KEGG ORTHOLOGY: K01634

ORTHOLOGY: K01634

Entry

K01634                      KO

Symbol

SGPL1, DPL1

Name

sphinganine-1-phosphate aldolase [EC:4.1.2.27]

Pathway

map00600

Sphingolipid metabolism

map01100

Metabolic pathways

map04071

Sphingolipid signaling pathway

Module

M00100

Sphingosine degradation

Reaction

R02464

sphinganine-1-phosphate pamlmitaldehyde-lyase

R06516

sphingosine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)

Disease

H01657

Nephrotic syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K01634  SGPL1, DPL1; sphinganine-1-phosphate aldolase
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K01634  SGPL1, DPL1; sphinganine-1-phosphate aldolase
Enzymes [BR:ko01000]
4. Lyases
  4.1  Carbon-carbon lyases
   4.1.2  Aldehyde-lyases
    4.1.2.27  sphinganine-1-phosphate aldolase
     K01634  SGPL1, DPL1; sphinganine-1-phosphate aldolase

Other DBs

COG:

COG0076

GO:

0008117

Genes

HSA:	8879(SGPL1)

PTR:	466102(SGPL1)

PPS:	100981534(SGPL1)

GGO:	101144014(SGPL1)

PON:	100173995(SGPL1)

NLE:	100590433(SGPL1)

HMH:	116459017(SGPL1)

MCC:	716245(SGPL1)

MCF:	102120317(SGPL1)

MTHB:

126962507

MNI:	105466064(SGPL1)

CSAB:

103216045(SGPL1)

CATY:

105597461(SGPL1)

PANU:

101013622(SGPL1)

TGE:	112631747(SGPL1)

MLEU:

105547459(SGPL1)

RRO:	104661990(SGPL1)

RBB:	108516894(SGPL1)

TFN:	117082709(SGPL1)

PTEH:

111537889(SGPL1)

CANG:

105501550(SGPL1)

CJC:	100403731(SGPL1)

SBQ:	101038539(SGPL1)

CIMI:

108318092(SGPL1)

CSYR:

103253897(SGPL1)

MMUR:

105870187(SGPL1)

LCAT:

123649807(SGPL1)

PCOQ:

105826051(SGPL1)

OGA:	100956120(SGPL1)

MMU:	20397(Sgpl1)

MCAL:

110303128(Sgpl1)

MPAH:

110326438(Sgpl1)

RNO:	286896(Sgpl1)

MCOC:

116074551(Sgpl1)

ANU:	117724427(Sgpl1)

MUN:	110558084(Sgpl1)

CGE:	100761441(Sgpl1)

MAUA:

101843755(Sgpl1)

PROB:

127224005(Sgpl1)

PLEU:

114704742(Sgpl1)

MORG:

121450842(Sgpl1)

MFOT:

126499090

AAMP:

119822663(Sgpl1)

NGI:	103736975(Sgpl1)

HGL:	101700996 101719478(Sgpl1)

CPOC:

100722554(Sgpl1)

CCAN:

109685346(Sgpl1)

DORD:

105986340(Sgpl1)

DSP:	122122281(Sgpl1)

PLOP:

125344130 125346422(Sgpl1)

NCAR:

124985729

MMMA:

107154810(Sgpl1)

OCU:

100338930

OPI:	101517640(SGPL1)

TUP:	102499822(SGPL1)

GVR:

103599741

CFA:	489032(SGPL1)

CLUD:

112651391(SGPL1)

VVP:	112924063(SGPL1)

VLG:	121487800(SGPL1)

NPO:	129509595(SGPL1)

AML:	100473418(SGPL1)

UMR:	103667796(SGPL1)

UAH:	113259146(SGPL1)

UAR:	123782879(SGPL1)

ELK:

111145250

LLV:

125084649

MPUF:

101686151(SGPL1)

MNP:	132016409(SGPL1)

MLK:	131828863(SGPL1)

NVS:	122900762(SGPL1)

EJU:	114214092(SGPL1)

ZCA:	113923471(SGPL1)

MLX:	118018400 118019146

NSU:	110589181(SGPL1)

LWW:	102738934(SGPL1)

FCA:	101096919(SGPL1)

PYU:	121036747(SGPL1)

PCOO:

112854677(SGPL1)

PBG:	122492855(SGPL1)

PVIV:

125147460(SGPL1)

LRUF:

124506873

PTG:	102951165(SGPL1)

PPAD:

109264372(SGPL1)

PUC:

125933270

AJU:

106967167

HHV:	120232509(SGPL1)

BTA:	522515(SGPL1)

BOM:	102282135(SGPL1)

BIU:	109553759(SGPL1)

BBUB:

102398975(SGPL1)

BBIS:

104997553(SGPL1)

CHX:	100861080(SGPL1)

OAS:	101111155(SGPL1)

BTAX:

128047645(SGPL1)

ODA:	120865334(SGPL1)

CCAD:

122446448(SGPL1)

MBEZ:

129555744(SGPL1)

SSC:	100525187(SGPL1)

CFR:	102505966(SGPL1)

CBAI:

105066338(SGPL1)

CDK:	105099866(SGPL1)

VPC:	102535443(SGPL1)

BACU:

103014591(SGPL1)

