Streptococcus pyogenes MGAS15252 (serotype M59): MGAS15252_1096
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Entry
MGAS15252_1096 CDS
T01794
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase protein MurF
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stg
Streptococcus pyogenes MGAS15252 (serotype M59)
Pathway
stg00550
Peptidoglycan biosynthesis
stg01100
Metabolic pathways
stg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
MGAS15252_1096 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MGAS15252_1096 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MGAS15252_1096 (murF)
Enzymes [BR:
stg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
MGAS15252_1096 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4419
Motif
Other DBs
NCBI-ProteinID:
AFC66433
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Position
complement(1090803..1092194)
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AA seq
463 aa
AA seq
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MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRDGHEFIDLAFQ
NGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHMGDIRLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGNQQ
EIDVTGIQEDKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVTDEDIIAALQ
TVTLTGNRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GKDSVILHSQLIDSLTSGNIDQLVFYGDHIKELARLASQVYPAEQVHYFLKTEQEDQFEA
MAQYVQNILNPFDQILLKGSHSMSLEKLVDRLVTDKNCDSYQP
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaaccttacacgaagtggctaaaatagttgacgcccaaaataatgtgtctgac
ttagacgacgttcctctgcatcacattgaatttgatagccgaaagattacaaaaggagac
ctctttttacccttaaaaggtcaaagggatggtcatgagtttattgatttagcctttcaa
aatggagctgtcgctactttttcagaaaaagaattgccggggaaacctcaccttcttgtt
gaagactgcctaaaagcttttcaaaagctagcccattattatattgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggtaaaacttccaccaaagatatgataggagct
gtcctatcaaccacttacaaaacttacaaaacgcaaggaaattacaataatgagattggt
ttgccttacaccgttctccacatgcctgacgatacggaaaaaattgttcttgaaatggga
caagatcacatgggagatattcgtcttctgtctgaaattgcaaggcctcgtattgcagtt
ttaaccttagtcggcgaagctcatttagaatattttggaagccgagacaaaatagcccaa
ggcaaaatgcagattgttgacggcatgaattcagatgggattttaattgctccgggagat
ccgattattgacccatatcttccagaaaatcagatggttatccgttttggaaatcagcag
gaaattgacgttactggtattcaagaagacaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgtaggaaaactattggcagtaacagacgaggatattatagctgctttacag
actgtgacgttgacaggtaatcgtacggagtggaaaaaagcagccaatggtgctgatatt
ttatcagatgtctacaatgccaacccaacagccatgcgtctgattttagaaacatttgct
aacatagcaaagaaccccggaggaaaaaagattgcagtgctagcagatatgaaagaactt
ggaaaggattcagtgatacttcattctcagttaattgacagcttaacatcaggtaatatt
gatcagcttgttttttatggggatcatattaaagaattagcacggttggcaagtcaggtt
tatcctgctgagcaagtacattattttttaaaaactgaacaagaagaccagtttgaagcc
atggcacaatatgttcaaaacattcttaatccctttgatcaaattcttttaaaaggcagc
cactcgatgtcgctagaaaagttagtagatcgattagtgactgacaagaattgtgacagc
tatcagccttga
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