KEGG   PATHWAY: sdu04140
Entry
sdu04140                    Pathway                                
Name
Autophagy - animal - Seriola dumerili (greater amberjack)
Description
Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily conserved among eukaryotes and exquisitely regulated. This progress initiates with production of the autophagosome, a double-membrane intracellular structure of reticular origin that engulfs cytoplasmic contents and ultimately fuses with lysosomes for cargo degradation. Autophagy is regulated in response to extra- or intracellular stress and signals such as starvation, growth factor deprivation and ER stress. Constitutive level of autophagy plays an important role in cellular homeostasis and maintains quality control of essential cellular components.
Class
Cellular Processes; Transport and catabolism
Pathway map
sdu04140  Autophagy - animal
sdu04140

Other DBs
GO: 0006914
Organism
Seriola dumerili (greater amberjack) [GN:sdu]
Gene
111221377  ins; insulin [KO:K04526]
111226678  insulin-like [KO:K04526]
111234582  insulin-like [KO:K04526]
111217738  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
111228731  insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
111233019  insulin receptor substrate 1-B-like [KO:K16172]
111218308  irs2; insulin receptor substrate 2 [KO:K07187]
111222710  insulin receptor substrate 2-like [KO:K07187]
111233462  insulin receptor substrate 2-B-like [KO:K07187]
111216431  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
111219094  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
111236831  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
111232818  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
111228886  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
111239022  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
111227486  pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
111236942  phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1 [KO:K02649]
111228846  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
111228984  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
111235342  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
111220410  pdpk1; 3-phosphoinositide-dependent protein kinase 1 [KO:K06276] [EC:2.7.11.1]
111225465  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
111238251  RAC-gamma serine/threonine-protein kinase-like isoform X1 [KO:K04456] [EC:2.7.11.1]
111235389  RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
111234315  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
111233400  RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
111220177  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN-like isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
111235327  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
111228382  hras; GTPase HRas [KO:K02833]
111228455  kras; GTPase KRas isoform X1 [KO:K07827]
111230220  GTPase HRas-like [KO:K07827]
111218153  mras; ras-related protein M-Ras [KO:K07831]
111227963  rras; ras-related protein R-Ras [KO:K07830]
111236562  rras2; ras-related protein R-Ras2 [KO:K07830]
111217320  raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
111228471  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
111232170  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
111229041  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
111236845  mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
111230214  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
111220260  epas1; endothelial PAS domain-containing protein 1 [KO:K08268]
111225342  hif1a; LOW QUALITY PROTEIN: hypoxia-inducible factor 1-alpha [KO:K08268]
111216921  hypoxia-inducible factor 3-alpha-like [KO:K08268]
111220111  ddit4; DNA damage-inducible transcript 4 protein [KO:K08270]
111235348  DNA damage-inducible transcript 4 protein-like [KO:K08270]
111229195  tsc2; tuberin isoform X1 [KO:K07207]
111236140  hamartin-like [KO:K07206]
111238487  hamartin-like isoform X1 [KO:K07206]
111239883  BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like [KO:K15464]
111235195  bnip3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 [KO:K15464]
111221638  GTP-binding protein Rheb-like [KO:K07208]
111237415  GTP-binding protein Rheb-like isoform X1 [KO:K07208]
111231088  GTP-binding protein Rheb [KO:K07208]
111217934  rptor; regulatory-associated protein of mTOR [KO:K07204]
111221882  DEP domain-containing mTOR-interacting protein-like [KO:K20402]
111227677  deptor; DEP domain-containing mTOR-interacting protein isoform X1 [KO:K20402]
111227586  mtor; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
111217583  akt1s1; proline-rich AKT1 substrate 1 [KO:K16184]
111222200  ribosomal protein S6 kinase beta-1-like isoform X1 [KO:K04688] [EC:2.7.11.1]
