KEGG   PATHWAY: nlu00230
Entry
nlu00230                    Pathway                                
Name
Purine metabolism - Nilaparvata lugens (brown planthopper)
Class
Metabolism; Nucleotide metabolism
Pathway map
nlu00230  Purine metabolism
nlu00230

Module
nlu_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:nlu00230]
nlu_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:nlu00230]
nlu_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:nlu00230]
nlu_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:nlu00230]
nlu_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:nlu00230]
nlu_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:nlu00230]
nlu_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:nlu00230]
Other DBs
GO: 0006163 0042278
Organism
Nilaparvata lugens (brown planthopper) [GN:nlu]
Gene
111061825  ADP-ribose pyrophosphatase, mitochondrial [KO:K13988] [EC:3.6.1.13]
111063230  LOW QUALITY PROTEIN: phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
111052301  glucose 1,6-bisphosphate synthase [KO:K15779] [EC:5.4.2.2 5.4.2.7]
111053456  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
111047646  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
111052553  trifunctional purine biosynthetic protein adenosine-3 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
111062983  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
111047647  multifunctional protein ADE2 [KO:K01587] [EC:4.1.1.21 6.3.2.6]
111050464  adenylosuccinate lyase isoform X1 [KO:K01756] [EC:4.3.2.2]
111051171  LOW QUALITY PROTEIN: bifunctional purine biosynthesis protein ATIC [KO:K00602] [EC:2.1.2.3 3.5.4.10]
111057292  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
111054526  cytosolic purine 5'-nucleotidase isoform X1 [KO:K01081] [EC:3.1.3.5]
111056372  trifunctional nucleotide phosphoesterase protein YfkN isoform X1 [KO:K01081] [EC:3.1.3.5]
111053791  protein 5NUC [KO:K19970] [EC:3.1.3.5]
111058258  protein 5NUC-like isoform X1 [KO:K19970] [EC:3.1.3.5]
111047307  purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
111043490  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
111057236  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
111045508  nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
111047491  nucleoside diphosphate kinase 7 isoform X1 [KO:K00940] [EC:2.7.4.6]
111048246  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
111064320  soluble calcium-activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
120348761  U8 snoRNA-decapping enzyme-like isoform X1 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
111055328  U8 snoRNA-decapping enzyme isoform X1 [KO:K16855] [EC:3.6.1.62 3.6.1.64]
111059233  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
111060901  xanthine dehydrogenase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111055221  xanthine dehydrogenase/oxidase isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111055387  xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111056736  probable aldehyde oxidase 2 isoform X3 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111047233  indole-3-acetaldehyde oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111057942  indole-3-acetaldehyde oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111048124  indole-3-acetaldehyde oxidase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111060252  bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
111054442  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
111055184  GMP reductase 2 [KO:K00364] [EC:1.7.1.7]
111051661  guanine deaminase-like [KO:K01487] [EC:3.5.4.3]
111055677  guanine deaminase [KO:K01487] [EC:3.5.4.3]
111060730  guanylate kinase isoform X1 [KO:K00942] [EC:2.7.4.8]
120355441  ribonucleoside-diphosphate reductase large chain-like [KO:K10807] [EC:1.17.4.1]
111045786  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
111047300  ribonucleoside-diphosphate reductase subunit M2 B [KO:K10808] [EC:1.17.4.1]
111047187  5'-deoxynucleotidase HDDC2 isoform X1 [KO:K07023] [EC:3.1.3.89]
111045781  deoxynucleoside kinase isoform X1 [KO:K05961] [EC:2.7.1.145]
111048849  deoxynucleoside kinase [KO:K05961] [EC:2.7.1.145]
111046890  exopolyphosphatase PRUNE1 isoform X1 [KO:K01514] [EC:3.6.1.11]
