KEGG   PATHWAY: pstg02024
Entry
pstg02024                   Pathway                                
Name
Quorum sensing - Phreatobacter stygius
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
pstg02024  Quorum sensing
pstg02024

Other DBs
GO: 0009372
Organism
Phreatobacter stygius [GN:pstg]
Gene
E8M01_31535  hfq; RNA chaperone Hfq [KO:K03666]
E8M01_18040  hypothetical protein [KO:K01657] [EC:4.1.3.27]
E8M01_32895  trpE; anthranilate synthase component I [KO:K01657] [EC:4.1.3.27]
E8M01_32900  aminodeoxychorismate/anthranilate synthase component II [KO:K01658] [EC:4.1.3.27]
E8M01_15640  3-deoxy-7-phosphoheptulonate synthase class II [KO:K01626] [EC:2.5.1.54]
E8M01_18865  PhzF family phenazine biosynthesis protein [KO:K06998] [EC:5.3.3.17]
E8M01_13620  response regulator [KO:K07667]
E8M01_26190  glutamate decarboxylase [KO:K01580] [EC:4.1.1.15]
E8M01_06735  extracellular solute-binding protein [KO:K02055]
E8M01_26500  ABC transporter substrate-binding protein [KO:K02055]
E8M01_07285  extracellular solute-binding protein [KO:K02055]
E8M01_07340  extracellular solute-binding protein [KO:K02055]
E8M01_07360  extracellular solute-binding protein [KO:K02055]
E8M01_23895  extracellular solute-binding protein [KO:K02055]
E8M01_25610  ABC transporter substrate-binding protein [KO:K02055]
E8M01_27445  extracellular solute-binding protein [KO:K02055]
E8M01_19890  ABC transporter substrate-binding protein [KO:K02055]
E8M01_18960  ABC transporter substrate-binding protein [KO:K02055]
E8M01_03080  ABC transporter substrate-binding protein [KO:K02055]
E8M01_20190  ABC transporter substrate-binding protein [KO:K02055]
E8M01_24940  ABC transporter substrate-binding protein [KO:K02055]
E8M01_25015  extracellular solute-binding protein [KO:K02055]
E8M01_24950  ABC transporter permease subunit [KO:K02053 K02054]
E8M01_06720  ABC transporter permease [KO:K02053]
E8M01_26485  ABC transporter permease [KO:K02053]
E8M01_07310  ABC transporter permease subunit [KO:K02053]
E8M01_23880  ABC transporter permease [KO:K02053]
E8M01_25600  ABC transporter permease [KO:K02053]
E8M01_27435  ABC transporter permease [KO:K02053]
E8M01_19900  ABC transporter permease [KO:K02053]
E8M01_18975  ABC transporter permease [KO:K02053]
E8M01_03075  ABC transporter permease [KO:K02053]
E8M01_20205  ABC transporter permease [KO:K02053]
E8M01_25025  ABC transporter permease [KO:K02053]
E8M01_06725  ABC transporter permease [KO:K02054]
E8M01_26490  ABC transporter permease [KO:K02054]
E8M01_07315  sugar ABC transporter permease [KO:K02054]
E8M01_23885  ABC transporter permease [KO:K02054]
E8M01_25605  ABC transporter permease [KO:K02054]
E8M01_27440  ABC transporter permease [KO:K02054]
E8M01_19895  ABC transporter permease [KO:K02054]
E8M01_18970  ABC transporter permease [KO:K02054]
E8M01_03070  ABC transporter permease [KO:K02054]
E8M01_20200  ABC transporter permease [KO:K02054]
E8M01_25010  ABC transporter permease [KO:K02054]
E8M01_07320  ABC transporter ATP-binding protein [KO:K02052]
E8M01_27430  ABC transporter ATP-binding protein [KO:K02052]
E8M01_19885  ABC transporter ATP-binding protein [KO:K02052]
E8M01_18980  ABC transporter ATP-binding protein [KO:K02052]
E8M01_03065  ABC transporter ATP-binding protein [KO:K02052]
E8M01_20210  ABC transporter ATP-binding protein [KO:K02052]
E8M01_24945  ABC transporter ATP-binding protein [KO:K02052]
E8M01_25020  ABC transporter ATP-binding protein [KO:K02052]
E8M01_26495  ABC transporter ATP-binding protein [KO:K02052]
E8M01_25595  ABC transporter ATP-binding protein [KO:K02052]
E8M01_12875  ABC transporter substrate-binding protein [KO:K01999]
E8M01_13660  ABC transporter substrate-binding protein [KO:K01999]
E8M01_31315  ABC transporter substrate-binding protein [KO:K01999]
E8M01_33825  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_23590  ABC transporter substrate-binding protein [KO:K01999]
E8M01_27885  ABC transporter substrate-binding protein [KO:K01999]
E8M01_28795  ABC transporter substrate-binding protein [KO:K01999]
E8M01_28895  ABC transporter substrate-binding protein [KO:K01999]
E8M01_11220  ABC transporter substrate-binding protein [KO:K01999]
E8M01_00560  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_11460  ABC transporter substrate-binding protein [KO:K01999]
E8M01_32445  ABC transporter substrate-binding protein [KO:K01999]
E8M01_08085  ABC transporter permease [KO:K01999]
E8M01_06310  ABC transporter substrate-binding protein [KO:K01999]
E8M01_08360  ABC transporter permease [KO:K01999]
E8M01_14225  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_15380  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_17570  ABC transporter substrate-binding protein [KO:K01999]
