KEGG   PATHWAY: sbia00564
Entry
sbia00564                   Pathway                                
Name
Glycerophospholipid metabolism - Syngnathoides biaculeatus (alligator pipefish)
Class
Metabolism; Lipid metabolism
Pathway map
sbia00564  Glycerophospholipid metabolism
sbia00564

Module
sbia_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:sbia00564]
sbia_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:sbia00564]
sbia_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:sbia00564]
Other DBs
GO: 0006650
Organism
Syngnathoides biaculeatus (alligator pipefish) [GN:sbia]
Gene
133506216  glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
133513126  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
133507412  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like [KO:K00006] [EC:1.1.1.8]
133506072  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
133495722  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
133499176  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
133498867  agpat9l; glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
133499763  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
133490436  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
133510133  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
133512454  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
133509506  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform X1 [KO:K19007] [EC:2.3.1.51]
133513232  lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
133513350  mboat2a; lysophospholipid acyltransferase 2 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
133501349  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
133496488  gnpat; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
133496966  gnpat2; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
133495550  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
133514960  ppap2d; phosphatidic acid phosphatase type 2D isoform X1 [KO:K01080] [EC:3.1.3.4]
133503443  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
133503774  plpp2b; phospholipid phosphatase 2b [KO:K01080] [EC:3.1.3.4]
133491145  plpp1a; LOW QUALITY PROTEIN: phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
133510820  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
133499349  phospholipid phosphatase 1-like [KO:K01080] [EC:3.1.3.4]
133506071  phospholipid phosphatase 3-like isoform X1 [KO:K01080] [EC:3.1.3.4]
133512985  phospholipid phosphatase 2-like [KO:K01080] [EC:3.1.3.4]
133496713  lpin1b; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
133498084  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
133510990  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
133492826  phosphatidate phosphatase LPIN2-like isoform X1 [KO:K15728] [EC:3.1.3.4]
133507281  phosphatidate phosphatase LPIN3-like isoform X1 [KO:K15728] [EC:3.1.3.4]
133509945  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
133499773  plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
133502761  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
133509272  dgkza; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
133504551  diacylglycerol kinase delta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
133510821  dgkaa; diacylglycerol kinase, alpha a isoform X1 [KO:K00901] [EC:2.7.1.107]
133511714  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
133493304  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
133506470  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
133500612  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
133494378  si:dkey-172j4.3; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
133507292  diacylglycerol kinase alpha-like isoform X1 [KO:K00901] [EC:2.7.1.107]
133508294  diacylglycerol kinase theta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
133493561  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
133493563  cholinephosphotransferase 1-like [KO:K00994] [EC:2.7.8.2]
133507151  cept1b; choline/ethanolaminephosphotransferase 1b [KO:K13644] [EC:2.7.8.1 2.7.8.2]
133510014  sphingomyelin synthase-related protein 1-like isoform X1 [KO:K22697] [EC:3.1.4.62]
133495090  samd8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:3.1.4.62]
133509526  sgms1a; phosphatidylcholine:ceramide cholinephosphotransferase 1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
133505753  sgms2a; phosphatidylcholine:ceramide cholinephosphotransferase 2 isoform X1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
133494412  phosphatidylcholine:ceramide cholinephosphotransferase 2-like isoform X1 [KO:K04714] [EC:2.7.8.27 3.1.4.62]
133491981  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
133492883  phospholipase D1-like [KO:K01115] [EC:3.1.4.4]
133513410  pld1a; phospholipase D1a isoform X1 [KO:K01115] [EC:3.1.4.4]
133504448  pld3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
133513714  5'-3' exonuclease PLD4 [KO:K16860] [EC:3.1.4.4]
133508276  pld7; 5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
133502061  lcat; phosphatidylcholine-sterol acyltransferase isoform X1 [KO:K00650] [EC:2.3.1.43]
133509764  pla2g12b; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
133491212  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
133499577  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
133506418  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
133506459  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
133514459  pla2g10; group 10 secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
133503383  pla2g4ab; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
133510263  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
133510264  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
133505781  pla2g6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
133496578  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133496620  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133512919  LOW QUALITY PROTEIN: phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
133509153  rarres3; retinoic acid receptor responder 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
133507276  plaat1l; phospholipase A and acyltransferase 1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
133498149  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
133498924  lpcat1; lysophosphatidylcholine acyltransferase 1 isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
133501099  lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
133494386  lpcat4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
133500715  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
133493067  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
133502062  pla2g15; group XV phospholipase A2 isoform X1 [KO:K06129] [EC:3.1.1.5]
133502875  lypla2; acyl-protein thioesterase 2 isoform X1 [KO:K06130] [EC:3.1.1.5]
133490437  pnpla7a; patatin-like phospholipase domain-containing protein 7a isoform X1 [KO:K14676] [EC:3.1.1.5]
133505987  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
133496533  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
133496006  LOW QUALITY PROTEIN: choline O-acetyltransferase-like [KO:K00623] [EC:2.3.1.6]
133509414  chata; choline O-acetyltransferase isoform X1 [KO:K00623] [EC:2.3.1.6]
133493383  crystal protein [KO:K01049] [EC:3.1.1.7]
133494686  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
133502733  chkb; choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
133501798  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
133495176  probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
133514151  phospho1; probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
133510507  pcyt1aa; choline-phosphate cytidylyltransferase A isoform X1 [KO:K00968] [EC:2.7.7.15]
133491890  choline-phosphate cytidylyltransferase B-like [KO:K00968] [EC:2.7.7.15]
133492567  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
133496718  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
133493456  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
133507652  etnk2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
133501980  ethanolamine kinase 2-like [KO:K00894] [EC:2.7.1.82]
133514999  ethanolamine-phosphate cytidylyltransferase-like isoform X1 [KO:K00967] [EC:2.7.7.14]
133506374  pcyt2; ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
133508398  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
133494637  etnppl; ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
133495574  pemt; phosphatidylethanolamine N-methyltransferase isoform X1 [KO:K00551] [EC:2.1.1.17 2.1.1.71]
133499022  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
133499416  cds2; phosphatidate cytidylyltransferase 2 isoform X1 [KO:K00981] [EC:2.7.7.41]
133511987  pla1a; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
133501149  ptdss1a; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
133501883  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
133490516  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
133495247  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
133509731  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
133504609  tafazzin [KO:K13511] [EC:2.3.1.-]
133496886  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
133514045  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
133501267  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
sbia00010  Glycolysis / Gluconeogenesis
sbia00260  Glycine, serine and threonine metabolism
sbia00561  Glycerolipid metabolism
sbia00562  Inositol phosphate metabolism
sbia00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
sbia00565  Ether lipid metabolism
sbia00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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