KEGG   ENZYME: 2.5.1.20
Entry
EC 2.5.1.20                 Enzyme                                 
Name
rubber cis-polyprenylcistransferase;
rubber allyltransferase;
rubber transferase;
isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase;
cis-prenyl transferase;
rubber polymerase;
rubber prenyltransferase
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
Sysname
polycis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase
Reaction(IUBMB)
polycis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a polycis-polyprenyl diphosphate longer by one C5 unit [RN:R08400]
Reaction(KEGG)
R08400;
(other) R03917
Substrate
polycis-polyprenyl diphosphate;
isopentenyl diphosphate [CPD:C00129]
Product
diphosphate [CPD:C00013];
polycis-polyprenyl diphosphate longer by one C5 unit
Comment
Rubber particles act as acceptor.
History
EC 2.5.1.20 created 1976
Pathway
ec00900  Terpenoid backbone biosynthesis
Reference
1
  Authors
Archer BL, Cockbain EG.
  Title
Rubber transferase from Hevea brasiliensis latex.
  Journal
Methods Enzymol 15:476-480 (1969)
Reference
2  [PMID:16742418]
  Authors
McMullen AI, McSweeney GP.
  Title
The biosynthesis of rubber: Incorporation of isopentenyl pyrophosphate into purified rubber particles by a soluble latex serum enzyme.
  Journal
Biochem J 101:42-47 (1966)
DOI:10.1042/bj1010042
Other DBs
ExplorEnz - The Enzyme Database: 2.5.1.20
IUBMB Enzyme Nomenclature: 2.5.1.20
ExPASy - ENZYME nomenclature database: 2.5.1.20
BRENDA, the Enzyme Database: 2.5.1.20
CAS: 62213-41-6
LinkDB

KEGG   REACTION: R03917
Entry
R03917                      Reaction                               
Name
poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase
Definition
n Isopentenyl diphosphate <=> cis-1,4-Polyisoprene + n Diphosphate
Equation
n C00129 <=> C02321 + n C00013
Comment
see R08400
Enzyme
2.5.1.20
Pathway
rn00900  Terpenoid backbone biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.20
     R03917  n Isopentenyl diphosphate <=> cis-1,4-Polyisoprene + n Diphosphate
LinkDB

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