E8M01_27550  ABC transporter substrate-binding protein [KO:K01999]
E8M01_24800  ABC transporter substrate-binding protein [KO:K01999]
E8M01_14450  hypothetical protein [KO:K01999]
E8M01_17925  ABC transporter substrate-binding protein [KO:K01999]
E8M01_18090  ABC transporter substrate-binding protein [KO:K01999]
E8M01_18235  twin-arginine translocation pathway signal protein [KO:K01999]
E8M01_07815  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_02560  ABC transporter substrate-binding protein [KO:K01999]
E8M01_14805  ABC transporter substrate-binding protein [KO:K01999]
E8M01_19525  branched-chain amino acid ABC transporter [KO:K01999]
E8M01_19925  ABC transporter substrate-binding protein [KO:K01999]
E8M01_20010  hypothetical protein [KO:K01999]
E8M01_22365  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_18830  ABC transporter substrate-binding protein [KO:K01999]
E8M01_20710  ABC transporter substrate-binding protein [KO:K01999]
E8M01_25730  ABC transporter substrate-binding protein [KO:K01999]
E8M01_28445  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_28555  ABC transporter substrate-binding protein [KO:K01999]
E8M01_20840  twin-arginine translocation pathway signal protein [KO:K01999]
E8M01_03110  ABC transporter substrate-binding protein [KO:K01999]
E8M01_03310  ABC transporter substrate-binding protein [KO:K01999]
E8M01_03315  ABC transporter substrate-binding protein [KO:K01999]
E8M01_03320  ABC transporter substrate-binding protein [KO:K01999]
E8M01_03325  ABC transporter substrate-binding protein [KO:K01999]
E8M01_09300  ABC transporter substrate-binding protein [KO:K01999]
E8M01_24905  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_21560  ABC transporter substrate-binding protein [KO:K01999]
E8M01_09610  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_09615  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_21630  ABC transporter substrate-binding protein [KO:K01999]
E8M01_14175  ABC transporter substrate-binding protein [KO:K01999]
E8M01_23440  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_01660  ABC transporter substrate-binding protein [KO:K01999]
E8M01_01990  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_30820  amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_03240  ABC transporter substrate-binding protein [KO:K01999]
E8M01_03590  ABC transporter substrate-binding protein [KO:K01999]
E8M01_13200  ABC transporter substrate-binding protein [KO:K01999]
E8M01_22730  branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
E8M01_13225  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_22740  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_33820  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_23595  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_27890  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_28790  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_28890  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_11225  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_00535  branched-chain amino acid ABC transporter permease LivH [KO:K01997]
E8M01_32450  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_08070  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_06305  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_08370  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_14195  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_14220  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_15385  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_17565  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_27545  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_24805  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_14455  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_17920  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_18085  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_18240  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_07810  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_02565  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_14800  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_20015  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_18825  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_20705  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_20835  ABC transporter permease [KO:K01997 K01998]