BMUS:

118882359(SGPL1)

LVE:	103076098(SGPL1)

OOR:	101288258(SGPL1)

DLE:	111183476(SGPL1)

PCAD:

102993074(SGPL1)

PSIU:

116741252(SGPL1)

NASI:

112413524(SGPL1)

ECB:	100072755(SGPL1)

EPZ:	103567305(SGPL1)

EAI:	106830637(SGPL1)

MYB:	102240699(SGPL1)

MYD:	102771234(SGPL1)

MMYO:

118670109(SGPL1)

MLF:	102435463(SGPL1)

PKL:	118719138(SGPL1)

EFUS:

103289492(SGPL1)

MNA:	107543943(SGPL1)

DRO:	112305436(SGPL1)

SHON:

118993444(SGPL1)

AJM:	119038201(SGPL1) 119049495

PDIC:

114497770(SGPL1)

PHAS:

123820965(SGPL1)

MMF:	118616565 118632068(SGPL1)

PPAM:

129069912(SGPL1)

HAI:	109372259(SGPL1)

RFQ:	117035822(SGPL1)

PALE:

102889997(SGPL1)

PGIG:

120609498(SGPL1)

PVP:	105300140(SGPL1)

RAY:	107498214(SGPL1)

MJV:	108398007(SGPL1)

TOD:	119234907(SGPL1)

SARA:

101546993(SGPL1)

SETR:

126030876(SGPL1)

LAV:	100672802(SGPL1)

TMU:

101361203

ETF:	101638049 101663178

DNM:	101414030(SGPL1)

MDO:	100030674(SGPL1)

GAS:	123232964(SGPL1)

SHR:	100931521(SGPL1)

AFZ:

127551957

PCW:	110213943(SGPL1)

OAA:	100077675(SGPL1)

GGA:	423714(SGPL1)

PCOC:

116235036(SGPL1)

MGP:	100545432(SGPL1)

CJO:	107315742(SGPL1)

TPAI:

128077627(SGPL1)

LMUT:

125693589(SGPL1)

NMEL:

110399329(SGPL1)

APLA:

101804964(SGPL1)

ACYG:

106030688(SGPL1)

CATA:

118243293(SGPL1)

AFUL:

116491232(SGPL1)

TGU:	100224512(SGPL1)

LSR:	110469898(SGPL1)

SCAN:

103823720(SGPL1)

PMOA:

120496115(SGPL1)

OTC:	121348083(SGPL1)

PRUF:

121365703(SGPL1)

GFR:	102039902(SGPL1)

FAB:	101820936(SGPL1)

OMA:	130255208(SGPL1)

PHI:	102101422(SGPL1)

PMAJ:

107207015(SGPL1)

CCAE:

111931425(SGPL1)

CCW:	104690130(SGPL1)

CBRC:

103623709(SGPL1)

ETL:	114062204(SGPL1)

ZAB:	102064254(SGPL1)

ACHL:

103806691(SGPL1)

SVG:	106857313(SGPL1)

MMEA:

130585284(SGPL1)

HRT:	120755615(SGPL1)

FPG:	101910637(SGPL1)

FCH:	102055917(SGPL1)

CLV:	102090294(SGPL1)

EGZ:	104122649(SGPL1)

NNI:	104013498(SGPL1)

PCRI:

104038796(SGPL1)

PLET:

104625071(SGPL1)

EHS:	104502559(SGPL1)

PCAO:

104043226(SGPL1)

ACUN:

113481903(SGPL1)

TALA:

104355881(SGPL1)

PADL:

103918471(SGPL1)

AFOR:

103908217(SGPL1)

ACHC:

115348224(SGPL1)

HALD:

104325626(SGPL1)

HLE:	104839571(SGPL1)

AGEN:

126043106

GCL:

127017967

CCRI:

104166051(SGPL1)

CSTI:

104559877(SGPL1)

CMAC:

104477003(SGPL1)

MUI:	104548060(SGPL1)

BREG:

104639554(SGPL1)

FGA:	104080411(SGPL1)

GSTE:

104257928(SGPL1)

LDI:	104342711(SGPL1)

MNB:	103775548(SGPL1)

OHA:	104329783(SGPL1)

NNT:	104411254(SGPL1)

SHAB:

115608440(SGPL1)

DPUB:

104308863(SGPL1)

PGUU:

104463865(SGPL1)

ACAR:

104521086(SGPL1)

CPEA:

104389241(SGPL1)

AVIT:

104267791(SGPL1)

CVF:	104291679(SGPL1)

RTD:	128910945(SGPL1)

CUCA:

104054773(SGPL1)

TEO:	104374967(SGPL1)

BRHI:

104495576(SGPL1)

AAM:	106500227(SGPL1)

AROW:

112968634(SGPL1)

NPD:	112952233(SGPL1)

TGT:	104576248(SGPL1)

DNE:	112985875(SGPL1)

SCAM:

104144527(SGPL1)

ASN:	102373526(SGPL1)

AMJ:	102574782(SGPL1)

CPOO:

109312556(SGPL1)

GGN:	109290969(SGPL1)

PSS:	102456423(SGPL1)

CMY:	102942363(SGPL1)

CCAY:

125640123(SGPL1)

DCC:	119859247(SGPL1)

