Prionailurus bengalensis (leopard cat): 122495851
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Entry
122495851 CDS
T07574
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg01522
Endocrine resistance
pbg04012
ErbB signaling pathway
pbg04062
Chemokine signaling pathway
pbg04148
Efferocytosis
pbg04151
PI3K-Akt signaling pathway
pbg04360
Axon guidance
pbg04370
VEGF signaling pathway
pbg04510
Focal adhesion
pbg04670
Leukocyte transendothelial migration
pbg04810
Regulation of actin cytoskeleton
pbg04935
Growth hormone synthesis, secretion and action
pbg05100
Bacterial invasion of epithelial cells
pbg05135
Yersinia infection
pbg05146
Amoebiasis
pbg05163
Human cytomegalovirus infection
pbg05165
Human papillomavirus infection
pbg05170
Human immunodeficiency virus 1 infection
pbg05200
Pathways in cancer
pbg05202
Transcriptional misregulation in cancer
pbg05205
Proteoglycans in cancer
pbg05208
Chemical carcinogenesis - reactive oxygen species
pbg05222
Small cell lung cancer
pbg05417
Lipid and atherosclerosis
pbg05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
122495851 (PTK2)
04370 VEGF signaling pathway
122495851 (PTK2)
04151 PI3K-Akt signaling pathway
122495851 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122495851 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122495851 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122495851 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
122495851 (PTK2)
04062 Chemokine signaling pathway
122495851 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
122495851 (PTK2)
09158 Development and regeneration
04360 Axon guidance
122495851 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122495851 (PTK2)
05202 Transcriptional misregulation in cancer
122495851 (PTK2)
05205 Proteoglycans in cancer
122495851 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
122495851 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
122495851 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
122495851 (PTK2)
05163 Human cytomegalovirus infection
122495851 (PTK2)
05165 Human papillomavirus infection
122495851 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
122495851 (PTK2)
05100 Bacterial invasion of epithelial cells
122495851 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
122495851 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122495851 (PTK2)
05418 Fluid shear stress and atherosclerosis
122495851 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
122495851 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122495851 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
pbg01009
]
122495851 (PTK2)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122495851 (PTK2)
Protein kinases [BR:
pbg01001
]
Non-receptor tyrosine kinases
FAK family
122495851 (PTK2)
Protein phosphatases and associated proteins [BR:
pbg01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122495851 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
122495851
NCBI-ProteinID:
XP_043457786
LinkDB
All DBs
Position
F2:complement(80474673..80731537)
Genome browser
AA seq
1155 aa
AA seq
DB search
MLVELAGREAPRPAGAVCMEKSGCGPFPMCWAKDYDRYIAPSKIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCSPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSGIYPDVTHSAARALTWASRSVSSLGALATSPSPLTLLSPCPTSL
LLETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMS
PENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLVGVITENPVWIIMELCT
LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG
DFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF
QGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEE
KVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQ
VSGYPGSHGVTATAGSIYPGQASLLDQTDSWNHRPQEISMWQPNVEDSAALDLRGIGQVL
