KEGG   PATHWAY: strr00630
Entry
strr00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomonospora litoralis
Class
Metabolism; Carbohydrate metabolism
Pathway map
strr00630  Glyoxylate and dicarboxylate metabolism
strr00630

Module
strr_M00012  Glyoxylate cycle [PATH:strr00630]
strr_M00621  Glycine cleavage system [PATH:strr00630]
strr_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:strr00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomonospora litoralis [GN:strr]
Gene
EKD16_11645  icl; Isocitrate lyase [KO:K01637] [EC:4.1.3.1]
EKD16_12370  acsA3; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
EKD16_00840  acsA1; Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
EKD16_07475  aceB; Malate synthase [KO:K01638] [EC:2.3.3.9]
EKD16_08000  mdh; Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
EKD16_23190  gltA2; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
EKD16_15895  gltA1; Citrate synthase [KO:K01647] [EC:2.3.3.1]
EKD16_02360  citA; Citrate synthase 1 [KO:K01647] [EC:2.3.3.1]
EKD16_14725  acnA; Aconitate hydratase [KO:K01681] [EC:4.2.1.3]
EKD16_15920  dmdA; 2,3-dimethylmalate dehydratase large subunit [KO:K01681] [EC:4.2.1.3]
EKD16_02390  paaJ1; 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
EKD16_20150  fadA; 3-ketoacyl-CoA thiolase [KO:K00626] [EC:2.3.1.9]
EKD16_05355  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
EKD16_05350  Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily protein [KO:K05606] [EC:5.1.99.1]
EKD16_03145  cfiB; 2-oxoglutarate carboxylase small subunit [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
EKD16_03155  accD1; putative propionyl-CoA carboxylase beta chain 5 [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
EKD16_03150  hypothetical protein [KO:K27095]
EKD16_01465  mutA; Methylmalonyl-CoA mutase small subunit [KO:K01847] [EC:5.4.99.2]
EKD16_01475  mutB; Methylmalonyl-CoA mutase large subunit [KO:K01847] [EC:5.4.99.2]
EKD16_07470  putative FAD-linked oxidoreductase [KO:K00104] [EC:1.1.99.14]
EKD16_07465  putative FAD-linked oxidoreductase [KO:K11472] [EC:1.1.99.14]
EKD16_07460  lutA1; Lactate utilization protein A [KO:K11473] [EC:1.1.99.14]
EKD16_13070  katE; Catalase HPII [KO:K03781] [EC:1.11.1.6]
EKD16_00975  katA; Catalase [KO:K03781] [EC:1.11.1.6]
EKD16_21820  gph3; Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
EKD16_09790  glnA1; putative glutamine synthetase 2 [KO:K01915] [EC:6.3.1.2]
EKD16_09835  glnA2; Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
EKD16_19990  glyA2; Serine hydroxymethyltransferase 2 [KO:K00600] [EC:2.1.2.1]
EKD16_11810  gcvP; Glycine dehydrogenase (decarboxylating) [KO:K00281] [EC:1.4.4.2]
EKD16_19980  gcvT; Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
EKD16_09870  lpd; Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
EKD16_19985  gcvH; Glycine cleavage system H protein [KO:K02437]
EKD16_07640  gcl; Glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
EKD16_07630  hyi; Hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
EKD16_07635  garR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
EKD16_09930  garK; Glycerate 2-kinase [KO:K00865] [EC:2.7.1.165]
EKD16_12450  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EKD16_09465  dgoA; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
EKD16_04440  kgd; Multifunctional 2-oxoglutarate metabolism enzyme [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
EKD16_17170  fdhA3; Formate dehydrogenase subunit alpha precursor [KO:K00123] [EC:1.17.1.9]
EKD16_17175  fdnH; Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit [KO:K00124]
EKD16_04515  purU; Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
strr00010  Glycolysis / Gluconeogenesis
strr00020  Citrate cycle (TCA cycle)
strr00030  Pentose phosphate pathway
strr00053  Ascorbate and aldarate metabolism
strr00071  Fatty acid degradation
strr00230  Purine metabolism
strr00250  Alanine, aspartate and glutamate metabolism
strr00260  Glycine, serine and threonine metabolism
strr00620  Pyruvate metabolism
strr00710  Carbon fixation by Calvin cycle
strr00750  Vitamin B6 metabolism
strr00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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