KEGG   PATHWAY: taes00600
Entry
taes00600                   Pathway                                
Name
Sphingolipid metabolism - Triticum aestivum (bread wheat)
Class
Metabolism; Lipid metabolism
Pathway map
taes00600  Sphingolipid metabolism
taes00600

Module
taes_M00100  Sphingosine degradation [PATH:taes00600]
Other DBs
GO: 0006665
Organism
Triticum aestivum (bread wheat) [GN:taes]
Gene
123080394  long chain base biosynthesis protein 2d-like [KO:K00654] [EC:2.3.1.50]
123063208  long chain base biosynthesis protein 2d [KO:K00654] [EC:2.3.1.50]
123098037  long chain base biosynthesis protein 1a [KO:K00654] [EC:2.3.1.50]
123085297  long chain base biosynthesis protein 1a-like [KO:K00654] [EC:2.3.1.50]
123072112  long chain base biosynthesis protein 2d-like isoform X1 [KO:K00654] [EC:2.3.1.50]
123092743  long chain base biosynthesis protein 1a-like [KO:K00654] [EC:2.3.1.50]
123128105  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
123137892  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
123145194  3-dehydrosphinganine reductase TSC10A-like [KO:K04708] [EC:1.1.1.102]
123078606  neutral ceramidase [KO:K12349] [EC:3.5.1.23]
123061533  neutral ceramidase-like isoform X1 [KO:K12349] [EC:3.5.1.23]
123119120  neutral ceramidase-like [KO:K12349] [EC:3.5.1.23]
123101997  neutral ceramidase-like [KO:K12349] [EC:3.5.1.23]
100136985  neutral ceramidase isoform X1 [KO:K12349] [EC:3.5.1.23]
123110118  neutral ceramidase-like isoform X1 [KO:K12349] [EC:3.5.1.23]
123095790  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
123087182  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
123090780  alkaline ceramidase-like [KO:K04711] [EC:3.5.1.-]
123046042  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
123189815  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
123053923  sphingolipid delta(4)-desaturase DES1-like [KO:K04712] [EC:1.14.19.17 1.14.18.5]
123058421  sphinganine C4-monooxygenase 2-like [KO:K04713] [EC:1.14.18.5]
123128378  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123145493  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123044118  very-long-chain aldehyde decarbonylase GL1-9-like [KO:K04713] [EC:1.14.18.5]
123094575  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123187864  very-long-chain aldehyde decarbonylase GL1-9 isoform X1 [KO:K04713] [EC:1.14.18.5]
123130294  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123169355  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123150885  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123169898  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123082207  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123082947  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123082952  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123152471  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123065493  sphinganine C4-monooxygenase 2-like [KO:K04713] [EC:1.14.18.5]
123084208  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123084209  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123099651  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123099994  sphinganine C4-monooxygenase 2-like [KO:K04713] [EC:1.14.18.5]
123152975  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123170742  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123154624  sphinganine C4-monooxygenase 2-like [KO:K04713] [EC:1.14.18.5]
123051999  very-long-chain aldehyde decarbonylase GL1-9-like isoform X1 [KO:K04713] [EC:1.14.18.5]
123138233  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123140739  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123142876  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123160354  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123160900  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123074596  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123164209  sphinganine C4-monooxygenase 1-like [KO:K04713] [EC:1.14.18.5]
123137729  ceramide kinase-like isoform X1 [KO:K04715] [EC:2.7.1.138]
123127902  ceramide kinase-like isoform X1 [KO:K04715] [EC:2.7.1.138]
123144994  ceramide kinase-like isoform X1 [KO:K04715] [EC:2.7.1.138]
123044545  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
123188257  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
123079381  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
123062251  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
123052402  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
123071005  sphingosine kinase 2-like isoform X1 [KO:K04718] [EC:2.7.1.91]
123077232  sphingosine-1-phosphate lyase-like [KO:K01634] [EC:4.1.2.27]
123060230  sphingosine-1-phosphate lyase [KO:K01634] [EC:4.1.2.27]
123068726  sphingosine-1-phosphate lyase-like [KO:K01634] [EC:4.1.2.27]
123045385  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123166431  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123166667  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123079428  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
123096219  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
123049086  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
123086748  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
123121071  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123156898  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123157002  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123181018  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123181424  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123071056  non-lysosomal glucosylceramidase-like [KO:K17108] [EC:3.2.1.45]
123091221  non-lysosomal glucosylceramidase-like isoform X1 [KO:K17108] [EC:3.2.1.45]
123080747  beta-galactosidase-like [KO:K01190] [EC:3.2.1.23]
