KEGG   PATHWAY: pnb00630
Entry
pnb00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Pseudomonas nunensis
Class
Metabolism; Carbohydrate metabolism
Pathway map
pnb00630  Glyoxylate and dicarboxylate metabolism
pnb00630

Module
pnb_M00621  Glycine cleavage system [PATH:pnb00630]
Other DBs
GO: 0046487 0043648
Organism
Pseudomonas nunensis [GN:pnb]
Gene
NK667_06630  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
NK667_10410  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
NK667_32365  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NK667_02845  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
NK667_30170  malate synthase G [KO:K01638] [EC:2.3.3.9]
NK667_18890  gltA; citrate synthase [KO:K01647] [EC:2.3.3.1]
NK667_17625  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
NK667_13910  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
NK667_07890  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NK667_10420  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
NK667_11185  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NK667_18200  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NK667_23840  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
NK667_11180  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
NK667_02505  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
NK667_15080  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
NK667_15580  methylaspartate mutase [KO:K19268] [EC:5.4.99.1]
NK667_15575  cobalamin-dependent protein [KO:K01846] [EC:5.4.99.1]
NK667_07730  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
NK667_07725  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
NK667_07720  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
NK667_06330  catalase family peroxidase [KO:K03781] [EC:1.11.1.6]
NK667_26910  katE; catalase HPII [KO:K03781] [EC:1.11.1.6]
NK667_30875  catalase [KO:K03781] [EC:1.11.1.6]
NK667_31980  katB; catalase KatB [KO:K03781] [EC:1.11.1.6]
NK667_09965  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
NK667_05240  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
NK667_22460  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
NK667_00430  2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
NK667_26780  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
NK667_30505  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
NK667_03530  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
NK667_07795  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_07975  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_10615  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_20135  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_25455  glnA; glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
NK667_28985  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_28995  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_03040  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
NK667_30040  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NK667_32030  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
NK667_28885  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
NK667_02315  gcvP; aminomethyl-transferring glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
NK667_28870  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
NK667_02305  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
NK667_14330  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK667_18855  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK667_27645  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
NK667_28875  gcvH; glycine cleavage system protein GcvH [KO:K02437]
NK667_02320  gcvH; glycine cleavage system protein GcvH [KO:K02437]
NK667_18960  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
NK667_18965  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
NK667_18970  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
NK667_10220  glycerate kinase [KO:K00865] [EC:2.7.1.165]
NK667_18975  glycerate kinase [KO:K11529] [EC:2.7.1.165]
NK667_14685  aldA; aldehyde dehydrogenase [KO:K07248] [EC:1.2.1.22 1.2.1.21]
NK667_09960  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
NK667_02480  bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
NK667_00995  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
NK667_11250  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
NK667_01000  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
NK667_11245  fdxH; formate dehydrogenase subunit beta [KO:K00124]
NK667_01005  formate dehydrogenase [KO:K00124]
NK667_11240  formate dehydrogenase subunit gamma [KO:K00127]
NK667_01010  formate dehydrogenase subunit gamma [KO:K00127]
NK667_30065  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
NK667_02090  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
NK667_15765  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
NK667_25340  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pnb00010  Glycolysis / Gluconeogenesis
pnb00020  Citrate cycle (TCA cycle)
pnb00030  Pentose phosphate pathway
pnb00053  Ascorbate and aldarate metabolism
pnb00071  Fatty acid degradation
pnb00230  Purine metabolism
pnb00250  Alanine, aspartate and glutamate metabolism
pnb00260  Glycine, serine and threonine metabolism
pnb00620  Pyruvate metabolism
pnb00710  Carbon fixation by Calvin cycle
pnb00750  Vitamin B6 metabolism
pnb00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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