111217916  ribosomal protein S6 kinase beta-2-like [KO:K04688] [EC:2.7.11.1]
111239086  ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
111230376  igbp1; immunoglobulin-binding protein 1 [KO:K17606]
111226526  serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like isoform X1 [KO:K04382] [EC:3.1.3.16]
111236941  ppp2cb; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
111234362  ppp2ca; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
111231860  serine/threonine-protein kinase ULK1-like isoform X1 [KO:K21357] [EC:2.7.11.1]
111233068  ulk1; serine/threonine-protein kinase ULK1 isoform X1 [KO:K21357] [EC:2.7.11.1]
111226280  ulk2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
111239927  atg13; autophagy-related protein 13 isoform X1 [KO:K08331]
111222378  atg101; autophagy-related protein 101 [KO:K19730]
111231008  rb1cc1; RB1-inducible coiled-coil protein 1 isoform X1 [KO:K17589]
111232476  atg2a; autophagy-related protein 2 homolog A isoform X1 [KO:K17906]
111225644  atg2b; autophagy-related protein 2 homolog B isoform X1 [KO:K17906]
111219550  wipi1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 [KO:K17908]
111236271  WD repeat domain phosphoinositide-interacting protein 1-like isoform X1 [KO:K17908]
111230321  wipi2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908]
111220408  wdr45b; WD repeat domain phosphoinositide-interacting protein 3 [KO:K22991]
111224270  wdr45; WD repeat domain phosphoinositide-interacting protein 4 [KO:K22991]
111230994  autophagy-related protein 9A-like [KO:K17907]
111225869  atg9a; autophagy-related protein 9A [KO:K17907]
111217176  supt20h; transcription factor SPT20 homolog isoform X1 [KO:K21245]
111216673  guanine nucleotide exchange protein smcr8a-like isoform X1 [KO:K23611]
111230342  smcr8; guanine nucleotide exchange protein SMCR8 [KO:K23611]
111239036  wdr41; WD repeat-containing protein 41 [KO:K23610]
111226191  cunh9orf72; guanine nucleotide exchange C9orf72 homolog [KO:K23609]
111231003  ras-related protein Rab-8A-like [KO:K07901]
111232134  rab8a; ras-related protein Rab-8A [KO:K07901]
111217083  ras-related protein Rab-39B-like [KO:K07925]
111233454  rab39b; ras-related protein Rab-39B [KO:K07925]
111233501  sqstm1; sequestosome-1 isoform X1 [KO:K14381]
111229518  tbk1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
111218840  tank; TRAF family member-associated NF-kappa-B activator [KO:K12650]
111216970  ras-related protein Rab-1B-like [KO:K07874]
111220607  ras-related protein ORAB-1-like [KO:K07874]
111237576  ras-related protein Rab-1A [KO:K07874]
111234619  ras-related GTP-binding protein A [KO:K16185]
111223137  ras-related GTP-binding protein C-like [KO:K16186]
111235821  rragc; ras-related GTP-binding protein C [KO:K16186]
111226203  ras-related GTP-binding protein D-like isoform X1 [KO:K16186]
111228977  stk11; serine/threonine-protein kinase STK11 [KO:K07298] [EC:2.7.11.1]
111237369  prkaa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1 [KO:K07198] [EC:2.7.11.31]
111226317  prkaa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1 [KO:K07198] [EC:2.7.11.31]
111220870  prkacb; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
111229212  prkaca; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
111227008  cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
111221681  prkcd; protein kinase C delta type [KO:K06068] [EC:2.7.11.13]
111221709  protein kinase C delta type-like [KO:K06068] [EC:2.7.11.13]
111219534  mitogen-activated protein kinase 8-like [KO:K04440] [EC:2.7.11.24]
111226417  mitogen-activated protein kinase 9-like [KO:K04440] [EC:2.7.11.24]
111234720  mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
111235092  mitogen-activated protein kinase 8-like isoform X1 [KO:K04440] [EC:2.7.11.24]
111236887  apoptosis regulator Bcl-2-like isoform X1 [KO:K02161]
111239004  bcl2; apoptosis regulator Bcl-2 [KO:K02161]
111221542  bcl-2-like protein 1 [KO:K04570]
111234723  bcl2l1; bcl-2-like protein 1 [KO:K04570]
111231315  bad; bcl2-associated agonist of cell death [KO:K02158]
111219708  becn1; beclin-1 [KO:K08334]
111237095  nrbf2; nuclear receptor-binding factor 2 [KO:K21246]
111233666  pik3r4; phosphoinositide 3-kinase regulatory subunit 4 isoform X1 [KO:K08333] [EC:2.7.11.1]
111235652  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
111237164  atg14; beclin 1-associated autophagy-related key regulator [KO:K17889]
111233714  ambra1; activating molecule in BECN1-regulated autophagy protein 1 isoform X1 [KO:K17985]
111223588  traf6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
111219313  tp53inp2; tumor protein p53-inducible nuclear protein 2 isoform X1 [KO:K21247]
111220405  tumor protein p53-inducible nuclear protein 2-like [KO:K21247]