PTQLVEERLIRQQQEMEEDQRWLEKEERFLVILKPDVRLSRGSIDREDGSLQGPTGNQHI
YQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANL
DRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPA
STHREIEMAQKLLNSDLGELINKMKLAQRCAMTSLQQDHKKQMLTAAHALAVDAKNLLDV
IDQARLRALGHARPR
NT seq
3468 nt
NT seq
+upstream
nt +downstream
nt
atgttggtggaactggcgggccgagaggccccgagaccagcaggtgccgtctgtatggag
aagagcggctgtggtccatttccaatgtgttgggctaaagattatgacagatacatagca
ccaagcaaaataatggcagctgcttaccttgacccaaacttgaatcacaccccgaattca
agtaccaagacccatctgggtaccggagtggaacgttcccccggggcaatggagcgagtg
ttgaaggtctttcattattttgagaacagcagtgagccagccacttgggccagtattatc
aggcacggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgtctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccgactctgaatttcttctatcaacaggtgaaaagtgactacatg
tcggagatagctgaccgggtggaccaggacatcgctttgaagctgggctgcctagaaata
cggcgctcgtattgggagatgcgaggcaacgcgctagagaagaagtccaactatgaggtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaaactgatccagcagacgtttagacagttcgccaacctgaacaga
gaagagagcattctgaaattctttgagatcctctccccagtgtaccgatttgataaagag
tgcttcaagtgtgccctcggttcaagctggattatttcagtggaactggcgatcggccca
gaagaaggaatcagttacctcacggacaagggctgcagccccacacatctggccgacttc
aatcaagtgcagaccattcagtattccaacagcgaagacaaggacaggaaaggaacgctg
cagctgaaaatcgcgggcgcccccgagcctctgacagtgacagcaccgtccctgaccatc
gccgagaatatggctgacctgatagatgggtactgccggctggtgaacggagccacgcag
tcctttatcatcaggccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctccgtatcaggcatctaccct
gacgtcactcacagtgcagccagagccctgacgtgggcttctaggtctgtgtcatcactg
ggagcattggccacctctccctcacccctcactcttttgtcaccctgcccaacctcattg
ctcctcgaaaccgacgactatgctgagattatagacgaagaagatacctacaccatgccc
tcaaaaagctatggaatagacgaagccagggactacgagattcaaagagaaagaatcgag
cttggacggtgcatcggggaaggccagtttggggacgtccaccaaggcgtctacatgagt
ccagagaatccggctttggcggtcgcaattaaaacatgtaaaaactgtacttcggacagc
gtgcgagagaaattccttcaagaagccttaacgatgcgccagtttgaccacccccacatc
gtgaagctggtcggtgtcatcacggagaaccccgtctggataatcatggagctgtgcacg
cttggagagctgaggtcgtttctgcaagtgaggaagtacagtttggatctcgcgtctttg
atcctgtatgcctatcagcttagtacagctctggcgtatctggagagcaaaagattcgtg
cacagggacattgctgctcggaatgttctggtgtcctcaaacgattgcgtaaaattagga
gactttggattatcccggtatatggaagacagtacttactacaaagcttccaaaggaaag
ttgcctattaaatggatggctccagagtccatcaactttcgacgttttacctcagccagt
gacgtgtggatgttcggtgtgtgtatgtgggagatactgatgcatggtgtgaagccgttt
caaggagtgaagaacaatgatgtgatcggtcgaatcgagaacggggagagattaccaatg
cctccaaattgccctcccaccctctacagccttatgacgaaatgctgggcctatgacccc
agcaggcggccccggttcactgagctcaaagctcagctcagcaccatcctggaggaggag
aaggttcagcaagaagaacgaatgaggatggaatcccgaagacaggtcacggtgtcctgg
gactccggagggtccgacgaagcgccacccaagcccagcagacctggttaccccagtcca
cggtccagcgaaggattttatcccagtccccagcacatggtacagaccaatcattaccag
gtgtctggctatcctggctcacatggggtcacagccacggctggcagcatctacccgggt
caggcatctcttttggaccagacggactcatggaatcacagaccacaggagatatcgatg
tggcagcccaacgtggaggactctgcggccctggacctgcgcgggatcgggcaggtgctg
cccacccagctggtggaagagcggctgatccggcagcagcaggaaatggaggaggaccag
cgctggctcgagaaagaggagaggttcctggtcatcctgaaacctgacgtgcggctctct
cgaggcagcatcgacagggaggacgggagtcttcagggcccgacgggaaaccaacacatc
tatcagcctgtgggtaaaccagatcccgcagctccgccaaagaaaccgccgcggcctgga
gcccccggtcacctgggcagccttgccagcctcagcagccccggggacagttacaacgag
ggcgtcaagccatggaggcttcagccccaggaaatcagccccccgcccactgccaacctg
gaccggtccaacgacagggtgtacgagaatgtgacgggcctggtgaaggctgtcatcgaa
atgtccagcaagatccagccagcccccccggaggagtacgttcccatggtgaaggaagtc
ggcctggccctgcggacattactggccaccgtggacgagacccttccggtcctgccagcc
agcactcaccgagagatcgagatggctcagaagctgttgaactccgatctgggcgagctc
atcaacaagatgaagctggcccagcggtgcgccatgaccagcctgcagcaggaccacaag
aagcagatgctgaccgccgcccacgccctggccgtggacgccaagaacttactggacgtc
atcgaccaggccagactgagggcactcggacacgcgaggccgcgctga
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