KEGG   PATHWAY: ppno02024
Entry
ppno02024                   Pathway                                
Name
Quorum sensing - Pandoraea pnomenusa RB38
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
ppno02024  Quorum sensing
ppno02024

Other DBs
GO: 0009372
Organism
Pandoraea pnomenusa RB38 [GN:ppno]
Gene
DA70_06355  RNA-binding protein Hfq [KO:K03666]
DA70_18815  anthranilate synthase [KO:K01657] [EC:4.1.3.27]
DA70_18775  anthranilate synthase component II [KO:K01658] [EC:4.1.3.27]
DA70_23485  hypothetical protein [KO:K13061] [EC:2.3.1.184]
DA70_20985  phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
DA70_16660  flagellar transcriptional activator FlhD [KO:K02403]
DA70_16665  transcriptional activator FlhC [KO:K02402]
DA70_01595  DNA-binding response regulator [KO:K07667]
DA70_09895  dehydrogenase [KO:K02055]
DA70_09175  ABC transporter substrate-binding protein [KO:K02055]
DA70_04830  ABC transporter substrate-binding protein [KO:K02055]
DA70_01250  branched-chain amino acid ABC transporter substrate-binding protein [KO:K02055]
DA70_02095  spermidine/putrescine ABC transporter substrate-binding protein [KO:K02055]
DA70_24025  ABC transporter substrate-binding protein [KO:K02055]
DA70_21155  ABC transporter substrate-binding protein [KO:K02055]
DA70_20705  ABC transporter substrate-binding protein [KO:K02055]
DA70_09165  ABC transporter permease [KO:K02053]
DA70_24035  ABC transporter permease [KO:K02053]
DA70_24030  ABC transporter permease [KO:K02053]
DA70_01265  ABC transporter permease [KO:K02053]
DA70_02075  ABC transporter permease [KO:K02053]
DA70_21165  ABC transporter permease [KO:K02053]
DA70_20720  ABC transporter permease [KO:K02053]
DA70_09885  ABC transporter permease [KO:K02053 K02054]
DA70_04820  ABC transporter permease [KO:K02053 K02054]
DA70_09170  ABC transporter permease [KO:K02054]
DA70_01260  ABC transporter permease [KO:K02054]
DA70_02070  ABC transporter permease [KO:K02054]
DA70_21150  ABC transporter permease [KO:K02054]
DA70_20715  ABC transporter permease [KO:K02054]
DA70_09890  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DA70_09160  hypothetical protein [KO:K02052]
DA70_04825  ABC transporter [KO:K02052]
DA70_24040  ABC transporter ATP-binding protein [KO:K02052]
DA70_01255  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DA70_02065  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DA70_21160  Fe3+/spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DA70_20710  spermidine/putrescine ABC transporter ATP-binding protein [KO:K02052]
DA70_14185  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_15740  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_15125  ABC transporter substrate-binding protein [KO:K01999]
DA70_08350  ABC transporter permease [KO:K01999]
DA70_11655  ethanolamine utilization protein EutN [KO:K01999]
DA70_08125  ABC transporter permease [KO:K01999]
DA70_07645  ABC transporter substrate-binding protein [KO:K01999]
DA70_10745  leucine ABC transporter subunit substrate-binding protein LivK [KO:K01999]
DA70_10400  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_03440  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_04755  amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_23525  ABC transporter substrate-binding protein [KO:K01999]
DA70_01315  ABC transporter permease [KO:K01999]
DA70_00520  ABC transporter substrate-binding protein [KO:K01999]
DA70_23990  ABC transporter substrate-binding protein [KO:K01999]
DA70_17035  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_16550  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_16525  ABC transporter permease [KO:K01999]
DA70_21495  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_20085  ABC transporter permease [KO:K01999]
DA70_22925  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_01440  branched chain amino acid ABC transporter substrate-binding protein [KO:K01999]
DA70_01760  ABC transporter permease [KO:K01999]
DA70_15120  ABC transporter permease [KO:K01997]
DA70_15745  ABC transporter permease [KO:K01997]
DA70_11660  ABC transporter permease [KO:K01997]
DA70_08105  ABC transporter permease [KO:K01997]
DA70_07640  ABC transporter permease [KO:K01997]
DA70_10750  branched-chain amino acid transporter permease subunit LivH [KO:K01997]
DA70_04750  ABC transporter permease [KO:K01997]
DA70_23520  ABC transporter permease [KO:K01997]
DA70_01305  ABC transporter permease [KO:K01997]
DA70_00525  branched-chain amino acid ABC transporter permease [KO:K01997]
DA70_23980  ABC transporter permease [KO:K01997]
DA70_16560  ABC transporter permease [KO:K01997]
