KEGG   PATHWAY: slx02024
Entry
slx02024                    Pathway                                
Name
Quorum sensing - Streptomyces lavendulae subsp. lavendulae
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
slx02024  Quorum sensing
slx02024

Other DBs
GO: 0009372
Organism
Streptomyces lavendulae subsp. lavendulae [GN:slx]
Gene
SLAV_27035  trpE; Anthranilate synthase component 1 [KO:K01657] [EC:4.1.3.27]
SLAV_26620  aroH; Phospho-2-dehydro-3-deoxyheptonate aldolase [KO:K01626] [EC:2.5.1.54]
SLAV_26615  phnA; Anthranilate synthase component 1, pyocyanine specific [KO:K13063] [EC:2.6.1.86]
SLAV_03550  phzF; Trans-2,3-dihydro-3-hydroxyanthranilate isomerase [KO:K06998] [EC:5.3.3.17]
SLAV_05520  kdpE1; KDP operon transcriptional regulatory protein KdpE [KO:K07667]
SLAV_10510  kdpE2; KDP operon transcriptional regulatory protein KdpE [KO:K07667]
SLAV_04425  gadB; Glutamate decarboxylase beta [KO:K01580] [EC:4.1.1.15]
SLAV_06635  Bacterial extracellular solute-binding protein [KO:K02055]
SLAV_33400  hypothetical protein [KO:K02055]
SLAV_33410  thiamine transporter membrane protein [KO:K02053]
SLAV_33405  spermidine/putrescine ABC transporter membrane protein [KO:K02054]
SLAV_33415  cysA3; Sulfate/thiosulfate import ATP-binding protein CysA [KO:K02052]
SLAV_27575  braC; Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor [KO:K01999]
SLAV_07820  hypothetical protein [KO:K01999]
SLAV_17015  hypothetical protein [KO:K01999]
SLAV_27570  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
SLAV_27565  leucine/isoleucine/valine transporter permease subunit [KO:K01998]
SLAV_07830  lptB1; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995]
SLAV_27560  lptB2; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995]
SLAV_27555  livF2; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
SLAV_17590  Transglutaminase-activating metalloprotease precursor [KO:K20273]
SLAV_07815  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
SLAV_21845  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
SLAV_21870  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
SLAV_32915  Long-chain-fatty-acid--CoA ligase FadD13 [KO:K01897] [EC:6.2.1.3]
SLAV_26545  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
SLAV_24750  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
SLAV_29000  lcfB4; Long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
SLAV_08185  lcfB2; Long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
SLAV_39935  Long-chain-fatty-acid--CoA ligase FadD15 [KO:K01897] [EC:6.2.1.3]
SLAV_19470  hypothetical protein [KO:K10914]
SLAV_20635  crp3; cAMP receptor protein [KO:K10914]
SLAV_07250  crp1; cAMP receptor protein [KO:K10914]
SLAV_15975  crp2; cAMP receptor protein [KO:K10914]
SLAV_32705  hypothetical protein [KO:K20331] [EC:2.1.1.349]
SLAV_30490  ribD2; Riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
SLAV_14030  oppA2; Oligopeptide-binding protein OppA precursor [KO:K15580]
SLAV_14060  oppA3; Oligopeptide-binding protein OppA precursor [KO:K15580]
SLAV_14025  dppB3; Dipeptide transport system permease protein DppB [KO:K15581]
SLAV_14055  gsiC3; Glutathione transport system permease protein GsiC [KO:K15581]
SLAV_14020  gsiD4; Glutathione transport system permease protein GsiD [KO:K15582]
SLAV_14050  oppC2; Oligopeptide transport system permease protein OppC [KO:K15582]
SLAV_14015  oppD4; Oligopeptide transport ATP-binding protein OppD [KO:K15583]
SLAV_14045  oppD5; Oligopeptide transport ATP-binding protein OppD [KO:K15583]
SLAV_14010  oppF4; Oligopeptide transport ATP-binding protein OppF [KO:K10823]
SLAV_14040  oppF5; Oligopeptide transport ATP-binding protein OppF [KO:K10823]
SLAV_03820  gsiB1; Glutathione-binding protein GsiB precursor [KO:K02035]
SLAV_10105  oppA1; Periplasmic oligopeptide-binding protein precursor [KO:K02035]
SLAV_31390  appA1; Oligopeptide-binding protein AppA precursor [KO:K02035]
SLAV_31465  appA2; Oligopeptide-binding protein AppA precursor [KO:K02035]
SLAV_31775  dppA2; Periplasmic dipeptide transport protein precursor [KO:K02035]
SLAV_15255  hbpA2; Heme-binding protein A precursor [KO:K02035]
SLAV_13765  gsiB2; Glutathione-binding protein GsiB precursor [KO:K02035]
SLAV_14070  putative monoacyl phosphatidylinositol tetramannoside-binding protein LpqW precursor [KO:K02035]
SLAV_30975  ddpA2; putative D,D-dipeptide-binding periplasmic protein DdpA precursor [KO:K02035]
SLAV_29230  dppE; Dipeptide-binding protein DppE precursor [KO:K02035]
SLAV_29235  ddpA1; putative D,D-dipeptide-binding periplasmic protein DdpA precursor [KO:K02035]