111222250  vmp1; vacuole membrane protein 1 isoform X1 [KO:K21248]
111239111  vacuole membrane protein 1-like [KO:K21248]
111236920  stx17; syntaxin-17 [KO:K08491]
111222367  uvrag; UV radiation resistance-associated gene protein [KO:K21249]
111228252  sh3glb1; endophilin-B1 isoform X1 [KO:K11248]
111216331  rubcn; run domain Beclin-1-interacting and cysteine-rich domain-containing protein isoform X1 [KO:K19330]
111238941  calcium/calmodulin-dependent protein kinase kinase 2-like isoform X1 [KO:K07359] [EC:2.7.11.17]
111238781  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
111226008  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
111216736  serine/threonine-protein kinase/endoribonuclease IRE1-like isoform X1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
111227244  ern1; serine/threonine-protein kinase/endoribonuclease IRE1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
111221456  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
111221798  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
111230605  death-associated protein kinase 2-like [KO:K08803] [EC:2.7.11.1]
111224364  death-associated protein kinase 3-like [KO:K08803] [EC:2.7.11.1]
111227986  dapk1; death-associated protein kinase 1 [KO:K08803] [EC:2.7.11.1]
111228368  dapk2; death-associated protein kinase 2 isoform X1 [KO:K08803] [EC:2.7.11.1]
111231263  dapk3; death-associated protein kinase 3 [KO:K08803] [EC:2.7.11.1]
111217084  hmgb1; high mobility group protein B1 [KO:K10802]
111224459  high mobility group protein B1-like [KO:K10802]
111226127  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
111225274  eif2ak4; eIF-2-alpha kinase GCN2 [KO:K16196] [EC:2.7.11.1]
111235659  eif2s1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
111222182  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
111231006  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
111221688  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
111237627  zinc finger FYVE domain-containing protein 1-like [KO:K17603]
111225703  zinc finger FYVE domain-containing protein 1-like [KO:K17603]
111232820  zinc finger FYVE domain-containing protein 1-like [KO:K17603]
111230134  atg12; ubiquitin-like protein ATG12 [KO:K08336]
111222457  atg5; autophagy protein 5 isoform X1 [KO:K08339]
111216835  atg16l1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
111216925  autophagy-related protein 16-2-like isoform X1 [KO:K20868]
111224015  atg7; ubiquitin-like modifier-activating enzyme ATG7 [KO:K08337]
111233301  atg10; ubiquitin-like-conjugating enzyme ATG10 [KO:K17888]
111232227  atg3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
111218114  cflar; CASP8 and FADD-like apoptosis regulator [KO:K04724]
111218350  ras-related protein Rab-33B-like isoform X1 [KO:K07920]
111229372  ras-related protein Rab-33B-like [KO:K07920]
111230383  rab33b; ras-related protein Rab-33B [KO:K07920]
111224634  prkcq; protein kinase C theta type isoform X1 [KO:K18052] [EC:2.7.11.13]
111224855  gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
111238835  gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
111233024  gabarap; gamma-aminobutyric acid receptor-associated protein [KO:K08341]
111230109  gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
111225231  microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
111219463  map1lc3a; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
111232964  map1lc3c; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
111232381  microtubule-associated proteins 1A/1B light chain 3C-like [KO:K10435]
111217299  atg4c; cysteine protease ATG4C [KO:K08342] [EC:3.4.22.-]
111231550  cysteine protease ATG4D-like [KO:K08342] [EC:3.4.22.-]
111238063  cysteine protease ATG4D-like [KO:K08342] [EC:3.4.22.-]
111231992  atg4b; cysteine protease ATG4B isoform X1 [KO:K08342] [EC:3.4.22.-]
111219998  next to BRCA1 gene 1 protein-like isoform X1 [KO:K17987]
111236255  next to BRCA1 gene 1 protein-like isoform X1 [KO:K17987]
111225058  optn; optineurin [KO:K19946]
111219974  calcoco2; calcium-binding and coiled-coil domain-containing protein 2 isoform X1 [KO:K21348]
111223177  tax1-binding protein 1 homolog B-like isoform X1 [KO:K21347]
111238800  tax1-binding protein 1 homolog B-like isoform X1 [KO:K21347]
111227988  wdfy3; WD repeat and FYVE domain-containing protein 3 [KO:K22262]
111217001  uba52; ubiquitin-60S ribosomal protein L40 [KO:K02927]
111228782  ubiquitin-60S ribosomal protein L40-like [KO:K02927]
111224188  rps27a; ubiquitin-40S ribosomal protein S27a isoform X1 [KO:K02977]
111222381  ubc; polyubiquitin-C [KO:K08770]
111236493  snap29; synaptosomal-associated protein 29 [KO:K08509]
111239031  vesicle-associated membrane protein 8-like isoform X1 [KO:K08512]