CPIC:

101947242(SGPL1)

TST:	117879845(SGPL1)

CABI:

116826182(SGPL1)

MRV:	120369102(SGPL1)

ACS:	100565427(sgpl1)

ASAO:

132771166(SGPL1)

PVT:	110073680(SGPL1)

SUND:

121927369(SGPL1)

PBI:

103062874

PMUR:

107292169(SGPL1)

CTIG:

120297649(SGPL1)

TSR:	106549172(SGPL1)

PGUT:

117670676(SGPL1)

APRI:

131200721(SGPL1)

PTEX:

113444630(SGPL1)

NSS:	113421036(SGPL1)

VKO:	123018426(SGPL1)

PMUA:

114597231(SGPL1)

PRAF:

128413949(SGPL1)

ZVI:	118096640(SGPL1)

HCG:	128349560(SGPL1)

GJA:	107120523(SGPL1)

STOW:

125437837(SGPL1)

EMC:	129331808(SGPL1)

XLA:	100037007(sgpl1.L)

XTR:	100379782(sgpl1)

NPR:	108803085(SGPL1)

RTEM:

120908960(SGPL1)

BBUF:

121004076 121004077

BGAR:

122944426 122944623(SGPL1)

MUO:	115470392(SGPL1)

GSH:	117358967(SGPL1)

DRE:	100037312(sgpl1)

SRX:	107726953 107743499(sgpl1)

SANH:

107655444 107666355

SGH:	107559334 107601887

CCAR:

109078960 109090724

CAUA:

113056956 113072492 113083901 113112661

CGIB:

127970262 128026194

PTET:

122356658(sgpl1)

LROH:

127175226(sgpl1)

OMC:	131552628(sgpl1)

PPRM:

120473269(sgpl1)

RKG:	130089628(sgpl1)

MAMB:

125276932(sgpl1)

CIDE:

127524405

MASI:

127412264 127414181

TROS:

130559630(sgpl1)

TDW:	130432052(sgpl1)

MANU:

129415680(sgpl1)

IPU:

108263680

IFU:	128605775(sgpl1)

PHYP:

113539696(sgpl1)

SMEO:

124399979(sgpl1)

TFD:	113636294(sgpl1)

TVC:	132847387(sgpl1)

AMEX:

103028047(sgpl1)

CMAO:

118810500(sgpl1)

EEE:	113585228(sgpl1)

CHAR:

105890973(sgpl1)

TRU:	101069731(sgpl1)

TFS:	130533892(sgpl1)

TNG:	GSTEN00024535G001

LCO:	104921879(sgpl1)

NCC:	104952733(sgpl1)

TBEN:

117499568(sgpl1)

CGOB:

115020031(sgpl1)

PGEO:

117459919(sgpl1)

GACU:

117552328(sgpl1)

EMAC:

134858713(sgpl1)

ELY:	117248367(sgpl1)

EFO:	125903141(sgpl1)

PLEP:

121954553(sgpl1)

SLUC:

116039393(sgpl1)

ECRA:

117960081(sgpl1)

ESP:	116683579(sgpl1)

PFLV:

114571836(sgpl1)

GAT:	120820242(sgpl1)

PPUG:

119214035(sgpl1)

AFB:	129092295(sgpl1)

CLUM:

117743691(sgpl1)

PSWI:

130207540(sgpl1)

MSAM:

119917615(sgpl1)

SCHU:

122884856(sgpl1)

CUD:	121510935(sgpl1)

ALAT:

119033549(sgpl1)

MZE:	101474325(sgpl1)

ONL:	100702609(sgpl1)

OAU:	116318762(sgpl1)

OLA:	101156524(sgpl1)

OML:	112140772 112161992(sgpl1)

CSAI:

133464140(sgpl1)

XMA:	102224894(sgpl1)

XCO:	114138416(sgpl1)

XHE:	116713366(sgpl1)

PRET:

103477120(sgpl1)

PFOR:

103148240(sgpl1)

PLAI:

106936321(sgpl1)

PMEI:

106930451(sgpl1)

GAF:	122842270(sgpl1)

PPRL:

129352618(sgpl1)

CVG:	107088771(sgpl1)

CTUL:

119782912(sgpl1)

GMU:	124859555(sgpl1)

NFU:	107374430(sgpl1)

KMR:	108240661(sgpl1)

ALIM:

106532720(sgpl1)

NWH:	119410902(sgpl1)

AOCE:

111573095(sgpl1)

MCEP:

125018407(sgpl1)

CSEM:

103387462(sgpl1)

POV:	109633624(sgpl1)

SSEN:

122781789(sgpl1)

HHIP:

117775328(sgpl1)

HSP:	118118955(sgpl1)

SMAU:

118283523(sgpl1)

LCF:

108886254

SDU:	111220576(sgpl1)

SLAL:

111669498(sgpl1)

XGL:	120796815(sgpl1)

HCQ:	109523058(sgpl1)

SSCV:

125978425

SBIA:

133509575(sgpl1)

PEE:	133409413(sgpl1)

PTAO:

133485354(sgpl1)

BPEC:

110162189(sgpl1)

MALB:

109953937 109958455

BSPL:

114870728(sgpl1)

SJO:	128372596(sgpl1)

