Streptococcus mutans GS-5 (serotype c): SMUGS5_02650
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Entry
SMUGS5_02650 CDS
T02185
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
smut
Streptococcus mutans GS-5 (serotype c)
Pathway
smut00300
Lysine biosynthesis
smut00550
Peptidoglycan biosynthesis
smut01100
Metabolic pathways
smut01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
smut00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMUGS5_02650
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMUGS5_02650
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMUGS5_02650
Enzymes [BR:
smut01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMUGS5_02650
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AFM81055
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Position
551267..552625
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AA seq
452 aa
AA seq
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MKLTLQEIASVVGAQNDVSLFEDLTINAIEFDSRQIKTGDLFLPLQGARDGHEFIDTAFA
NGAVATFSEKNITSDYPYILVVDCLKAFQDLAQYYLEKMRVDVIAVTGSNGKTTTKDMIA
TILATTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHLGDIAFLSNLTHPHIA
VVTLIGEAHLEFFGSREKIAEGKMQITQGMDGHGILIAPADKIINSFLPEKQKVIRFGAD
EDIFVTELEEHKNYLNFKTNFLDNEIKLPVTGKYNATNAMIASYVGKLLNVSEEKIISAL
AQLNLTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSSIPANNGGKKIAVLADMKE
LGDSELALHAAMIASLDPAVIDRIFLFGPLMQALADEVAQVYSVGKWYYFAQVDQVDELT
EQIQKVLGPNDQILLKGSNSMKLAQVVECLEG
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgaagttaactttacaagagatagcctcggttgtaggtgctcaaaatgatgtcagtctt
tttgaagatcttaccatcaatgctattgaatttgacagccgccagataaagacaggtgat
ttatttttacctttgcagggtgcgcgtgatggccatgagtttattgatactgcttttgcc
aatggtgctgttgctactttttccgaaaaaaacataaccagtgattatccctatatttta
gttgtagattgcttgaaagcttttcaggatttggcgcaatactatttggagaaaatgcgg
gttgatgttattgctgtaacaggctctaatggaaaaacaaccacaaaggacatgatagca
actattttagcaactacttacaagacttacaagacacaaggtaattataataatgaaatc
ggtctgccttatacagttttacacatgcctgatgatactgaaaaaattgtacttgaaatg
ggtcaggaccatctcggtgatattgcctttctgtctaatcttacccatcctcacatagct
gttgtcaccttgattggtgaagctcatttagagttctttggcagccgtgagaaaattgct
gaaggaaaaatgcaaattactcaaggaatggatggtcatgggattcttattgcaccagcg
gataaaatcattaattcatttttaccagaaaagcaaaaggttattcgctttggagctgat
gaagatatttttgtgaccgaattagaagagcataaaaactatttgaactttaaaacgaat
ttcctagataatgagattaaattgccagtaactggtaaatataatgctactaatgctatg
attgctagctatgttggaaaactgcttaatgtctctgaagaaaagattatctctgcactg
gctcagctcaatctaactcgtaatcgaacggaatggaaaaaagcggctaacggtgcagat
atcttatctgatgtttataatgctaatccaacagctatgaaactgattttggagactttc
tccagcattccagcaaataatggtggtaaaaaaattgcggtgctggcagatatgaaagaa
ttaggagacagtgaattagccttacatgcagccatgattgctagtctagatcctgcagtg
atagatcgtatttttctttttggaccactaatgcaagctctagcagatgaagtcgcccaa
gtttattcagtagggaaatggtattattttgcccaagttgatcaggtagatgagctcact
gagcaaattcaaaaggtattaggccctaatgaccaaatacttctaaagggatcaaattcc
atgaaattggcccaagttgtggagtgtttggaagggtaa
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