111228410  vesicle-associated membrane protein 8-like [KO:K08512]
111228418  vesicle-associated membrane protein 8-like [KO:K08512]
111236545  ykt6; synaptobrevin homolog YKT6 [KO:K08516]
111239640  stx7; syntaxin-7 [KO:K08488]
111226711  epg5; ectopic P granules protein 5 homolog [KO:K23883]
111220282  plekhm1; pleckstrin homology domain-containing family M member 1 isoform X1 [KO:K23282]
111222366  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
111235574  vps16; vacuolar protein sorting-associated protein 16 homolog [KO:K20180]
111216444  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
111228751  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
111226074  vps39; vam6/Vps39-like protein isoform X1 [KO:K20183]
111237842  vps41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
111236425  birc6; baculoviral IAP repeat-containing protein 6 isoform X1 [KO:K10586] [EC:2.3.2.23]
111220995  Golgi reassembly-stacking protein 1-like [KO:K26797]
111228803  Golgi reassembly-stacking protein 1-like [KO:K26797]
111218856  gorasp2; Golgi reassembly-stacking protein 2 [KO:K26797]
111229174  Golgi reassembly-stacking protein 2-like [KO:K26797]
111221645  ras-related protein rab7-like [KO:K07897]
111221504  ras-related protein rab7-like [KO:K07897]
111221715  ras-related protein rab7 isoform X1 [KO:K07897]
111218880  lysosome-associated membrane glycoprotein 1-like [KO:K06528]
111232692  lamp2; lysosome-associated membrane glycoprotein 2 isoform X1 [KO:K06528]
111238358  lamp1; lysosome-associated membrane glycoprotein 1 [KO:K06528]
111223324  ctsd; cathepsin D [KO:K01379] [EC:3.4.23.5]
111230367  cathepsin D-like [KO:K01379] [EC:3.4.23.5]
111227987  ctsl; cathepsin L1 [KO:K01365] [EC:3.4.22.15]
111225856  uncharacterized protein LOC111225856 [KO:K01365] [EC:3.4.22.15]
111226333  cathepsin L1-like [KO:K01365] [EC:3.4.22.15]
111219327  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
111239355  cathepsin B-like [KO:K01363] [EC:3.4.22.1]
Compound
C00035  GDP
C00044  GTP
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:15325584
  Authors
Meijer AJ, Codogno P.
  Title
Regulation and role of autophagy in mammalian cells.
  Journal
Int J Biochem Cell Biol 36:2445-62 (2004)
DOI:10.1016/j.biocel.2004.02.002
Reference
PMID:16099218
  Authors
Deretic V.
  Title
Autophagy in innate and adaptive immunity.
  Journal
Trends Immunol 26:523-8 (2005)
DOI:10.1016/j.it.2005.08.003
Reference
PMID:16200202
  Authors
Levine B, Yuan J.
  Title
Autophagy in cell death: an innocent convict?
  Journal
J Clin Invest 115:2679-88 (2005)
DOI:10.1172/JCI26390
Reference
PMID:15325588
  Authors
Tanida I, Ueno T, Kominami E.
  Title
LC3 conjugation system in mammalian autophagy.
  Journal
Int J Biochem Cell Biol 36:2503-18 (2004)
DOI:10.1016/j.biocel.2004.05.009
Reference
PMID:15928708
  Authors
Lum JJ, DeBerardinis RJ, Thompson CB.
  Title
Autophagy in metazoans: cell survival in the land of plenty.
  Journal
Nat Rev Mol Cell Biol 6:439-48 (2005)
DOI:10.1038/nrm1660
Reference
PMID:15978794
  Authors
Reggiori F, Klionsky DJ.
  Title
Autophagosomes: biogenesis from scratch?
  Journal
Curr Opin Cell Biol 17:415-22 (2005)
DOI:10.1016/j.ceb.2005.06.007
Reference
PMID:11099404
  Authors
Klionsky DJ, Emr SD.
  Title
Autophagy as a regulated pathway of cellular degradation.
  Journal
Science 290:1717-21 (2000)
DOI:10.1126/science.290.5497.1717
Reference
PMID:16125113
  Authors
Bechet D, Tassa A, Taillandier D, Combaret L, Attaix D.
  Title
Lysosomal proteolysis in skeletal muscle.
  Journal
Int J Biochem Cell Biol 37:2098-114 (2005)
DOI:10.1016/j.biocel.2005.02.029
Reference
PMID:19653858
  Authors
He C, Klionsky DJ
  Title
Regulation mechanisms and signaling pathways of autophagy.
  Journal
Annu Rev Genet 43:67-93 (2009)
DOI:10.1146/annurev-genet-102808-114910
Reference
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Curr Opin Cell Biol 22:124-31 (2010)
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PMID:21187343
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Chen Y, Klionsky DJ
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J Cell Sci 124:161-70 (2011)
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The role of Atg proteins in autophagosome formation.
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Annu Rev Cell Dev Biol 27:107-32 (2011)
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Cell Res 24:42-57 (2014)
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Related
pathway
sdu04010  MAPK signaling pathway
sdu04141  Protein processing in endoplasmic reticulum
sdu04142  Lysosome
sdu04150  mTOR signaling pathway
sdu04910  Insulin signaling pathway
KO pathway
ko04140   
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