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
103779156  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
103781733  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
103771006  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
103768638  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [KO:K05857] [EC:3.1.4.11]
103772394  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4-like [KO:K05857] [EC:3.1.4.11]
103779299  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
103772869  PLCG2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
103772359  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
103778933  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
103781720  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
103775268  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
103779559  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
103781804  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
103770035  IP6K1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
103778103  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
103779687  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1-like [KO:K13024] [EC:2.7.4.24]
103777674  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 [KO:K13024] [EC:2.7.4.24]
103771853  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
103778976  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
103779876  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
103779886  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
103782309  DGKK; LOW QUALITY PROTEIN: diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
103777046  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
103777598  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
103772633  diacylglycerol kinase eta-like [KO:K00901] [EC:2.7.1.107]
103772792  diacylglycerol kinase beta-like [KO:K00901] [EC:2.7.1.107]
103773888  phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
103771576  phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
103772908  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
103779350  protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
103778180  LOW QUALITY PROTEIN: protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
103779262  calmodulin [KO:K02183]
103779369  calmodulin-alpha-like [KO:K02183]
103778758  CALML4; calmodulin-like protein 4 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
mnb04020  Calcium signaling pathway
mnb04144  Endocytosis
mnb04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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