KEGG   PATHWAY: ngi03082
Entry
ngi03082                    Pathway                                
Name
ATP-dependent chromatin remodeling - Nannospalax galili (Upper Galilee mountains blind mole rat)
Class
Genetic Information Processing; Chromosome
Pathway map
ngi03082  ATP-dependent chromatin remodeling
ngi03082

Organism
Nannospalax galili (Upper Galilee mountains blind mole rat) [GN:ngi]
Gene
103742389  Smarca5; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 [KO:K11654] [EC:5.6.2.-]
103731420  Baz1a; bromodomain adjacent to zinc finger domain 1A [KO:K11655]
103746252  Baz1b; bromodomain adjacent to zinc finger domain 1B [KO:K11658]
103730214  Baz2a; bromodomain adjacent to zinc finger domain 2A [KO:K15224]
103728721  bromodomain adjacent to zinc finger domain protein 2B [KO:K26167]
103748423  Chrac1; chromatin accessibility complex 1 [KO:K11656]
103734520  Pole3; DNA polymerase epsilon 3, accessory subunit [KO:K02326] [EC:2.7.7.7]
103743003  Rsf1; remodeling and spacing factor 1 [KO:K11657]
103728745  Smarca1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 [KO:K11727] [EC:5.6.2.-]
103740930  Bptf; bromodomain PHD finger transcription factor [KO:K11728]
103730891  Rbbp4; RB binding protein 4, chromatin remodeling factor [KO:K10752]
103749344  Rbbp7; RB binding protein 7, chromatin remodeling factor [KO:K11659]
103752171  CUNH17orf49; chromosome unknown C17orf49 homolog [KO:K23406]
103745891  Cecr2; cat eye syndrome critical region protein 2 [KO:K25830]
103752235  Chd3; chromodomain helicase DNA binding protein 3 [KO:K11642] [EC:5.6.2.-]
103727520  Chd4; chromodomain helicase DNA binding protein 4 [KO:K11643] [EC:5.6.2.-]
103733778  Hdac2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
103745919  Hdac1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
103736214  Mbd2; methyl-CpG binding domain protein 2 [KO:K11590]
103737316  Mbd3; methyl-CpG binding domain protein 3 [KO:K11591]
103736389  Mta3; metastasis associated 1 family member 3 [KO:K11660]
103737685  Mta2; metastasis associated 1 family member 2 [KO:K11660]
103724400  Mta1; metastasis associated 1 [KO:K11660]
103726836  Gatad2a; GATA zinc finger domain containing 2A [KO:K23194]
103751738  Gatad2b; GATA zinc finger domain containing 2B [KO:K23194]
103728777  Phf6; PHD finger protein 6 [KO:K23310]
103738201  cyclin-dependent kinase 2-associated protein 1 [KO:K26454]
103739035  Cdk2ap1; cyclin dependent kinase 2 associated protein 1 [KO:K26454]
103725595  Cdk2ap2; cyclin dependent kinase 2 associated protein 2 [KO:K26455]
103734566  Smarca4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 [KO:K11647] [EC:5.6.2.-]
103740070  Smarcb1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 [KO:K11648]
103732182  Smarcc1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 [KO:K11649]
103746508  Smarcc2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2 [KO:K11649]
103745317  Smarcd3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 [KO:K11650]
103744749  Smarcd2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 [KO:K11650]
103746542  Smarcd1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 [KO:K11650]
103735814  Smarce1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 [KO:K11651]
103750271  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-like [KO:K11651]
103730387  Actg1; actin gamma 1 [KO:K05692]
103748659  Actb; actin beta [KO:K05692]
103738591  Actl6a; actin like 6A [KO:K11340]
103733510  Actl6b; actin like 6B [KO:K11652]
103746254  Bcl7b; BCL tumor suppressor 7B [KO:K25605]
103726341  Bcl7c; BCL tumor suppressor 7C [KO:K25605]
103739060  Bcl7a; BCL tumor suppressor 7A [KO:K25605]
103742231  Ss18l1; SS18L1, nBAF chromatin remodeling complex subunit [KO:K15623]
103745685  Ss18; SS18, nBAF chromatin remodeling complex subunit [KO:K15623]
103737119  Arid1a; AT-rich interaction domain 1A [KO:K11653]
103739322  Arid1b; AT-rich interaction domain 1B [KO:K11653]
103750701  Dpf1; double PHD fingers 1 [KO:K22198]
103747397  Dpf3; double PHD fingers 3 [KO:K22198]
103724981  Dpf2; double PHD fingers 2 [KO:K13196]
103740641  Arid2; AT-rich interaction domain 2 [KO:K11765]
103749007  Pbrm1; polybromo 1 [KO:K11757]
103730121  Brd7; bromodomain containing 7 [KO:K11723]
103742339  Phf10; PHD finger protein 10 [KO:K22197]
103749667  Brd9; bromodomain containing 9 [KO:K22184]
103725057  Gltscr1; glioma tumor suppressor candidate region gene 1 [KO:K25612]
