Ursus arctos horribilis (North American brown bear): 113269779
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Entry
113269779 CDS
T05909
Symbol
PTCH1
Name
(RefSeq) protein patched homolog 1 isoform X1
KO
K06225
patched 1
Organism
uah
Ursus arctos horribilis (North American brown bear)
Pathway
uah04024
cAMP signaling pathway
uah04340
Hedgehog signaling pathway
uah04360
Axon guidance
uah05200
Pathways in cancer
uah05205
Proteoglycans in cancer
uah05217
Basal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
113269779 (PTCH1)
04024 cAMP signaling pathway
113269779 (PTCH1)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
113269779 (PTCH1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113269779 (PTCH1)
05205 Proteoglycans in cancer
113269779 (PTCH1)
09162 Cancer: specific types
05217 Basal cell carcinoma
113269779 (PTCH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Patched
Sterol-sensing
Motif
Other DBs
NCBI-GeneID:
113269779
NCBI-ProteinID:
XP_026374485
LinkDB
All DBs
Position
Unknown
AA seq
1451 aa
AA seq
DB search
MASAGNAAEPQDRGGGGSCSGAPGRPAGGGRRRRTGGLRRNAVLDRDYLHRPSYCDAAFA
LEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANL
ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALRQHLDS
ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
QSGTAYLLGKPPLQWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
PDCPATAPNKNATKPLDVALVLSGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVTPNSTQQVLS
FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
RREDRRLDIFCCFTSPCVSRVIQVEPQAYTETHDNTRYSPPPPYSSHSFAHETQITMQST
VQLRTEYDPHTHVYYTTAEPRSEISVQPVTMTQDTLSCQSPESTSSTRDLLSQFSDSSLH
CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHKSFSNVKYVMLEENKQLP
KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
LTKRRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICNNYTSLGLSSYPNGYPFLFWEQY
IGLRHWLLLSISVVLACTFLVCAVFLLNPWTAGIIVTVLALMTIELFGMMGLIGIKLSAV
PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
PSVVRFAVPPGHANNGSDSSDSEYSSQTTVSGISEELRHYEAQQGTGGPAHQVIVEATEN
PVFARSTVVHPEARHHPPSNPRQQPPPDSESLPPGRPGQQPRREPPREGLRPPPYRPRRD
AFEISTDGHSGPSNRDRAGPRGARSNNPRHPAFTAMGSSAPSYCQPITTVTASASVTVAV
HPPPAPGPSSAWNPRGGLCPGYGDYPETDHGLFEDPHVPFNVRCERRDSKVEVIELQDVE
CEERPRGGSSN
NT seq
4356 nt
NT seq
+upstream
nt +downstream
nt
atggcctcggctggtaacgccgccgagccccaggaccgcggcggcggcggcagctgcagc
ggggccccgggccggccggccggcggcgggaggcgcagacggaccggggggctgcgccgc
aacgccgtgctggaccgggactatctgcaccggcccagctactgcgacgccgccttcgct
ctggagcagatttccaaggggaaagctactggccggaaagcgccgctgtggctgagagcg
aagtttcagagactcttatttaaactgggttgttacattcaaaaaaactgcggcaagttc
ttggttgtgggcctcctcatatttggggccttcgctgtgggattaaaggcagctaatctc
gagaccaacgtggaggagctgtgggtggaagttggtggacgagtaagtcgtgaattaaat
tatactcgccagaagattggagaagaggctatgtttaatcctcaactcatgattcagacc
ccaaaagaagaaggtgctaacgtcttgaccacggaagctctccgacaacacctggactca
gcgctccaggccagccgagtccatgtatatatgtataacaggcagtggaaattggaacat
ttgtgttacaaatccggagaacttatcacagaaacaggttacatggatcagataatagaa
tatctttacccttgtttaattattacgcctttggactgcttctgggaaggggcaaagtta
cagtctgggacagcatacctactaggtaagcctcctttgcagtggacaaactttgaccct
ttggaattcctggaagagttaaagaaaataaactatcaagtggacagctgggaggaaatg
ctgaataaggccgaagttggtcatggttacatggaccggccctgcctcaacccggctgat
ccagactgccccgccacagcccccaacaaaaacgcaaccaaacctcttgatgtggccctt
gttttgagtggtggatgccatggattatccagaaagtatatgcactggcaggaggagctg
attgtgggtggcacggtcaagaacagcactgggaagctggtcagtgcccacgccctgcag