SASA:

106576820 106604578

STRU:

115153009 115194002

OTW:	112252664 112252804(sgpl1)

OMY:	110502271 110526362(sgpl1)

OGO:	124038111 124041437

ONE:	115113388 115135306

OKI:	109889773 109899586

OKE:	118369507 118402054

SALP:

111978537(sgpl1)

SNH:	120017520(sgpl1) 120046462

CCLU:

121553655(sgpl1) 121568859

ELS:	105028651(sgpl1)

SFM:	108932886(sgpl1)

PKI:	111849017(sgpl1)

AANG:

118217946(sgpl1)

LOC:	102698006(sgpl1)

PSPA:

121326248(sgpl1)

ARUT:

117418061(sgpl1)

PSEX:

120530686(sgpl1)

LCM:	102363827(SGPL1)

CMK:	103181428(sgpl1)

RTP:	109930251(sgpl1)

CPLA:

122541931(sgpl1)

HOC:	132835016(sgpl1)

LERI:

129712964(sgpl1)

PMRN:

116944488(SGPL1)

BFO:	118405670 118411399

BBEL:

109465255 109481352

CIN:	100175941 100185245

SCLV:

120328469

SPU:	585628 585643

LPIC:

129281171 129281215 129281216

APLC:

110980783 110991175

AJC:	117109967 117109968

SKO:	100370334 102808498

DME:	Dmel_CG8946(Sply)

DER:

6548277

DSE:

6609548

DSI:	Dsimw501_GD25496(Dsim_GD25496)

DYA:	Dyak_GE14215

DAN:

DSR:

DPO:

DPE:

DMN:	108160415 117185927 117189805 117189812 117190454 117191960 117191962 117191976

DWI:

6646017

DGR:

6560803

DMO:	Dmoj_GI21004

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108369391 108372333

AOQ:

129245963

TDA:	119678792 119679280

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:	110673984 5577517

AALB:

109430336

CQU:	CpipJ_CPIJ018230

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:	111421713 111423251

BMOR:

101743812

BMAN:

114247370

MSEX:

115445728 119188385

DPL:	KGM_209830 KGM_209831

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105385432 105388046 105396450

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:	128993327 128993406

PHU:	Phum_PHUM424550

FOC:

TPAL:

ZNE:

SGRE:

BROR:

IEL:

FCD:	110844136 110844543 110845186

DPX:	DAPPUDRAFT_317407

DMK:

116929603

DPZ:

124311095

PVM:	113800280 113829804 113829809

PJA:	122242638 122253635

PCHN:

PMOO:

HAME:

PCLA:

CQD:	128687474 128687520 128690856

PTRU:

123504653 123517088

ESN:	126988717 127007065

MNZ:	135200893 135202287

HAZT:

108675494 108679365

EAF:	111697970 111704349

LSM:

121116381

TCF:	131882779 131884265

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

PMEO:

CEL:	CELE_B0222.4(spl-2) CELE_Y66H1B.4(spl-1)

CBR:	CBG_10544(Cbr-spl-1) CBG_19207(Cbr-tag-38)

CRQ:	GCK72_016360 GCK72_017178

NAI:	NECAME_00438 NECAME_13013 NECAME_15967

BMY:	BM_BM11004(Bma-spl-1) BM_BM18217(Bm18217)

LOA:	LOAG_00467 LOAG_02025

LGI:	LOTGIDRAFT_129959 LOTGIDRAFT_228978

PVUL:

126812025 126827602

PCAN:

112561444 112568065

BGT:

106056473

GAE:	121377338 121379193

HRF:	124137942 124143772

HRJ:	124261393 124274207

CRG:	105325808 105338792

CVN:	111121731 111121732 111124154

CANU:

128167070 128180538

OED:

125645499

MYI:	110443498 110458188

PMAX:

117316790 117325378

MCAF:

127707976 127723178

MMER:

123540733 123564410

RPHI:

132732755 132733709 132756223

DPOL:

127857122 127858788 127868528 127876593

OBI:

106879041

OSN:

115211803

LAK:	106154808 106164601 106177120

SMM:	Smp_154950

SHX:	MS3_00002621(SGPL1_1)

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114525496 114537793 114537948

XEN:	124450375 124453235

HMG:

100205190

HSY:

130628856

TAD:	TRIADDRAFT_28705

AQU:	100640497 100640966

ATH:	AT1G27980(DPL1)

ALY:

9326816

CRB:

17898342

CSAT:

104741406 104757133 104776851

EUS:	EUTSA_v100093780m

BRP:

103835360

BNA:	106359177 106389564

BOE:

106335335

RSZ:	108818788 108822716

THJ:

104820527

CIT:

102622175

CIC:	CICLE_v10031168mg

PVY:

MINC:

TCC:

GRA:

GHI:	107916557 107922384

GAB:

108461878

HSYR:

120118018 120179543

DZI:	111287330 111318017

GMX:	100794395 100794743

GSJ:	114385628 114395434

PVU:	PHAVU_008G017200g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:	131608995 131634983

ADU:

107486171

AIP:

107635623

AHF:	112744829 112798119

LANG:

109354787

PCIN:

129319349

QSA:	O6P43_023824

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SSTN:

SDUL:

CANN:

LBB:

NTA:

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:	110871775 110871788

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110690522 110711278

ATRI:

MOF:

NNU:

MING:

TSS:	122656597 122670423

PSOM:

113271643 113281020

OSA:

4326459

DOSA:

Os01t0100900-01(Os01g0100900)

OBR:

OGL:

BDI:

ATS:

TDC:	119267050 119274862

TAES:

123060230 123068726 123077232

TUA:	125542698 125542721

LPER:

LRD:

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	122008198 122017796

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_410502 SELMODRAFT_411607

PPP:

112277495

CRE:	CHLRE_03g155051v5

VCN:	VOLCADRAFT_60125

CSL:	COCSUDRAFT_64705

CVR:	CHLNCDRAFT_144988

APRO:

F751_3955

OLU:	OSTLU_119543(sgpL)

OTA:	OT_ostta02g02240

BPG:	Bathy14g01500

MIS:	MICPUN_54933(SGPL)

MPP:	MICPUCDRAFT_70682(SGPL)

CME:	CYME_CMT631C

SCE:	YDR294C(DPL1)

SEUB:

DI49_0471

SPAO:

SPAR_D04850

KLA:	KLLA0_C10505g

KMX:	KLMA_30426(DPL1)

LTH:	KLTH0G06182g

VPO:	Kpol_1004p70

ZRO:	ZYRO0G16918g

CGR:	CAGL0H01309g

NCS:	NCAS_0F02560(NCAS0F02560)

NDI:	NDAI_0C04060(NDAI0C04060)

TPF:	TPHA_0D01840(TPHA0D01840)

TBL:	TBLA_0A02880(TBLA0A02880)

TGB:	HG536_0E03280

TDL:	TDEL_0E03170(TDEL0E03170)

KAF:	KAFR_0E01380(KAFR0E01380)

KNG:	KNAG_0M01640(KNAG0M01640)

ZMK:	HG535_0A04280

PPA:	PAS_chr4_0598

DHA:	DEHA2D16192g

PIC:	PICST_87778(DPL1)

PGU:	PGUG_00600

SPAA:

SPAPADRAFT_140932

LEL:	PVL30_003648(DPL1)

CAL:	CAALFM_C303680WA(CaO19.6951)

CTP:	CTRG_02474

COT:	CORT_0C02280

CDU:	CD36_83680

CTEN:

CANTEDRAFT_110649

YLI:	YALI0E28237g

CLU:	CLUG_03146

CLUS:

A9F13_12g01782

CAUR:

CJI96_0002680

SLB:	AWJ20_2886(DPL1)

PKZ:	C5L36_0B11290

BNN:	FOA43_003787

BBRX:

BRETT_000488

OPA:	HPODL_00811

SLUD:

SCDLUD_004612

NCR:

NCU06761

NTE:	NEUTE1DRAFT117442(NEUTE1DRAFT_117442)

SMP:	SMAC_06752

PAN:	PODANSg6633

PBEL:

QC761_307920(DPL1)

PPSD:

QC762_307920(DPL1)

PPSP:

QC763_307920(DPL1)

PPSA:

QC764_307920(DPL1)

TTT:	THITE_2124498

MTM:	MYCTH_2312755

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_890

SSCK:

SPSK_01591

FGR:	FGSG_04413

FPU:	FPSE_06335

FPOA:

FPOAC1_006884

FVN:	FVRRES_07512

FVR:	FVEG_11249

FOX:	FOXG_13821

NHE:	NECHADRAFT_63095

FFC:	NCS54_01070100

FKR:	NCS57_01063900

FMU:	J7337_011883

TRE:	TRIREDRAFT_79835

TRR:	M419DRAFT_25900

MAW:

MAJ:

PCHM:

CMT:

AMUS:

PLJ:	VFPFJ_03811

PTKZ:

JDV02_002562(DPL1)

VAL:	VDBG_05290

VDA:	VDAG_06941

CFJ:	CFIO01_11081

CHIG:

CH63R_10073

SAPO:

SAPIO_CDS1051

ELA:	UCREL1_11272

PFY:	PFICI_11254

SSL:	SS1G_10382

BFU:	BCIN_14g03790(Bcdpl1)

MBE:

MBM_04623

PSCO:

LY89DRAFT_644338

GLZ:	GLAREA_03203

ANI:	ANIA_01989

AFM:	AFUA_4G10470

ACT:	ACLA_049670

NFI:	NFIA_105600

AOR:	AO090003001164 AO090010000721

ANG:	An04g06200

AFV:	AFLA_000503 AFLA_014220

ALUC:

AKAW2_51585A

ACHE:

ACHE_10781S

APUU:

APUU_21065S

PCS:	N7525_005047

PDP:	PDIP_24790

POU:	POX_f08045

TMF:	EYB26_005248

TRG:	TRUGW13939_02748

CIM:	CIMG_01453

CPW:	CPC735_049880

URE:	UREG_05143

PBL:	PAAG_02604

PBN:	PADG_01622

ABE:

ARB_03741

TVE:

TRV_05007

AJE:	HCAG_06103

BGH:	BDBG_02319

PNO:	SNOG_07644

PTE:

PTT_10694

BZE:	COCCADRAFT_103816

BSC:	COCSADRAFT_142688

BOR:	COCMIDRAFT_34016

AALT:

