Yersinia enterocolitica subsp. enterocolitica 8081 (serotype 0 8): YE0668
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Entry
YE0668 CDS
T00469
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diami nopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
yen
Yersinia enterocolitica subsp. enterocolitica 8081 (serotype 0:8)
Pathway
yen00300
Lysine biosynthesis
yen00550
Peptidoglycan biosynthesis
yen01100
Metabolic pathways
yen01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
yen00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
YE0668 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
YE0668 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
YE0668 (murF)
Enzymes [BR:
yen01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
YE0668 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
CAL10777
UniProt:
A1JJI9
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Position
771737..773101
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AA seq
454 aa
AA seq
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MIKVSLHFLSTLLNAEYIGRDSADITEVTIDTRKVTPGCLFVALKGERFDGHDFAEDAVA
AGAGALLVSKHLLVAAPQLVVKDTRLALGQLAAWVRQQVPARVVALTGSSGKTSVKEMVA
AILRQCGKVLYTAGNFNNDIGVPLTLLRLTPEYDFAVIELGANHIGEIAYTTDLSRPESA
LVNNLAAAHLEGFGSLAGVAQAKGEIFAGLPANGTAIINADSNDWPHWQETLHNKRVWRF
APLGAEDIDFFASDVRITPQVTHFTLHSPFGTVGIELPLPGRHNIANALAAAALAMSVGA
SLAAVREGLTQLPAVPGRLFPIELAAGKLLLDDSYNANVGSMTAAAQVLAEMPGYRVMVV
GDMGELGETAVDCHRQVGEAAQQAGIDKVLSVGTLSQTLSDASGCGEHFQDKNTLAARVS
ELLLEHPVITVLIKGSRSAAMENVVRALQEKASC
NT seq
1365 nt
NT seq
+upstream
nt +downstream
nt
atgattaaggtctcgctgcattttctgtccacactgctgaacgctgaatatattggtcgc
gatagcgccgatattaccgaagtgaccattgatacccgtaaggtcactcctgggtgttta
ttcgtggcgctgaaaggcgagcgttttgatggacatgactttgcagaagatgctgttgcc
gctggcgctggtgctttgctggtaagtaaacacttactggtggcggcaccacaattagtg
gttaaagacacccgcctggcattggggcaattggctgcatgggtgcgccagcaagtgcct
gcccgtgtggtagccttgaccggttcctccggtaaaacctcagtaaaagaaatggttgcg
gcaattttgcgccaatgtggcaaggtgctttataccgccggtaactttaataatgatatc
ggcgtaccgctgaccttgctgcgtctgacgcccgagtatgattttgctgtcattgagcta
ggtgcaaaccatatcggtgaaattgcctacaccacggacttaagccgccctgaaagtgct
ttggttaacaatttagctgccgcacatttggaaggttttggctcactggctggagtggct
caagccaaaggcgagattttcgccggcttacccgcgaatggcacagcgattattaatgct
gatagcaatgactggccgcactggcaggaaacgttacataacaagcgcgtatggcgtttt
gcacctctcggcgcagaagatatcgatttctttgccagtgacgtgcgtattacaccacaa
gtcactcatttcactctgcattctcccttcggcacggtgggtatcgaattgccgctgccg
gggcgacataacattgccaatgcattagccgccgcggcgttagccatgtcggtcggcgct
agtttagctgccgttcgtgaggggctgacgcaattaccggccgtaccaggtcgcttattc
ccgattgaacttgctgctggcaagttgctgctcgatgacagctacaacgccaatgtcggc
tccatgaccgccgccgcgcaagtactggctgaaatgccgggctaccgagtgatggtggtg
ggtgatatgggcgagttgggtgaaaccgcagtcgattgtcaccgtcaggtgggtgaagcc
gcgcaacaggcgggcatcgataaagtccttagcgtaggtacattaagccagacacttagc
gatgcaagcgggtgcggcgaacattttcaggataagaacactttggcagcccgtgtcagt
gaattgctgctcgaacatccggttatcaccgttttaattaaaggttcacgtagcgccgcc
atggaaaatgtcgtgcgtgcgttacaggagaaggcatcatgttag
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