E8M01_01985  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_25735  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_28440  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_28560  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_19530  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_03105  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_03225  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_09295  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_23445  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_24910  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_21555  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_03595  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_09600  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_13735  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_01650  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_22360  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_27055  branched-chain amino acid ABC transporter permease [KO:K01997]
E8M01_18080  ATP-binding cassette domain-containing protein [KO:K01995 K01996 K01998]
E8M01_28785  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_28885  ATP-binding cassette domain-containing protein [KO:K01995 K01996 K01998]
E8M01_33815  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
E8M01_07805  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
E8M01_28435  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
E8M01_13730  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
E8M01_03100  branched-chain amino acid ABC transporter permease [KO:K01995 K01998]
E8M01_03600  branched-chain amino acid ABC transporter permease [KO:K01995 K01998]
E8M01_08065  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_06300  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_08365  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_14190  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_15390  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_14460  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_17915  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_18245  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_02570  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_14795  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_18820  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_19535  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_03220  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_09290  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_21550  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_09605  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_13220  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_11230  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_00540  livM; high-affinity branched-chain amino acid ABC transporter permease LivM [KO:K01998]
E8M01_11465  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_17560  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_01655  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_20020  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_20700  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_01980  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_25740  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_22355  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_22735  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_27540  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_23450  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_23600  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_27895  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_32455  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_28565  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_24810  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_24915  branched-chain amino acid ABC transporter permease [KO:K01998]
E8M01_22375  ABC transporter ATP-binding protein [KO:K01995]
E8M01_13215  ABC transporter ATP-binding protein [KO:K01995]
E8M01_22750  ABC transporter ATP-binding protein [KO:K01995]
E8M01_23605  ABC transporter ATP-binding protein [KO:K01995]
E8M01_27900  ABC transporter ATP-binding protein [KO:K01995]
E8M01_28780  ABC transporter ATP-binding protein [KO:K01995]
E8M01_11235  ABC transporter ATP-binding protein [KO:K01995]
E8M01_00545  ABC transporter ATP-binding protein [KO:K01995]
E8M01_11480  ABC transporter ATP-binding protein [KO:K01995]
E8M01_32460  ABC transporter ATP-binding protein [KO:K01995]
E8M01_08080  ABC transporter ATP-binding protein [KO:K01995]
E8M01_06295  ABC transporter ATP-binding protein [KO:K01995]
E8M01_08375  ABC transporter ATP-binding protein [KO:K01995]
E8M01_14185  ABC transporter ATP-binding protein [KO:K01995]
E8M01_14210  ABC transporter ATP-binding protein [KO:K01995]
E8M01_15395  ABC transporter ATP-binding protein [KO:K01995]
E8M01_17580  ABC transporter ATP-binding protein [KO:K01995]
