Paenibacillus polymyxa SC2: PPSC2_16625
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Entry
PPSC2_16625 CDS
T01335
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ppm
Paenibacillus polymyxa SC2
Pathway
ppm00300
Lysine biosynthesis
ppm00550
Peptidoglycan biosynthesis
ppm01100
Metabolic pathways
ppm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ppm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PPSC2_16625 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PPSC2_16625 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PPSC2_16625 (murF)
Enzymes [BR:
ppm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PPSC2_16625 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
APOBEC4_like
Motif
Other DBs
NCBI-ProteinID:
ADO57508
UniProt:
E3E8F9
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All DBs
Position
complement(3759345..3760748)
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AA seq
467 aa
AA seq
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MKRTIGQIASMCGGTLHAEADAERMVEGVFTDSRRPQSLGLFVPLVGERFDGHHYVQQIV
SERGATAYLWQKDHGAPPTVNAIEVEDTLEALQHLAAAYLRETGVSVVGITGSNGKTTTK
DIVNALLGTTFKVHKTEGNYNNHIGLPLTVLSMPQDTDILVLEMGMSGRGEIRLLANIAQ
PDVAVITNIGESHLLQLGSRTEIARAKLEIASGIKPGGLLIYNGDEPLLPQVLAEPETVK
PEGLELFTFGLAADNDDYPTEITSDGEGSLFITAQSGQEAFRLPLLGQHNVVNGLAALAV
ARHFNVDADHIRKGLSSLKLTGMRIEVVKCSDGLTVLNDAYNASPASMKAAIQTLSAYKT
GGRKIAVLGDMLELGAEEKQFHEEIGRFAAKHNIEALFTYGALGASIAQGAQGTMPTANV
HAYTDKQKLIQHLRSYLHADDIVLVKASRGMRLEEIVDALKNGPLQN
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgaaaagaacaatcggtcagattgcatccatgtgtggaggaacacttcacgcagaggcg
gacgccgaacggatggttgagggcgtttttacagactcacgcaggccgcagagtctggga
ctgttcgttccactcgtgggtgaacgatttgatggacatcattatgttcagcagatcgta
agcgagagaggggcaacagcatatttatggcaaaaggatcatggagcacctccgactgtc
aatgctattgaggtcgaggatacgttagaagctcttcagcatctagcagctgcatacttg
cgcgaaactggcgtttctgtcgttggaatcacgggaagcaacggcaagacgacgacaaaa
gatattgtaaatgctctattaggcacgacttttaaagtacacaaaaccgaagggaattat
aacaatcatatcgggttgcctttaacagtactgtccatgccgcaggatacagatatcctg
gttctggagatgggcatgagtggacgcggggaaatccgtctgctggctaatattgcccaa
ccagatgtagctgtcataactaacattggcgaatcgcatttacttcagcttggttctcgc
actgaaattgctcgtgcaaagctggaaatcgcaagtgggattaaacccggtggattgctt
atctataatggggatgaaccactacttccacaagtgttggcggagcctgaaacggtcaag
cctgaaggattagaattattcacgttcgggttagctgcggacaatgatgattatccaact
gaaatcacttcggatggagaaggtagcttattcataacagcccaatcaggccaagaggct
ttccggcttcccttgctcggacagcacaatgttgtaaacggattggcagcgctggcggta
gcacgtcatttcaatgtggatgcagaccatatacgtaaagggttgtcgtctttaaagctg
acgggcatgcgcattgaggtcgtgaagtgttcggatggacttaccgtgctaaatgacgct
tacaatgccagtcctgcttcaatgaaggctgcaattcagacgttgtctgcatataaaacg
ggtggacgtaaaatagccgtgcttggtgatatgctggagctgggcgctgaggaaaagcaa
tttcatgaagaaattgggcgttttgctgcaaagcataacatagaggcactgtttacctat
ggtgcattaggcgcttcgattgcgcagggtgcgcaagggacaatgccaactgctaacgta
catgcttatacagataagcaaaagctgatccagcatttgcggtcttatctccatgccgat
gatattgtgctggttaaggcatccagagggatgcgattagaagaaattgtggatgcgctg
aaaaacggtccgctacagaactga
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