accatgtttcagttaatgacgcccaagcaaatgtacgagcacttcaaggggtacgagtat
gtctcacacatcaactggaacgaggacaaggcagcagccatcctggaggcctggcagagg
acgtacgtggaggtggttcatcaaagtgtcactccgaactccactcagcaggtgctttcc
tttaccacgacgaccctggacgacatcctgaagtccttctccgatgtcagtgtcatccga
gtggccagcggctacctactgatgcttgcctatgcctgtttaaccatgctgcgctgggac
tgctccaagtcccagggtgccgtggggctggctggcgtcctgttggttgcactgtcagtg
gctgcaggattgggcctgtgctcattgatcgggatttcctttaacgctgcaacaactcag
gttttgccgtttcttgctcttggcgttggtgtggacgatgttttccttctggcacatgca
tttagtgagacaggacagaataaaagaatcccttttgaggacaggactggagaatgcctc
aagcgtacgggagccagtgtggccctcacgtccatcagcaatgtcacagccttctttatg
gccgcactgatccccattcccgccctgcgagccttctccctccaggcggctgtcgtagtg
gtattcaattttgctatggttctgctcatttttcctgcgattctcagcatggatttgtat
cgacgtgaggacaggagattggatattttctgctgttttacaagcccctgcgtcagcaga
gtgattcaggtcgaacctcaggcctacacggagactcacgataacacccgctacagcccc
ccacccccctacagcagccacagcttcgcccatgaaacccagatcaccatgcagtccaca
gtgcagctccgcacagagtacgacccccacacgcacgtgtactacaccactgctgagccg
cgctccgagatctctgtgcagcccgtcaccatgacccaggataccctcagctgccagagc
ccagaaagcaccagctccacgagggacctgctctcccagttctccgactccagcctccac
tgccttgagcccccttgcaccaagtggacactttcatcttttgctgagaaacactatgct
cctttcctcttgaaaccaaaagccaaggtcgtggtgatcttccttttcctgggcttgctg
ggggtcagcctttatgggaccacccgagtgcgcgatgggctggaccttacggacattgtg
cctcgggaaaccagagaatatgactttattgctgcacaattcaaatacttttctttctac
aacatgtatatagtcacccagaaagcagactacccaaatatccagcacttactttacgac
cttcacaagagtttcagcaatgtgaagtatgtcatgttggaagaaaataaacagcttccc
aaaatgtggctgcactacttcagagactggctccaaggacttcaggatgcatttgacagt
gactgggaaactgggaaaatcatgccaaacaattacaaaaatggatcagatgacggggtc
cttgcctacaaactcctggtgcaaactggcagccgtgataaacccatcgacatcagtcag
ttgaccaaacggcgcctggtggacgcagatggcatcatcaatcccagcgcgttctacatc
tacctgacggcgtgggtcagcaatgaccctgtggcttacgccgcctcccaggccaacatc
cggcctcaccgtcctgagtgggtgcacgacaaagctgactacatgccagaaaccaggctc
agaatccccgcagcagagcccatcgagtacgcgcagttccctttctacctcaacggtttg
cgggacacctcagacttcgtggaagccatcgagaaggtcagaaccatctgcaacaactac
acgagcctcgggctgtccagctaccccaacggctaccccttcctcttctgggagcagtac
atcggccttcgccactggctcctgctgtccatcagtgtggtgctggcctgcacgttcctg
gtgtgtgcagtcttcctcctgaacccctggacggccgggatcattgtgacggtgctggct
ttgatgacgatcgagctcttcggcatgatgggcctcattggaatcaagctgagtgccgtg
cccgtggtcatcctcatcgcttccgtcggcataggagtggaattcaccgtgcacgtggct
ctggcctttctaacggccattggcgataagaaccgcagggccgtgctcgccctggagcac
atgtttgcacccgtcctggacggcgccgtttccactctgctgggagtgctgatgcttgca
ggatctgagtttgatttcattgtcaggtatttctttgctgtcctggcaatcctgacaatc
ctgggcgttctcaacgggctggttttgctcccagtccttctgtccttcttcggaccgtac
cccgaggtgtctccagccaacgggctgaaccgactgcccaccccttcccctgagccgccc
cccagtgtggtccggtttgccgtgccccccggtcatgcaaacaatgggtcggattcctct
gactcagagtacagttctcagacgacagtgtcaggcatcagcgaagagcttcggcactat
gaggcccagcagggcaccgggggccctgcccaccaagtgatcgtggaagccacagaaaac
cctgtctttgcccgctccactgtggtccatcccgaagcgagacatcaccccccctcaaac
cctcgacagcagccccccccggactcagagtccctgcctcccggacgaccaggccagcag
ccccggagggaaccccccagagaaggcttgcggccacccccctacagaccgcgcagagac
gctttcgaaatttctactgacgggcattctggccctagcaatagggaccgtgcgggcccc
cggggagcccgttctaacaaccctcggcacccagcgttcactgccatgggcagctccgca
cccagctactgccagcccatcaccactgtgacggcctcggcgtccgtgactgttgcagta
caccccccgcctgcccccgggcccagctccgcgtggaacccccgagggggcctgtgcccg
ggctacggggactaccccgagactgaccacgggctgtttgaggacccccacgtgcctttt
aacgtgcggtgcgagaggagggattccaaggtggaagtcatagagctgcaggacgtggaa
tgtgaggagaggccccggggcggcagctccaactga
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