E8M01_27535  ABC transporter ATP-binding protein [KO:K01995]
E8M01_24815  ABC transporter ATP-binding protein [KO:K01995]
E8M01_14465  ABC transporter ATP-binding protein [KO:K01995]
E8M01_17910  ABC transporter ATP-binding protein [KO:K01995]
E8M01_18250  ABC transporter ATP-binding protein [KO:K01995]
E8M01_01640  ABC transporter ATP-binding protein [KO:K01995]
E8M01_02575  ABC transporter ATP-binding protein [KO:K01995]
E8M01_14790  ABC transporter ATP-binding protein [KO:K01995]
E8M01_20025  ABC transporter ATP-binding protein [KO:K01995]
E8M01_18815  ABC transporter ATP-binding protein [KO:K01995]
E8M01_20695  ABC transporter ATP-binding protein [KO:K01995]
E8M01_20830  ABC transporter ATP-binding protein [KO:K01995]
E8M01_01975  ABC transporter ATP-binding protein [KO:K01995]
E8M01_25745  ABC transporter ATP-binding protein [KO:K01995]
E8M01_28570  ABC transporter ATP-binding protein [KO:K01995]
E8M01_19540  ABC transporter ATP-binding protein [KO:K01995]
E8M01_03095  ABC transporter ATP-binding protein [KO:K01995]
E8M01_03235  ABC transporter ATP-binding protein [KO:K01995]
E8M01_09285  ABC transporter ATP-binding protein [KO:K01995]
E8M01_23455  ABC transporter ATP-binding protein [KO:K01995]
E8M01_24920  ABC transporter ATP-binding protein [KO:K01995]
E8M01_21545  ABC transporter ATP-binding protein [KO:K01995]
E8M01_03605  ATP-binding cassette domain-containing protein [KO:K01995]
E8M01_09595  ABC transporter ATP-binding protein [KO:K01995]
E8M01_08075  ABC transporter ATP-binding protein [KO:K01996]
E8M01_06290  ABC transporter ATP-binding protein [KO:K01996]
E8M01_08355  ABC transporter ATP-binding protein [KO:K01996]
E8M01_14205  ABC transporter ATP-binding protein [KO:K01996]
E8M01_15400  ABC transporter ATP-binding protein [KO:K01996]
E8M01_14470  ABC transporter ATP-binding protein [KO:K01996]
E8M01_17905  ABC transporter ATP-binding protein [KO:K01996]
E8M01_02580  ABC transporter ATP-binding protein [KO:K01996]
E8M01_14785  ABC transporter ATP-binding protein [KO:K01996]
E8M01_18810  ABC transporter ATP-binding protein [KO:K01996]
E8M01_19545  ABC transporter ATP-binding protein [KO:K01996]
E8M01_03090  ABC transporter ATP-binding protein [KO:K01996]
E8M01_03230  ABC transporter ATP-binding protein [KO:K01996]
E8M01_09280  ABC transporter ATP-binding protein [KO:K01996]
E8M01_21540  ABC transporter ATP-binding protein [KO:K01996]
E8M01_09620  ABC transporter ATP-binding protein [KO:K01996]
E8M01_13210  ABC transporter ATP-binding protein [KO:K01996]
E8M01_03610  ABC transporter ATP-binding protein [KO:K01996]
E8M01_13725  ABC transporter ATP-binding protein [KO:K01996]
E8M01_14180  ABC transporter ATP-binding protein [KO:K01996]
E8M01_11240  ABC transporter ATP-binding protein [KO:K01996]
E8M01_00550  ABC transporter ATP-binding protein [KO:K01996]
E8M01_11455  ABC transporter ATP-binding protein [KO:K01996]
E8M01_17575  ABC transporter ATP-binding protein [KO:K01996]
E8M01_01645  ABC transporter ATP-binding protein [KO:K01996]
E8M01_07800  ABC transporter ATP-binding protein [KO:K01996]
E8M01_20030  ABC transporter ATP-binding protein [KO:K01996]
E8M01_20685  ABC transporter ATP-binding protein [KO:K01996]
E8M01_20825  ABC transporter ATP-binding protein [KO:K01996]
E8M01_01970  ABC transporter ATP-binding protein [KO:K01996]
E8M01_33810  ABC transporter ATP-binding protein [KO:K01996]
E8M01_25750  ABC transporter ATP-binding protein [KO:K01996]
E8M01_22370  ABC transporter ATP-binding protein [KO:K01996]
E8M01_22745  ABC transporter ATP-binding protein [KO:K01996]
E8M01_27530  ABC transporter ATP-binding protein [KO:K01996]
E8M01_23460  ABC transporter ATP-binding protein [KO:K01996]
E8M01_23610  ABC transporter ATP-binding protein [KO:K01996]
E8M01_27905  ABC transporter ATP-binding protein [KO:K01996]
E8M01_32465  ABC transporter ATP-binding protein [KO:K01996]
E8M01_28430  ABC transporter ATP-binding protein [KO:K01996]
E8M01_28575  ABC transporter ATP-binding protein [KO:K01996]
E8M01_28775  ATP-binding cassette domain-containing protein [KO:K01996]
E8M01_24820  ABC transporter ATP-binding protein [KO:K01996]
E8M01_24925  ABC transporter ATP-binding protein [KO:K01996]
E8M01_06915  DUF4347 domain-containing protein [KO:K20276]
E8M01_08970  Ig-like domain-containing protein [KO:K20276]
E8M01_13205  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_22725  acyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
E8M01_30675  pimA; dicarboxylate--CoA ligase PimA [KO:K01897] [EC:6.2.1.3]