123072529  beta-galactosidase-like [KO:K01190] [EC:3.2.1.23]
123064876  beta-galactosidase 8-like [KO:K12309] [EC:3.2.1.23]
123142395  beta-galactosidase 8-like isoform X1 [KO:K12309] [EC:3.2.1.23]
123182804  beta-galactosidase 8-like isoform X1 [KO:K12309] [EC:3.2.1.23]
123043688  alpha-galactosidase 3-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123111605  alpha-galactosidase-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123187481  alpha-galactosidase 3-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123046929  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123046940  alpha-galactosidase-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123115440  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123115441  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123101993  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123051556  alpha-galactosidase 3-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123103410  alpha-galactosidase-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123120973  alpha-galactosidase-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123122390  alpha-galactosidase-like isoform X1 [KO:K07407] [EC:3.2.1.22]
123122406  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123181168  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123181169  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123106337  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123124106  alpha-galactosidase-like [KO:K07407] [EC:3.2.1.22]
123187816  beta-hexosaminidase 1-like [KO:K12373] [EC:3.2.1.52]
123080086  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
123133269  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
123062898  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
123098218  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
123049096  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
123180066  beta-hexosaminidase 1-like [KO:K12373] [EC:3.2.1.52]
123182032  beta-hexosaminidase 3-like isoform X1 [KO:K12373] [EC:3.2.1.52]
123071757  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
123105862  beta-hexosaminidase 1-like [KO:K12373] [EC:3.2.1.52]
123041089  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
123185045  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
123055958  beta-hexosaminidase 3-like [KO:K12373] [EC:3.2.1.52]
123092947  beta-hexosaminidase 2-like [KO:K12373] [EC:3.2.1.52]
123111370  prosaposin-like [KO:K12382]
123060305  proactivator polypeptide-like 1 [KO:K12382]
123077317  proactivator polypeptide-like 1 [KO:K12382]
123096477  proactivator polypeptide-like 1 [KO:K12382]
123065456  proactivator polypeptide-like 1 isoform X1 [KO:K12382]
123120365  prosaposin-like [KO:K12382]
123068817  proactivator polypeptide-like 1 [KO:K12382]
123086478  proactivator polypeptide-like 1 [KO:K12382]
123103174  prosaposin-like [KO:K12382]
123143011  proactivator polypeptide-like 1 [KO:K12382]
123160477  uncharacterized protein LOC123160477 [KO:K12382]
123091516  proactivator polypeptide-like 1 [KO:K12382]
Compound
C00065  L-Serine
C00154  Palmitoyl-CoA
C00195  N-Acylsphingosine
C00319  Sphingosine
C00346  Ethanolamine phosphate
C00550  Sphingomyelin
C00836  Sphinganine
C01120  Sphinganine 1-phosphate
C01190  Glucosylceramide
C01290  Lactosylceramide
C01747  Psychosine
C02686  Galactosylceramide
C02934  3-Dehydrosphinganine
C02960  Ceramide 1-phosphate
C03108  D-Glucosylsphingosine
C03272  Globoside
C03405  Lactosylceramide sulfate
C03640  Sphingosyl-phosphocholine
C04730  GM3
C04737  alpha-D-Galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
C04884  N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C04911  D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide
C05681  Ceramide 2-aminoethylphosphonate
C06062  Ceramide phosphoethanolamine
C06124  Sphingosine 1-phosphate
C06125  Sulfatide
C06126  Digalactosylceramide
C06127  Digalactosylceramide sulfate
C06128  GM4
C06135  GA2
C06136  GA1
C12126  Dihydroceramide
C12144  Phytosphingosine
C12145  Phytoceramide
C22467  Gangliotriaosylceramide-II3 sulfate
Reference
PMID:12011104
  Authors
Merrill AH Jr.
  Title
De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.
  Journal
J Biol Chem 277:25843-6 (2002)
DOI:10.1074/jbc.R200009200
Reference
PMID:10652340
  Authors
Tani M, Okino N, Mitsutake S, Tanigawa T, Izu H, Ito M.
  Title
Purification and characterization of a neutral ceramidase from mouse liver. A single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized.
  Journal
J Biol Chem 275:3462-8 (2000)
DOI:10.1074/jbc.275.5.3462
Reference
PMID:11305904
  Authors
Hannun YA, Luberto C, Argraves KM.
  Title
Enzymes of sphingolipid metabolism: from modular to integrative signaling.
  Journal
Biochemistry 40:4893-903 (2001)
DOI:10.1021/bi002836k
Reference
PMID:1495423
  Authors
Merrill AH Jr, Wang E.
  Title
Enzymes of ceramide biosynthesis.
  Journal
Methods Enzymol 209:427-37 (1992)
DOI:10.1016/0076-6879(92)09053-6
Reference
PMID:8457204
  Authors
Hirschberg K, Rodger J, Futerman AH.
  Title
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endoplasmic reticulum in rat liver.
  Journal
Biochem J 290 ( Pt 3):751-7 (1993)
DOI:10.1042/bj2900751
Reference
PMID:10366774
  Authors
Dickson RC, Lester RL.
  Title
Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1438:305-21 (1999)
DOI:10.1016/S1388-1981(99)00068-2
Related
pathway
taes00260  Glycine, serine and threonine metabolism
taes00601  Glycosphingolipid biosynthesis - lacto and neolacto series
taes00603  Glycosphingolipid biosynthesis - globo and isoglobo series
taes00604  Glycosphingolipid biosynthesis - ganglio series
KO pathway
ko00600   
LinkDB

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