KEGG   PATHWAY: ptex00564
Entry
ptex00564                   Pathway                                
Name
Glycerophospholipid metabolism - Pseudonaja textilis (eastern brown snake)
Class
Metabolism; Lipid metabolism
Pathway map
ptex00564  Glycerophospholipid metabolism
ptex00564

Module
ptex_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:ptex00564]
ptex_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:ptex00564]
ptex_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:ptex00564]
Other DBs
GO: 0006650
Organism
Pseudonaja textilis (eastern brown snake) [GN:ptex]
Gene
113441207  glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
113447285  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
113447534  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
113434148  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
113439105  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
113445795  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
113445786  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
113434878  GPAT3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
113447613  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
113449427  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha-like [KO:K13509] [EC:2.3.1.51]
113450092  AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
113448450  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
113444752  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
113439290  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
113432928  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
113433207  LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
113435592  MBOAT1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113432962  MBOAT2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
113439329  GNPAT; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
113437211  ADPRM; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
113440645  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
113435346  PLPP2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
113446854  PLPP1; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
113443286  phospholipid phosphatase 3-like [KO:K01080] [EC:3.1.3.4]
113434418  LPIN3; phosphatidate phosphatase LPIN3 isoform X1 [KO:K15728] [EC:3.1.3.4]
113435499  LPIN2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
113455293  LPIN1; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
113439043  PLPP4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
113447200  PLPP5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
113439483  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
113440055  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
113434811  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
113440938  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
113446802  diacylglycerol kinase delta-like [KO:K00901] [EC:2.7.1.107]
113436738  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
113436775  DGKG; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
113443131  DGKA; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
113443181  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
113444140  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
113454424  CHPT1; cholinephosphotransferase 1 isoform X1 [KO:K00994] [EC:2.7.8.2]
113434510  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
113439766  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
113450327  PLD3; phospholipase D3 isoform X1 [KO:K16860] [EC:3.1.4.4]
113446626  phospholipase D3-like [KO:K16860] [EC:3.1.4.4]
113445308  LCAT; phosphatidylcholine-sterol acyltransferase isoform X1 [KO:K00650] [EC:2.3.1.43]
113444651  PLA2G12B; group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
113450868  PLA2G3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113434790  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113446192  phospholipase A2 homolog otoconin-22-like [KO:K01047] [EC:3.1.1.4]
113441651  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113441652  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113454258  PLA2G1B; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113449729  group IIE secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113449730  basic phospholipase A2 PLA-B-like [KO:K01047] [EC:3.1.1.4]
113449733  basic phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
113438879  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
113439154  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
113451488  PLA2G4C; cytosolic phospholipase A2 gamma [KO:K16342] [EC:3.1.1.4]
113442223  PLA2G4F; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
113442234  cytosolic phospholipase A2 epsilon-like isoform X1 [KO:K16342] [EC:3.1.1.4]
113438047  PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
113438524  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
113438533  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
113438543  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
113438555  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
113438568  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
113438574  cytosolic phospholipase A2 epsilon-like [KO:K16342] [EC:3.1.1.4]
113438593  cytosolic phospholipase A2 beta-like [KO:K16342] [EC:3.1.1.4]
113433195  PLB1; phospholipase B1, membrane-associated [KO:K14621] [EC:3.1.1.4 3.1.1.5]
113446599  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113454623  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113436500  phospholipid-metabolizing enzyme A-C1-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
113445053  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113436550  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
113451187  LPCAT4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
113444542  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
113435426  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
113445112  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
113437566  LYPLA2; acyl-protein thioesterase 2 isoform X1 [KO:K06130] [EC:3.1.1.5]
113446881  PNPLA6; neuropathy target esterase [KO:K14676] [EC:3.1.1.5]
113444044  PNPLA7; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
113442693  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
113445394  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
113454074  ACHE; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
113449611  acetylcholinesterase-like isoform X1 [KO:K01049] [EC:3.1.1.7]
113450641  CHKB; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
113440323  CHKA; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
113442887  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase isoform X1 [KO:K06124] [EC:3.1.3.75]
113450483  PCYT1A; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
113450157  PCYT1B; choline-phosphate cytidylyltransferase B [KO:K00968] [EC:2.7.7.15]
113441628  SELENOI; ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
113446134  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
113442685  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
113437070  PCYT2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
113446675  LOW QUALITY PROTEIN: phosphoethanolamine N-methyltransferase 3-like [KO:K05929] [EC:2.1.1.103]
113434793  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
113438835  PEMT; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
113445836  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
113434877  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
113444446  PLA1A; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
113439889  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
113440334  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
113447041  PISD; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
113437051  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
113442652  CRLS1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
113443331  TAZ; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
113433293  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
113443556  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
113443481  MBOAT7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
113443482  lysophospholipid acyltransferase 7-like [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
ptex00010  Glycolysis / Gluconeogenesis
ptex00260  Glycine, serine and threonine metabolism
ptex00561  Glycerolipid metabolism
ptex00562  Inositol phosphate metabolism
ptex00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
ptex00565  Ether lipid metabolism
ptex00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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