E8M01_11475  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_08380  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_17535  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_05805  long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_05960  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_01965  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_03295  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_09625  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_06710  acyl--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_21635  acyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
E8M01_29565  AMP-dependent synthetase [KO:K01897] [EC:6.2.1.3]
E8M01_23475  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
E8M01_13355  Crp/Fnr family transcriptional regulator [KO:K10914]
E8M01_23420  Crp/Fnr family transcriptional regulator [KO:K10914]
E8M01_07235  Crp/Fnr family transcriptional regulator [KO:K10914]
E8M01_03425  Crp/Fnr family transcriptional regulator [KO:K10914]
E8M01_09780  transcriptional repressor [KO:K09823]
E8M01_05055  ribA; GTP cyclohydrolase II RibA [KO:K01497] [EC:3.5.4.25]
E8M01_27135  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
E8M01_05050  RibD family protein [KO:K11752] [EC:3.5.4.26 1.1.1.193]
E8M01_28515  DMT family transporter [KO:K09936]
E8M01_07735  efflux transporter outer membrane subunit [KO:K18139]
E8M01_04005  ABC transporter substrate-binding protein [KO:K02035]
E8M01_16085  ABC transporter substrate-binding protein [KO:K02035]
E8M01_22540  ABC transporter substrate-binding protein [KO:K02035]
E8M01_31255  ABC transporter substrate-binding protein [KO:K02035]
E8M01_13130  ABC transporter substrate-binding protein [KO:K02035]
E8M01_28735  ABC transporter substrate-binding protein [KO:K02035]
E8M01_06995  ABC transporter substrate-binding protein [KO:K02035]
E8M01_01145  peptide ABC transporter substrate-binding protein [KO:K02035]
E8M01_11630  ABC transporter substrate-binding protein [KO:K02035]
E8M01_16690  ABC transporter substrate-binding protein [KO:K02035]
E8M01_28170  ABC transporter substrate-binding protein [KO:K02035]
E8M01_08155  ABC transporter substrate-binding protein [KO:K02035]
E8M01_07610  ABC transporter substrate-binding protein [KO:K02035]
E8M01_07630  ABC transporter substrate-binding protein [KO:K02035]
E8M01_25525  ABC transporter substrate-binding protein [KO:K02035]
E8M01_15275  ABC transporter substrate-binding protein [KO:K02035]
E8M01_17610  hypothetical protein [KO:K02035]
E8M01_17645  peptide ABC transporter substrate-binding protein [KO:K02035]
E8M01_17670  ABC transporter substrate-binding protein [KO:K02035]
E8M01_17750  ABC transporter substrate-binding protein [KO:K02035]
E8M01_17755  ABC transporter substrate-binding protein [KO:K02035]
E8M01_27465  peptide ABC transporter substrate-binding protein [KO:K02035]
E8M01_27525  ABC transporter substrate-binding protein [KO:K02035]
E8M01_31695  ABC transporter substrate-binding protein [KO:K02035]
E8M01_08605  ABC transporter substrate-binding protein [KO:K02035]
E8M01_14565  ABC transporter substrate-binding protein [KO:K02035]
E8M01_17985  ABC transporter substrate-binding protein [KO:K02035]
E8M01_11945  twin-arginine translocation signal domain-containing protein [KO:K02035]
E8M01_33430  ABC transporter substrate-binding protein [KO:K02035]
E8M01_14760  ABC transporter substrate-binding protein [KO:K02035]
E8M01_19360  ABC transporter substrate-binding protein [KO:K02035]
E8M01_19805  ABC transporter substrate-binding protein [KO:K02035]
E8M01_18990  ABC transporter substrate-binding protein [KO:K02035]
E8M01_09235  ABC transporter substrate-binding protein [KO:K02035]
E8M01_01855  ABC transporter substrate-binding protein [KO:K02035]
E8M01_05990  ABC transporter substrate-binding protein [KO:K02035]
E8M01_32845  ABC transporter substrate-binding protein [KO:K02035]
E8M01_20255  ABC transporter substrate-binding protein [KO:K02035]
E8M01_20905  ABC transporter substrate-binding protein [KO:K02035]
E8M01_20335  ABC transporter substrate-binding protein [KO:K02035]
E8M01_20570  ABC transporter substrate-binding protein [KO:K02035]
E8M01_03655  ABC transporter substrate-binding protein [KO:K02035]
E8M01_03700  ABC transporter substrate-binding protein [KO:K02035]
E8M01_10020  ABC transporter substrate-binding protein [KO:K02035]
E8M01_18440  ABC transporter substrate-binding protein [KO:K02035]
E8M01_21495  ABC transporter substrate-binding protein [KO:K02035]
E8M01_03470  ABC transporter substrate-binding protein [KO:K02035]
E8M01_14135  ABC transporter substrate-binding protein [KO:K02035]
E8M01_02745  ABC transporter substrate-binding protein [KO:K02035]
E8M01_18785  ABC transporter substrate-binding protein [KO:K02035]
E8M01_09230  ABC transporter permease [KO:K02033]
E8M01_14130  ABC transporter permease [KO:K02033]
E8M01_04000  ABC transporter permease [KO:K02033]