103736266  Gltscr1l; GLTSCR1 like [KO:K25613]
103744927  Ino80; INO80 complex subunit [KO:K11665] [EC:5.6.2.-]
103726995  Ino80b; INO80 complex subunit B [KO:K11666]
103750587  Ino80c; INO80 complex subunit C [KO:K11667]
103744429  Ino80d; INO80 complex subunit D [KO:K11668]
103726379  Ino80e; INO80 complex subunit E [KO:K11669]
103729673  Tfpt; TCF3 fusion partner [KO:K11670]
103749256  Nfrkb; nuclear factor related to kappaB binding protein [KO:K11671]
103745595  Mcrs1; microspherule protein 1 [KO:K11674]
103736709  Uchl5; ubiquitin C-terminal hydrolase L5 [KO:K05610] [EC:3.4.19.12]
103730346  Ruvbl1; RuvB like AAA ATPase 1 [KO:K04499] [EC:5.6.2.4]
103743643  Ruvbl2; RuvB like AAA ATPase 2 [KO:K11338] [EC:5.6.2.3]
103747236  Actr5; ARP5 actin-related protein 5 homolog [KO:K11672]
103749027  Actr8; ARP8 actin-related protein 8 homolog [KO:K11673]
103727648  Yy1; YY1 transcription factor [KO:K09201]
103730147  Yy2; YY2 transcription factor [KO:K09201]
103726347  Srcap; Snf2 related CREBBP activator protein [KO:K11661] [EC:5.6.2.-]
103743871  Dmap1; DNA methyltransferase 1 associated protein 1 [KO:K11324]
103726235  Yeats4; YEATS domain containing 4 [KO:K11341]
103730073  Vps72; vacuolar protein sorting 72 homolog [KO:K11664]
103733143  histone H2A, sperm-like [KO:K11251]
103733127  histone H2A type 1-H-like [KO:K11251]
103733094  histone H2A type 1 [KO:K11251]
103733115  histone H2A type 1 [KO:K11251]
103733117  histone H2A type 1 [KO:K11251]
103733101  histone H2A type 1 [KO:K11251]
103733098  histone H2A type 1 [KO:K11251]
103733108  histone H2A type 1-like [KO:K11251]
103746136  core histone macro-H2A.1 [KO:K11251]
103734158  histone H2A-Bbd type 1-like [KO:K11251]
103728171  histone H2A-Bbd type 1-like [KO:K11251]
103734994  histone H2A.V [KO:K11251]
103742652  histone H2A type 2-B [KO:K11251]
103742651  histone H2A type 2-C [KO:K11251]
103742644  histone H2A type 2-A [KO:K11251]
103742646  histone H2A type 2-A-like [KO:K11251]
103746567  histone H2A-Bbd type 1-like [KO:K11251]
103747948  histone H2A-Bbd type 1-like [KO:K11251]
103747949  histone H2A-Bbd type 1-like [KO:K11251]
103749476  histone H2A type 1-D-like [KO:K11251]
103752318  histone H2A.J [KO:K11251]
103727888  histone H2AX [KO:K11251]
103728040  histone H2A.Z [KO:K11251]
103728660  histone H2A type 1 [KO:K11251]
103728663  histone H2A type 1-H [KO:K11251]
103728667  histone H2A type 1 [KO:K11251]
103728677  histone H2A type 1-like [KO:K11251]
103728668  histone H2A type 1-H [KO:K11251]
103728675  histone H2A type 1 [KO:K11251]
103729053  histone H2A type 3 [KO:K11251]
103729722  core histone macro-H2A.2 [KO:K11251]
103748501  Actr6; ARP6 actin-related protein 6 homolog [KO:K11662]
103733493  Znhit1; zinc finger HIT-type containing 1 [KO:K11663]
103750606  Ep400; E1A binding protein p400 [KO:K11320] [EC:5.6.2.-]
103726460  Trrap; transformation/transcription domain associated protein [KO:K08874]
103726017  Morf4l1; mortality factor 4 like 1 [KO:K11339]
103724511  mortality factor 4-like protein 1 [KO:K11339]
103740921  mortality factor 4-like protein 2 [KO:K11342]
103733568  Morf4l2; mortality factor 4 like 2 [KO:K11342]
103742243  Mrgbp; MRG domain binding protein [KO:K11343]
103735161  Brd8; bromodomain containing 8 [KO:K11321]
103730608  Ing3; inhibitor of growth family member 3 [KO:K11319]
103748006  Epc1; enhancer of polycomb homolog 1 [KO:K11322]
103727325  Epc2; enhancer of polycomb homolog 2 [KO:K11322]
103747687  Meaf6; MYST/Esa1 associated factor 6 [KO:K11344]
103724996  Kat5; lysine acetyltransferase 5 [KO:K11304] [EC:2.3.1.48]
Reference
  Authors
Hasan N, Ahuja N
  Title
The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer.
  Journal
Cancers (Basel) 11:cancers11121859 (2019)
DOI:10.3390/cancers11121859
Reference
  Authors
He S, Wu Z, Tian Y, Yu Z, Yu J, Wang X, Li J, Liu B, Xu Y
  Title
Structure of nucleosome-bound human BAF complex.
  Journal
Science 367:875-881 (2020)
DOI:10.1126/science.aaz9761
Reference
  Authors
Wanior M, Kramer A, Knapp S, Joerger AC
  Title
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy.
  Journal
Oncogene 40:3637-3654 (2021)
DOI:10.1038/s41388-021-01781-x
Reference
  Authors
Burgio G, Onorati MC, Corona DF
  Title
Chromatin remodeling regulation by small molecules and metabolites.
  Journal
Biochim Biophys Acta 1799:671-80 (2010)
DOI:10.1016/j.bbagrm.2010.05.007
KO pathway
ko03082   
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