KEGG   PATHWAY: sly00230
Entry
sly00230                    Pathway                                
Name
Purine metabolism - Solanum lycopersicum (tomato)
Class
Metabolism; Nucleotide metabolism
Pathway map
sly00230  Purine metabolism
sly00230

Module
sly_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sly00230]
sly_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sly00230]
sly_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sly00230]
sly_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sly00230]
sly_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sly00230]
Other DBs
GO: 0006163 0042278
Organism
Solanum lycopersicum (tomato) [GN:sly]
Gene
101246124  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
101259154  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
101245949  nudix hydrolase 2 isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
101263765  nudix hydrolase 2 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
101263980  nudix hydrolase 23, chloroplastic isoform X6 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
101256314  nudix hydrolase 14, chloroplastic [KO:K18447] [EC:3.6.1.21]
101267287  phosphoglucomutase, chloroplastic [KO:K01835] [EC:5.4.2.2]
101267885  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
101263060  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
101244195  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
101262942  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
101250934  amidophosphoribosyltransferase, chloroplastic [KO:K00764] [EC:2.4.2.14]
101266758  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
101265372  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
101252648  phosphoribosylglycinamide formyltransferase, chloroplastic [KO:K00601] [EC:2.1.2.2]
101268249  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
101246417  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial [KO:K01933] [EC:6.3.3.1]
101255944  phosphoribosylaminoimidazole carboxylase, chloroplastic-like [KO:K11808] [EC:4.1.1.21]
101262799  phosphoribosylaminoimidazole carboxylase, chloroplastic-like [KO:K11808] [EC:4.1.1.21]
101258302  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
101263129  uncharacterized protein LOC101263129 [KO:K01756] [EC:4.3.2.2]
100316897  IMPCHase; putative inosine monophosphate cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
101260722  adenine phosphoribosyltransferase 1 [KO:K00759] [EC:2.4.2.7]
101248507  adenine phosphoribosyltransferase 4 [KO:K00759] [EC:2.4.2.7]
101263094  uncharacterized protein LOC101263094 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
101253828  uncharacterized protein LOC101253828 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
101267031  uncharacterized protein LOC101267031 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
101261528  uncharacterized protein LOC101261528 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
101261826  uncharacterized protein LOC101261826 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
101262298  uncharacterized protein LOC101262298 [KO:K00760] [EC:2.4.2.8]
101266279  inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
101244761  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
544095  NDK; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
101262221  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
104648939  nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
101260252  nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
101268182  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
101252471  probable apyrase 2 [KO:K14641] [EC:3.6.1.5]
101250072  apyrase isoform X1 [KO:K14641] [EC:3.6.1.5]
101249402  apyrase-like [KO:K14641] [EC:3.6.1.5]
109119465  apyrase-like [KO:K14641] [EC:3.6.1.5]
101258050  apyrase [KO:K14641] [EC:3.6.1.5]
101262543  apyrase 2 [KO:K14641] [EC:3.6.1.5]
101254338  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
101252744  xanthine dehydrogenase 1-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
101252457  xanthine dehydrogenase 1-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
101250796  nudix hydrolase 25 [KO:K26955] [EC:3.6.1.17]
101256508  uncharacterized protein LOC101256508 [KO:K01951] [EC:6.3.5.2]
101248066  guanylate kinase 2, chloroplastic/mitochondrial [KO:K00942] [EC:2.7.4.8]
101261672  guanylate kinase 2-like [KO:K00942] [EC:2.7.4.8]
101246321  guanylate kinase [KO:K00942] [EC:2.7.4.8]
101249065  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
101263997  ribonucleoside-diphosphate reductase large subunit isoform X1 [KO:K10807] [EC:1.17.4.1]
101261156  ribonucleoside-diphosphate reductase small chain A-like [KO:K10808] [EC:1.17.4.1]
101268630  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
101246425  HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
101257084  HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
112940880  uncharacterized protein LOC112940880 [KO:K01514] [EC:3.6.1.11]
101250287  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
101253322  putative GTP diphosphokinase RSH1, chloroplastic isoform X4 [KO:K00951] [EC:2.7.6.5]
101251456  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
101266068  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
101253148  adenylosuccinate synthetase, chloroplastic [KO:K01939] [EC:6.3.4.4]
101258802  adenylosuccinate synthetase, chloroplastic [KO:K01939] [EC:6.3.4.4]
101246464  adenosine monophosphate deaminase [KO:K01490] [EC:3.5.4.6]
101254382  probable AMP deaminase [KO:K01490] [EC:3.5.4.6]
101251530  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
101244800  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
101251751  nucleoside/nucleotide kinase superfamily protein [KO:K00939] [EC:2.7.4.3]
101246297  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
101265630  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
101261649  adenylate kinase [KO:K00939] [EC:2.7.4.3]
101254478  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
101248270  adenylate kinase 5, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
101253795  adenylate kinase, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
101264422  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
101055607  Hop-interacting protein THI105 [KO:K18532] [EC:2.7.4.3]
101260825  adenylate kinase isoenzyme 6 homolog isoform X2 [KO:K18532] [EC:2.7.4.3]
101263792  uncharacterized protein LOC101263792 [KO:K06928] [EC:3.6.1.15]
101247040  ectonucleotide pyrophosphatase/phosphodiesterase family member 3-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
101251711  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
101256557  ATP sulfurylase 1, chloroplastic [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101259979  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101256255  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
101247286  adenylyl-sulfate kinase 3 [KO:K00860] [EC:2.7.1.25]
101267663  adenylyl-sulfate kinase 3 [KO:K00860] [EC:2.7.1.25]
101262973  adenylyl-sulfate kinase 3 [KO:K00860] [EC:2.7.1.25]
100037732  urate oxidase [KO:K00365] [EC:1.7.3.3]
101253420  uric acid degradation bifunctional protein TTL isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
101245519  allantoinase [KO:K01466] [EC:3.5.2.5]
101266592  allantoate deiminase 2 [KO:K02083] [EC:3.5.3.9]
101248901  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
101246378  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
101264119  urease isoform X1 [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sly00030  Pentose phosphate pathway
sly00220  Arginine biosynthesis
sly00250  Alanine, aspartate and glutamate metabolism
sly00260  Glycine, serine and threonine metabolism
sly00340  Histidine metabolism
sly00630  Glyoxylate and dicarboxylate metabolism
sly00730  Thiamine metabolism
sly00740  Riboflavin metabolism
sly00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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