E8M01_22535  ABC transporter permease [KO:K02033]
E8M01_13135  ABC transporter permease [KO:K02033]
E8M01_31395  ABC transporter permease [KO:K02033]
E8M01_01150  ABC transporter permease [KO:K02033]
E8M01_08160  ABC transporter permease [KO:K02033]
E8M01_07680  ABC transporter permease [KO:K02033]
E8M01_15270  ABC transporter permease [KO:K02033]
E8M01_17595  ABC transporter permease [KO:K02033]
E8M01_08600  ABC transporter permease [KO:K02033]
E8M01_17775  ABC transporter permease [KO:K02033]
E8M01_17980  ABC transporter permease [KO:K02033]
E8M01_33425  ABC transporter permease [KO:K02033]
E8M01_02750  ABC transporter permease [KO:K02033]
E8M01_19365  ABC transporter permease [KO:K02033]
E8M01_19810  ABC transporter permease [KO:K02033]
E8M01_20260  ABC transporter permease [KO:K02033]
E8M01_20910  ABC transporter permease [KO:K02033]
E8M01_20575  ABC transporter permease [KO:K02033]
E8M01_10015  ABC transporter permease [KO:K02033]
E8M01_21490  ABC transporter permease [KO:K02033]
E8M01_18775  ABC transporter permease [KO:K02033]
E8M01_17650  ABC transporter permease [KO:K02033]
E8M01_03995  ABC transporter permease [KO:K02034]
E8M01_22530  ABC transporter permease [KO:K02034]
E8M01_13140  ABC transporter permease [KO:K02034]
E8M01_01155  ABC transporter permease [KO:K02034]
E8M01_08165  ABC transporter permease [KO:K02034]
E8M01_07685  ABC transporter permease [KO:K02034]
E8M01_15265  ABC transporter permease [KO:K02034]
E8M01_17590  ABC transporter permease [KO:K02034]
E8M01_17655  ABC transporter permease [KO:K02034]
E8M01_08595  ABC transporter permease [KO:K02034]
E8M01_17770  ABC transporter permease [KO:K02034]
E8M01_17975  ABC transporter permease [KO:K02034]
E8M01_33420  ABC transporter permease [KO:K02034]
E8M01_02755  ABC transporter permease [KO:K02034]
E8M01_19370  ABC transporter permease [KO:K02034]
E8M01_19815  ABC transporter permease [KO:K02034]
E8M01_09225  ABC transporter permease [KO:K02034]
E8M01_20265  ABC transporter permease [KO:K02034]
E8M01_20915  ABC transporter permease [KO:K02034]
E8M01_20580  ABC transporter permease [KO:K02034]
E8M01_10010  ABC transporter permease [KO:K02034]
E8M01_21485  ABC transporter permease [KO:K02034]
E8M01_14125  ABC transporter permease [KO:K02034]
E8M01_18780  ABC transporter permease [KO:K02034]
E8M01_03990  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_22525  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_13145  ABC transporter ATP-binding protein [KO:K02031]
E8M01_31400  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_06945  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_08145  ABC transporter ATP-binding protein [KO:K02031]
E8M01_07690  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_15260  ABC transporter ATP-binding protein [KO:K02031]
E8M01_17605  ABC transporter ATP-binding protein [KO:K02031]
E8M01_08590  ABC transporter ATP-binding protein [KO:K02031]
E8M01_17765  ABC transporter ATP-binding protein [KO:K02031]
E8M01_17970  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_33415  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_02765  ABC transporter ATP-binding protein [KO:K02031]
E8M01_19820  ABC transporter ATP-binding protein [KO:K02031]
E8M01_09220  ABC transporter ATP-binding protein [KO:K02031]
E8M01_20235  ABC transporter ATP-binding protein [KO:K02031]
E8M01_20900  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_20585  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_10005  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_21480  ABC transporter ATP-binding protein [KO:K02031 K02032]
E8M01_14120  ABC transporter ATP-binding protein [KO:K02031]
E8M01_18795  ABC transporter ATP-binding protein [KO:K02031]
E8M01_01160  ABC transporter ATP-binding protein [KO:K02031]
E8M01_17660  ABC transporter ATP-binding protein [KO:K02031]
E8M01_18800  dipeptide ABC transporter ATP-binding protein [KO:K02032]
E8M01_02760  ATP-binding cassette domain-containing protein [KO:K02032]
E8M01_17665  dipeptide ABC transporter ATP-binding protein [KO:K02032]
E8M01_01165  ABC transporter ATP-binding protein [KO:K02032]
E8M01_08150  dipeptide ABC transporter ATP-binding protein [KO:K02032]
E8M01_13150  ATP-binding cassette domain-containing protein [KO:K02032]
E8M01_09215  ATP-binding cassette domain-containing protein [KO:K02032]
E8M01_08585  ATP-binding cassette domain-containing protein [KO:K02032]
E8M01_25500  tagatose 1,6-diphosphate aldolase [KO:K01635] [EC:4.1.2.40]
E8M01_14985  yidC; membrane protein insertase YidC [KO:K03217]
E8M01_33390  secE; preprotein translocase subunit SecE [KO:K03073]
E8M01_32880  secG; preprotein translocase subunit SecG [KO:K03075]
E8M01_33220  secY; preprotein translocase subunit SecY [KO:K03076]
E8M01_33615  yajC; preprotein translocase subunit YajC [KO:K03210]
E8M01_09100  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
E8M01_10570  ftsY; signal recognition particle-docking protein FtsY [KO:K03110]
E8M01_14630  secB; protein-export chaperone SecB [KO:K03071]
E8M01_09355  signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
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Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
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Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
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Norsworthy AN, Visick KL
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Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
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Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
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Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
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Quinolones: from antibiotics to autoinducers.
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FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
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Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
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Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
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Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
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J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
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Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
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Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
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Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
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The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
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PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
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Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
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Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
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Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
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  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
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J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
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  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
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Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
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Planamente S, Morera S, Faure D
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In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
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Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
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  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
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Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
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Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
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Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
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Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
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Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
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Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
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Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
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  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
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Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
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Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
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Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
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Related
pathway
pstg00405  Phenazine biosynthesis
pstg02040  Flagellar assembly
KO pathway
ko02024   
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