CC77DRAFT_946178

ARAB:

EKO05_0006184

ZTR:	MYCGRDRAFT_34547

PFJ:	MYCFIDRAFT_209530

FFU:	CLAFUR5_00891

CBET:

CB0940_00883

BCOM:

BAUCODRAFT_35090

NPA:	UCRNP2_8200

TML:	GSTUM_00005905001

CNE:

CNH00560

CNB:

CNBL0540

CNG:	CNAG_05389

CGI:	CGB_L0300W

CDEU:

CNBG_4463

TMS:	TREMEDRAFT_39283

TASA:

A1Q1_07487

CCAC:

CcaHIS019_0102680(DPL1)

TVS:	TRAVEDRAFT_141971

DSQ:	DICSQDRAFT_99263

PCO:	PHACADRAFT_258725

SHS:	STEHIDRAFT_171050

HIR:	HETIRDRAFT_62130

PSQ:	PUNSTDRAFT_98981

ADL:	AURDEDRAFT_111351

FME:	FOMMEDRAFT_122747

GTR:	GLOTRDRAFT_58245

RSX:	RhiXN_06422

LBC:	LACBIDRAFT_189158

CCI:	CC1G_02303

ABP:	AGABI1DRAFT116649(AGABI1DRAFT_116649)

ABV:	AGABI2DRAFT196082(AGABI2DRAFT_196082)

PCUB:

JR316_0001791

MRR:	Moror_15394

E1B28_000391

SCM:	SCHCO_02634051(SCHCODRAFT_02634051)

CPUT:

CONPUDRAFT_81389

SLA:	SERLADRAFT_466391

WSE:	WALSEDRAFT_29699

WIC:	J056_001136

UMA:	UMAG_10175

PFP:	PFL1_03119

SGRA:

MGL:

MRT:

MSYM:

PGR:	PGTG_02329

PTRC:

PtA15_2A878

PSTR:

Pst134EA_005539

MLR:	MELLADRAFT_51096

MBR:	MONBRDRAFT_14889 MONBRDRAFT_32346

SRE:	PTSG_00685 PTSG_10944

DDI:	DDB_G0280183(sglB) DDB_G0282819(sglA)

DPP:	DICPUDRAFT_147400 DICPUDRAFT_75040

DFA:	DFA_08508(sglB)

EHI:	EHI_039350(73.t00003)

EDI:	EDI_260590

EIV:	EIN_227360

ACAN:

ACA1_068140 ACA1_112890

TET:	TTHERM_00138450 TTHERM_00259410

PTM:	GSPATT00013947001 GSPATT00020471001

SMIN:

v1.2.028863.t1(symbB.v1.2.028863.t1)

PTI:	PHATRDRAFT_15730

TPS:	THAPSDRAFT_29322

NGD:	NGA_0126200

AAF:	AURANDRAFT_27290

PIF:	PITG_00380

PSOJ:

PHYSODRAFT_346729

EHX:	EMIHUDRAFT_102422 EMIHUDRAFT_316847

GTT:	GUITHDRAFT_97529

TBR:	Tb927.6.3630

TBG:	TbgDal_VI3390

TCR:	506941.150 511511.150

LMA:	LMJF_30_2350(SPL)

LIF:	LINJ_30_2360(SPL)

LDO:	LDBPK_302360

LMI:	LMXM_29_2350

LBZ:	LBRM_30_2300

LPAN:

LPMP_302310(SPL)

NGR:	NAEGRDRAFT_1152

LAB:	LA76x_2694

LAQ:	GLA29479_3544

LCP:	LC55x_2632

LGU:	LG3211_2437

LEZ:

GLE_2379

LEM:	LEN_2675(gadB)

LYA:	RDV84_20410

THT:	E2K93_06485

SAGA:

M5M_15855

HJA:	BST95_13680

HALC:

EY643_08580

ALG:	AQULUS_00390

LPN:	lpg2176(legS2)

LPH:

LPV_2428

LPO:

LPO_2245

LPU:	LPE509_00922

LPM:	LP6_0786(legS2)

LPF:

LPP:

LPC:

LPA:

LPE:

LFA:

LHA:

LCJ:	NCTC11976_02944(gadB)

LWA:	SAMEA4504053_2450(gadA)

LANT:

TUM19329_20220

BPS:	BPSS2021 BPSS2025

BPM:	BURPS1710b_A1139 BURPS1710b_A1143

BPL:	BURPS1106A_A2756 BURPS1106A_A2761

BPD:	BURPS668_A2912 BURPS668_A2918

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_II2175 BP1026B_II2179

BPQ:	BPC006_II2722 BPC006_II2728

BPK:	BBK_4772 BBK_4776

BPSH:

DR55_5696 DR55_5700

BPSA:

BBU_3973 BBU_3977

BPSO:

X996_5501 X996_5505

BUT:	X994_5058 X994_5062

BTE:	BTH_II0309 BTH_II0311

BTQ:	BTQ_3603 BTQ_3605

BTJ:	BTJ_4639 BTJ_4641

BTZ:	BTL_5427 BTL_5429

BTD:

BTI_4975

BTV:	BTHA_4774 BTHA_4776

BTHE:

BTHM:

BTHA:

BTHL:

BOK:

BOC:

BUU:	WS70_27570

BSAV:

WS86_29315

BHG:	I6G56_28155

BUD:	AQ610_30605

BGD:	bgla_1p0780

BUL:

BW21_4504

AXY:	AXYL_05515

APES:

FOC84_18295

BOZ:	DBV39_12700

VPD:	VAPA_2c03780

MASY:

DPH57_25035

EHB:	E7V67_021950

ETB:	N7L95_08570

MESM:

MMEI:

PLA:

PMOB:

PECT:

BN1012_Phect1456 BN1012_Phect2340

RBS:	RHODOSMS8_00369

SFD:	USDA257_c18320(mfnA)

SAME:

SAMCFNEI73_pB0197

RAD:	CO657_24840

BVZ:	BRAD3257_7310 BRAD3257_7358

STAR:

G3545_14815

RBM:

TEF_04565

PZU:

PHZ_c2240

TSV:	DSM104635_02109(gadB)

SUAM:

BOO69_18715

THAA:

CFI11_20965

TMD:	KUV46_13740

THAS:

C6Y53_02860

HDH:	G5B40_10980

GAK:

HNE:

CBOT:

PARP:

SMIC:

SAND:

ELI:

ERK:	CD351_05480

RFL:

Rmf_25640

SRF:	LHU95_00150

SHUM:

STHU_32730

SVC:	STVA_18840

STEL:

STAQ_29470

HADH:

FRZ61_46620

HFL:	PUV54_09105

TMK:	QGN29_00915

DAL:

Dalk_0154

DWD:	DSCW_39480

DALK:

DSCA_39280

DBR:

Deba_3041

MXA:

MXAN_2880

MSD:	MYSTI_03347

MYM:	A176_001849 A176_004135

MFB:	MFUL124B02_18080

MYX:	QEG98_15330

MFU:	LILAB_22125 LILAB_33085

MMAS:

MYMAC_002834 MYMAC_004916

SUR:	STAUR_2136 STAUR_3081

AGE:	AA314_07834 AA314_09215

AVM:	JQX13_06505 JQX13_28840

MBD:	MEBOL_002274 MEBOL_006543

CFUS:

CYFUS_004126 CYFUS_009104

CCRO:

CMC5_063070

SAMY:

DB32_000612 DB32_008616

LLU:	AKJ09_04347

HOH:	Hoch_0159 Hoch_3073

NANN:

BSED:

PCAY:

BBAE:

FHL:	OE105_01745

PBD:	PBOR_26510

ACUR:

JZ785_18820

STH:

STH1274

MNM:	MNVM_03430

MJD:	JDM601_1548(gadB)

MTER:

4434518_01448(gadB_1)

MMIN:

MMIN_31470

MHIB:

MHIB_10000

MHER:

K3U94_08490

MVM:	MJO54_08555

NOD:	FOH10_04975

RER:	RER_34650 RER_58030

REY:	O5Y_15820 O5Y_27785

REB:	XU06_16050

RQI:	C1M55_17060

RHW:	BFN03_18960

RHOD:

AOT96_27315

RTM:	G4H71_00635

RGO:	KYT97_05965

REQ:

REQ_04780

GBR:

Gbro_3373

GOQ:	ACH46_07650

GOC:	CXX93_15080

GIT:	C6V83_08190

GOM:	D7316_03618

GAM:	GII34_21070

GPD:	GII33_20805

GOI:	LK459_20355

GSI:	P5P27_06835

DIT:	C3V38_13925

DIZ:	CT688_08120

DPC:	A6048_08385

DLU:	A6035_07970

DKN:	NHB83_07690

TOY:	FO059_17640

SALB:

XNR_4310

SFI:

SFUL_2214

SCYE:

R2B67_25070

SSX:	SACTE_2060

SFA:

Sfla_4243

STRP:

F750_2469

SKY:	D0C37_23270

SRJ:

SRO_7174

SNK:	CP967_23040

SGF:	HEP81_07504

SBAT:

G4Z16_08485

SVD:	CP969_04460

SVIO:

HWN34_21750

SLAI:

P8A22_26110

KSK:

KSE_23010

KIS:	HUT16_09720

ABRY:

NYE86_12380

AGLA:

OIE69_31010

LXL:	KDY119_01859(dpl1)

LEIF:

HF024_07410

LSE:	F1C12_05895

MPRT:

ET475_10665

MCHN:

HCR76_12755

MRN:	K8F61_17885

MELY:

L2X98_30670

MSUW:

GCM10025863_17500

MRG:	SM116_03150

MEST:

PTQ19_03585

MVD:	AWU67_02915

AGY:	ATC03_07420

AGM:	DCE93_04200

AARC:

AMAU:

ASOI:

AMAV:

ALAV:

AIL:	FLP10_14765

SALC:

C2138_08525

SALA:

ESZ53_13650

SALD:

FVA74_08235

HUW:	FPZ11_05955

LYD:	D7I47_01705

LYK:	FLP23_06185

LTR:	EVS81_05355

LDN:	H9L06_04625

LVI:	G7068_06030

LARI:

KI794_04450

LRP:	MUN76_13985

AGG:	C1N71_04870

HEH:	L3i23_22410

NAEI:

GCM126_04920

ARM:

ART_2331

AAQ:	AOC05_13735

APOA:

J0916_13155

JDE:

Jden_1646

YIM:	J5M86_14645

IDO:	I598_0125(gadB_1)

CET:	B8281_15685

CCEU:

CBR64_15625

CPRT:

FIC82_014600

CELH:

GXP71_06810

CWN:	NP075_06370

OEK:	FFI11_016170

JTE:	ASJ30_13685

JAY:	H7A72_13910

PHW:	G7075_14725

PEI:	H9L10_15285

TED:	U5C87_02035

SERJ:

SGUI_2971

ORN:	DV701_10390

ORZ:	FNH13_00210

OCP:	NF557_16640

HALT:

RHAL:

RSUA:

NCA:

NDK:	I601_0536(gadB)

NOI:	FCL41_13730

NOO:	FE634_17725

NSN:	EXE58_04525

NANO:

G5V58_18640

NMES:

H9L09_07180

NARO:

CFH99_06165

NOQ:	LN652_16915

NPC:	KUV85_17095

NMAR:

HPC71_17945

NFC:	KG111_03485

PSIM:

KR76_21575

AEZ:	C3E78_03180

AEB:	C6I20_12830

AEF:	GEV26_03085

ASEZ:

H9L21_13220

ADB:	NP095_13165

AWN:	NQV15_02730

MUZ:	H4N58_11325

SGRG:

L0C25_06960

KFL:

Kfla_3408

KQI:	F1D05_04935

THAO:

NI17_019425

NCG:	KGD84_21835

TCU:	Tcur_2562 Tcur_3961

ACTW:

AMAZ:

ACIR:

SPIQ:

SRO:

NOA:	BKM31_47720

NOW:	GBF35_49725

NCX:	Nocox_40465(gadB)

NGN:	LCN96_54410

NFS:	OIE67_49565

TBI:

Tbis_1873

MHAI:

OHB01_32870

BSD:	BLASA_3988

SVI:	Svir_22660

SACC:

EYD13_12625(gadB)

AMD:

AMN:

AMM:

AMZ:

AOI:

AJA:	AJAP_20655

AMQ:	AMETH_2982

AMYC:

CU254_20365

AMYB:

BKN51_10965

AAB:	A4R43_11355

AMYY:

YIM_27870(gadA)

AORI:

AACD:

APRT:

AROO:

ATHM:

ARHD:

PBRO:

APRE:

AMI:

SESP:

SSYI:

KPHY:

PMAD:

UME:	RM788_38955

STP:	Strop_0389

SAQ:

Sare_0460

MAU:	Micau_5575

MIL:

MICB:

MTUA:

MICH:

MTEM:

MCAB:

MSAG:

VMA:	VAB18032_01380

MCRA:

ID554_18715

VER:	HUT12_28665

MENO:

MCHL:

MFEU:

MPRN:

MHAW:

AMS:

AFS:

AIH:	Aiant_48910

ACTR:

Asp14428_39100

ACTL:

L3i22_005780

ASIC:

Q0Z83_082690

AOU:	ACTOB_000561

PLK:	CIK06_03865

PLAB:

C6361_26930

PLAT:

C6W10_25090

PSUU:

Psuf_039840

ATL:	Athai_45020

ASER:

Asera_29650

PRY:	Prubr_16510

CATI:

CS0771_02040

DVC:	Dvina_50035

DFU:	Dfulv_44620

DROS:

DAUR:

DMAT:

CCAZ:

ABAI:

CWO:

AYM:	YM304_15200

ATQ:	GH723_00780

AQZ:	KSP35_04460 KSP35_23235

IAM:	HC251_03085 HC251_10790

IMA:	PO878_03070

DHI:	LH044_02595 LH044_03170 LH044_08790

RRS:	RoseRS_1072 RoseRS_2597

RCA:	Rcas_1867 Rcas_2190

CAU:

Caur_2084

CHL:	Chy400_2247

CAP:	CLDAP_34610

PBF:	CFX0092_A3001

KBS:	EPA93_02085

TBH:	Tbon_05750

TFLA:

O0235_08240

THUG:

KNN16_06130 KNN16_06155

UAM:	UABAM_05161

TPX:	Turpa_2184

HHY:	Halhy_0215

SGN:	SGRA_1062(gadB)

AUP:	AsAng_0017340

AFU:	AF_1323 AF_2295

AFG:	AFULGI_00014340 AFULGI_00025940

GAC:

GACE_2180

GAH:	GAH_00254 GAH_00423

PTO:

PTO0150

FAC:	FACI_IFERC01G1858

FAI:

FAD_0824

APE:	APE_0020.1 APE_2267.1

ACJ:	ACAM_0011 ACAM_1418

SAI:

SACN:

SACR:

SACS:

SACD:

PAS:

POG:

VMO:

Reference

PMID:11018465

Authors

Van Veldhoven PP, Gijsbers S, Mannaerts GP, Vermeesch JR, Brys V

Title

Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22(1).

Journal

Biochim Biophys Acta 1487:128-34 (2000)
DOI:10.1016/S1388-1981(00)00079-2

Sequence

[hsa:8879]

LinkDB

DBGET integrated database retrieval system