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Entry	Name	Description	Category	Pathway	Gene
H00003	Acute myeloid leukemia	... upregulation of cell survival genes. The most common of these activating events were observed in the RTK Flt3, in N-Ras and K-Ras, in Kit, and sporadically in other RTKs. Alterations in myeloid transcription ...	Cancer	hsa05221 Acute myeloid leukemia	PML-RARalpha (translocation) [HSA:5371] [KO:K10054] AML1-ETO (translocation) [HSA:861] [KO:K08367] PLZF-RARalpha (translocation) [HSA:7704] [KO:K10055] FLT3 [HSA:2322] [KO:K05092] KIT [HSA:3815] [KO:K05091] NRAS [HSA:4893] [KO:K07828] KRAS [HSA:3845] [KO:K07827] AML1 [HSA:861] [KO:K08367] CEBPA [HSA:1050] [KO:K09055] CBFB [HSA:865] [KO:K25826] CHIC2 [HSA:26511] DNMT3A [HSA:1788] [KO:K17398] ETV6 [HSA:2120] [KO:K03211] GATA2 [HSA:2624] [KO:K17894] JAK2 [HSA:3717] [KO:K04447] LPP [HSA:4026] [KO:K16676] MLLT10 [HSA:8028] [KO:K23588] NPM1 [HSA:4869] [KO:K11276] NUP214 [HSA:8021] [KO:K14317] PICALM [HSA:8301] [KO:K20044] SH3GL1 [HSA:6455] [KO:K11247] TERT [HSA:7015] [KO:K11126]
H02411	Chronic myelomonocytic leukemia	Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder associated with peripheral blood monocytosis, with an inherent risk for leukemic transformation. CMML has overlapping ...	Cancer		TET2 (mutation) [HSA:54790] [KO:K24309] ASXL1 (mutation) [HSA:171023] [KO:K11471] SRSF2 (mutation) [HSA:6427] [KO:K12891] NRAS (mutation) [HSA:4893] [KO:K07828] KRAS (mutation) [HSA:3845] [KO:K07827] CBL (mutation) [HSA:867] [KO:K04707] RUNX1 (mutation) [HSA:861] [KO:K08367] SF3B1 (mutation) [HSA:23451] [KO:K12828] ZRSR2 (mutation) [HSA:8233] [KO:K24273] U2AF1 (mutation) [HSA:7307] [KO:K12836] DNMT3A (mutation) [HSA:1788] [KO:K17398] EZH2 (mutation) [HSA:2146] [KO:K11430] TP53 (mutation) [HSA:7157] [KO:K04451] NPM1 (mutation) [HSA:4869] [KO:K11276] JAK2 (mutation) [HSA:3717] [KO:K04447] FLT3 (mutation) [HSA:2322] [KO:K05092]
H02412	Atypical chronic myeloid leukemia	Atypical chronic myeloid leukemia (aCML) is a rare subtype of myelodysplastic/myeloproliferative neoplasm (MDS/MPN). It is characterized by leukocytosis, granulocytic dysplasia, and typically poor patient ...	Cancer		SETBP1 (mutation) [HSA:26040] [KO:K23217] NRAS (mutation) [HSA:4893] [KO:K07828] KRAS (mutation) [HSA:3845] [KO:K07827] JAK2 (mutation) [HSA:3717] [KO:K04447] CSF3R (mutation) [HSA:1441] [KO:K05061] ASXL1 (mutation) [HSA:171023] [KO:K11471] ETNK1 (mutation) [HSA:55500] [KO:K00894] TET2 (mutation) [HSA:54790] [KO:K24309] SRSF2 (mutation) [HSA:6427] [KO:K12891] EZH2 (mutation) [HSA:2146] [KO:K11430] RUNX1 (mutation) [HSA:861] [KO:K08367] CBL (mutation) [HSA:867] [KO:K04707] FLT3 (mutation) [HSA:2322] [KO:K05092] CEBPA (mutation) [HSA:1050] [KO:K09055] IDH2 (mutation) [HSA:3418] [KO:K00031]

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