120349390  LOW QUALITY PROTEIN: adenylate cyclase-like [KO:K01768] [EC:4.6.1.1]
111062756  LOW QUALITY PROTEIN: Ca(2+)/calmodulin-responsive adenylate cyclase [KO:K08041] [EC:4.6.1.1]
111045768  adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
111048874  adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
111044161  LOW QUALITY PROTEIN: adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
111044266  adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
111052708  LOW QUALITY PROTEIN: adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
111049624  head-specific guanylate cyclase [KO:K12318] [EC:4.6.1.2]
111056761  guanylate cyclase soluble subunit beta-1 [KO:K12319] [EC:4.6.1.2]
111064132  LOW QUALITY PROTEIN: retinal guanylyl cyclase 1 [KO:K12322] [EC:4.6.1.2]
111062794  guanylate cyclase soluble subunit alpha-1-like [KO:K12323] [EC:4.6.1.2]
111057294  LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
111048211  atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
111064230  guanylate cyclase 32E [KO:K01769] [EC:4.6.1.2]
111054571  LOW QUALITY PROTEIN: soluble guanylate cyclase 88E-like [KO:K01769] [EC:4.6.1.2]
111056274  LOW QUALITY PROTEIN: guanylate cyclase 32E-like [KO:K01769] [EC:4.6.1.2]
111059783  LOW QUALITY PROTEIN: receptor-type guanylate cyclase Gyc76C [KO:K01769] [EC:4.6.1.2]
111050664  calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 [KO:K13755] [EC:3.1.4.17]
111062493  cGMP-dependent 3',5'-cyclic phosphodiesterase-like [KO:K18283] [EC:3.1.4.17]
120354297  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like [KO:K18283] [EC:3.1.4.17]
111064056  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta isoform X1 [KO:K13758]
111048284  cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [KO:K13763] [EC:3.1.4.35]
111049893  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
111053745  probable 3',5'-cyclic phosphodiesterase pde-5 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
111047370  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
111050734  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A [KO:K13298] [EC:3.1.4.17 3.1.4.35]
111045654  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 isoform X3 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
111046524  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
111044048  AMP deaminase 2 [KO:K01490] [EC:3.5.4.6]
111050541  adenosine kinase [KO:K00856] [EC:2.7.1.20]
111048717  adenosine kinase [KO:K00856] [EC:2.7.1.20]
111051391  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
111051984  adenosine deaminase isoform X1 [KO:K01488] [EC:3.5.4.4]
111049845  adenylate kinase [KO:K00939] [EC:2.7.4.3]
111062598  adenylate kinase 8 isoform X1 [KO:K00939] [EC:2.7.4.3]
120348701  adenylate kinase 8-like isoform X1 [KO:K00939] [EC:2.7.4.3]
120355954  adenylate kinase 8-like isoform X1 [KO:K00939] [EC:2.7.4.3]
111055899  adenylate kinase isoenzyme 1 isoform X1 [KO:K00939] [EC:2.7.4.3]
111056976  adenylate kinase 7 isoform X1 [KO:K00939] [EC:2.7.4.3]
111058666  adenylate kinase isoenzyme 6 [KO:K18532] [EC:2.7.4.3]
120348850  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
111048396  LOW QUALITY PROTEIN: GTP:AMP phosphotransferase AK3, mitochondrial [KO:K00944] [EC:2.7.4.10]
111043306  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
111044032  LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase [KO:K13293] [EC:3.1.4.53]
120356112  cAMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13293] [EC:3.1.4.53]
111045382  uncharacterized protein LOC111045382 isoform X1 [KO:K13293] [EC:3.1.4.53]
111046669  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1 [KO:K18437] [EC:3.1.4.53]
111053152  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase [KO:K13811] [EC:2.7.7.4 2.7.1.25]
111055219  uricase [KO:K00365] [EC:1.7.3.3]
111057618  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
nlu00030  Pentose phosphate pathway
nlu00220  Arginine biosynthesis
nlu00250  Alanine, aspartate and glutamate metabolism
nlu00260  Glycine, serine and threonine metabolism
nlu00340  Histidine metabolism
nlu00630  Glyoxylate and dicarboxylate metabolism
nlu00730  Thiamine metabolism
nlu00740  Riboflavin metabolism
nlu00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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