DA70_16530  ABC transporter permease [KO:K01997]
DA70_21500  ABC transporter permease [KO:K01997]
DA70_22930  ABC transporter permease [KO:K01997]
DA70_04745  ABC transporter [KO:K01995 K01998]
DA70_16565  hypothetical protein [KO:K01995 K01998]
DA70_22935  hypothetical protein [KO:K01995 K01998]
DA70_11665  ABC transporter [KO:K01995 K01996 K01998]
DA70_15115  ABC transporter permease [KO:K01998]
DA70_15750  ABC transporter permease [KO:K01998]
DA70_08100  ABC transporter permease [KO:K01998]
DA70_07635  amino acid ABC transporter [KO:K01998]
DA70_10755  livM; branched-chain amino acid ABC transporter permease [KO:K01998]
DA70_02935  ABC transporter permease [KO:K01998]
DA70_01310  ABC transporter permease [KO:K01998]
DA70_23975  ABC transporter permease [KO:K01998]
DA70_21505  ABC transporter ATP-binding protein [KO:K01998]
DA70_16535  ABC transporter permease [KO:K01998]
DA70_15110  ABC transporter ATP-binding protein [KO:K01995]
DA70_24685  ABC transporter ATP-binding protein [KO:K01995]
DA70_08115  ABC transporter ATP-binding protein [KO:K01995]
DA70_07630  ABC transporter ATP-binding protein [KO:K01995]
DA70_10760  livG; ABC transporter ATP-binding protein [KO:K01995]
DA70_02940  ABC transporter ATP-binding protein [KO:K01995]
DA70_23510  ABC transporter ATP-binding protein [KO:K01995]
DA70_01300  ABC transporter ATP-binding protein [KO:K01995]
DA70_00535  ABC transporter ATP-binding protein [KO:K01995]
DA70_23970  ABC transporter ATP-binding protein [KO:K01995]
DA70_16515  ABC transporter ATP-binding protein [KO:K01995]
DA70_21510  ABC transporter ATP-binding protein [KO:K01995]
DA70_15105  ABC transporter ATP-binding protein [KO:K01996]
DA70_15760  ABC transporter ATP-binding protein [KO:K01996]
DA70_08110  ABC transporter ATP-binding protein [KO:K01996]
DA70_07625  ABC transporter ATP-binding protein [KO:K01996]
DA70_10765  livF; ABC transporter ATP-binding protein [KO:K01996]
DA70_04740  ABC transporter ATP-binding protein [KO:K01996]
DA70_02945  ABC transporter ATP-binding protein [KO:K01996]
DA70_22940  ABC transporter ATP-binding protein [KO:K01996]
DA70_23505  ABC transporter ATP-binding protein [KO:K01996]
DA70_01320  ABC transporter ATP-binding protein [KO:K01996]
DA70_00540  livF; ABC transporter ATP-binding protein [KO:K01996]
DA70_23965  ABC transporter ATP-binding protein [KO:K01996]
DA70_21515  ABC transporter ATP-binding protein [KO:K01996]
DA70_16570  ABC transporter ATP-binding protein [KO:K01996]
DA70_16520  ABC transporter ATP-binding protein [KO:K01996]
DA70_23535  IclR family transcriptional regulator [KO:K20539]
DA70_23490  hypothetical protein [KO:K19666]
DA70_03530  inclusion body protein [KO:K20275]
DA70_02795  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DA70_23375  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DA70_01295  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DA70_21205  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
DA70_18435  AMP-dependent synthetase [KO:K01897] [EC:6.2.1.3]
DA70_01290  Crp/Fnr family transcriptional regulator [KO:K10914]
DA70_08170  GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
DA70_10720  riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
DA70_22510  multidrug transporter [KO:K18139]
DA70_23195  multidrug transporter [KO:K18139]
DA70_11195  ABC transporter substrate-binding protein [KO:K02035]
DA70_22750  ABC transporter substrate-binding protein [KO:K02035]
DA70_11190  peptide ABC transporter [KO:K02033]
DA70_22770  ABC transporter permease [KO:K02033]
DA70_11185  diguanylate cyclase [KO:K02034]
DA70_22765  peptide ABC transporter permease [KO:K02034]
DA70_11205  dppD; peptide ABC transporter ATP-binding protein [KO:K02031]
DA70_22760  methionine ABC transporter ATP-binding protein [KO:K02031]
DA70_22755  peptide ABC transporter ATP-binding protein [KO:K02032]
DA70_11200  oligopeptide ABC transporter ATP-binding protein [KO:K02032]
DA70_16295  membrane protein insertase YidC [KO:K03217]
DA70_17700  preprotein translocase subunit SecE [KO:K03073]
DA70_07035  preprotein translocase subunit SecG [KO:K03075]
DA70_17960  secY; preprotein translocase subunit SecY [KO:K03076]
DA70_11970  preprotein translocase subunit YajC [KO:K03210]
DA70_19035  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
DA70_13700  signal recognition particle-docking protein FtsY [KO:K03110]
DA70_13890  protein-export chaperone SecB [KO:K03071]
DA70_19175  signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
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Related
pathway
ppno02040  Flagellar assembly
KO pathway
ko02024   
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