SLAV_12375  hbpA1; Heme-binding protein A precursor [KO:K02035]
SLAV_03815  gsiC1; Glutathione transport system permease protein GsiC [KO:K02033]
SLAV_10095  dppB1; Dipeptide transport system permease protein DppB [KO:K02033]
SLAV_31395  dppB4; Dipeptide transport system permease protein DppB [KO:K02033]
SLAV_31470  gsiC4; Glutathione transport system permease protein GsiC [KO:K02033]
SLAV_31780  oppB; Oligopeptide transport system permease protein OppB [KO:K02033]
SLAV_13755  dppB2; Dipeptide transport system permease protein DppB [KO:K02033]
SLAV_12370  gsiC2; Glutathione transport system permease protein GsiC [KO:K02033]
SLAV_03810  gsiD1; Glutathione transport system permease protein GsiD [KO:K02034]
SLAV_31400  oppC3; Oligopeptide transport system permease protein OppC [KO:K02034]
SLAV_31475  gsiD5; Glutathione transport system permease protein GsiD [KO:K02034]
SLAV_31785  gsiD6; Glutathione transport system permease protein GsiD [KO:K02034]
SLAV_13760  gsiD3; Glutathione transport system permease protein GsiD [KO:K02034]
SLAV_12380  gsiD2; Glutathione transport system permease protein GsiD [KO:K02034]
SLAV_10100  oppC1; Oligopeptide transport system permease protein OppC [KO:K02034]
SLAV_03805  oppD1; Oligopeptide transport ATP-binding protein OppD [KO:K02031]
SLAV_10090  oppD2; Oligopeptide transport ATP-binding protein OppD [KO:K02031]
SLAV_31405  oppD6; Oligopeptide transport ATP-binding protein OppD [KO:K02031]
SLAV_31480  gsiA2; Glutathione import ATP-binding protein GsiA [KO:K02031 K02032]
SLAV_31790  oppD7; Oligopeptide transport ATP-binding protein OppD [KO:K02031]
SLAV_13750  gsiA1; Glutathione import ATP-binding protein GsiA [KO:K02031 K02032]
SLAV_12365  oppD3; Oligopeptide transport ATP-binding protein OppD [KO:K02031]
SLAV_12360  oppF3; Oligopeptide transport ATP-binding protein OppF [KO:K02032]
SLAV_31795  oppF7; Oligopeptide transport ATP-binding protein OppF [KO:K02032]
SLAV_31410  oppF6; Oligopeptide transport ATP-binding protein OppF [KO:K02032]
SLAV_10085  oppF2; Oligopeptide transport ATP-binding protein OppF [KO:K02032]
SLAV_19210  yidC; Membrane protein insertase YidC [KO:K03217]
SLAV_23620  membrane protein insertase [KO:K03217]
SLAV_33530  bprV; Extracellular basic protease precursor [KO:K14645] [EC:3.4.21.-]
SLAV_16045  preprotein translocase subunit SecE [KO:K03073]
SLAV_27855  preprotein translocase subunit SecG [KO:K03075]
SLAV_15835  preprotein translocase subunit SecY [KO:K03076]
SLAV_29915  preprotein translocase subunit YajC [KO:K03210]
SLAV_23035  preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
SLAV_11775  ftsY; Signal recognition particle receptor FtsY [KO:K03110]
SLAV_11745  ffh; Signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
SLAV_09770  plcN1; Non-hemolytic phospholipase C precursor [KO:K01114] [EC:3.1.4.3]
SLAV_12120  plcN2; Non-hemolytic phospholipase C precursor [KO:K01114] [EC:3.1.4.3]
SLAV_33870  plcN3; Non-hemolytic phospholipase C precursor [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
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Infect Immun 83:2430-42 (2015)
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J Bacteriol 191:3919-27 (2009)
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Quorum sensing and bacterial social interactions in biofilms.
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Sensors (Basel) 12:2519-38 (2012)
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Appl Environ Microbiol 78:3515-22 (2012)
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Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
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Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
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Peptides 25:1405-14 (2004)
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Bacterial quorum sensing: its role in virulence and possibilities for its control.
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Exploiting quorum sensing to confuse bacterial pathogens.
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Microbiol Mol Biol Rev 77:73-111 (2013)
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Healthcare epidemiology: quorum sensing: bacteria talk sense.
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Clin Infect Dis 47:1070-6 (2008)
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Related
pathway
slx00405  Phenazine biosynthesis
slx02040  Flagellar assembly
KO pathway
ko02024   
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