KEGG ORTHOLOGY: K10249

ORTHOLOGY: K10249

Entry

K10249 KO

Name

ELOVL4

Definition

elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]

Pathway

ko00062

Fatty acid elongation

ko01040

Biosynthesis of unsaturated fatty acids

ko01100

Metabolic pathways

ko01110

Biosynthesis of secondary metabolites

ko01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Disease

H00819

Stargardt disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10249  ELOVL4; elongation of very long chain fatty acids protein 4
   01040 Biosynthesis of unsaturated fatty acids
    K10249  ELOVL4; elongation of very long chain fatty acids protein 4
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10249  ELOVL4; elongation of very long chain fatty acids protein 4
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10249  ELOVL4; elongation of very long chain fatty acids protein 4
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10249  ELOVL4; elongation of very long chain fatty acids protein 4

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	6785(ELOVL4)

PTR:	462842(ELOVL4)

PPS:	100968249(ELOVL4)

GGO:	101129175(ELOVL4)

PON:	100440564(ELOVL4)

NLE:	100596130(ELOVL4)

MCC:	692070(ELOVL4)

MCF:	102138130(ELOVL4)

CSAB:

103239978(ELOVL4)

RRO:	104682056(ELOVL4)

RBB:	108512609(ELOVL4)

CJC:	100396385(ELOVL4)

SBQ:	101034271(ELOVL4)

MMU:	83603(Elovl4)

MCAL:

110302312(Elovl4)

MPAH:

110328059(Elovl4)

RNO:	315851(Elovl4)

MUN:	110546457(Elovl4)

CGE:	100774858(Elovl4)

NGI:	103729172(Elovl4)

HGL:	101701805(Elovl4)

CCAN:

109698009(Elovl4)

OCU:	100353429(ELOVL4)

TUP:	102475313(ELOVL4) 102489276

CFA:	481894(ELOVL4)

VVP:	112926381(ELOVL4)

AML:	100475550(ELOVL4)

UMR:	103657419(ELOVL4)

UAH:	113261082(ELOVL4)

ORO:	101379613(ELOVL4)

FCA:	101101313(ELOVL4)

PTG:	102960657(ELOVL4)

AJU:	106976574(ELOVL4)

BTA:	532015(ELOVL4)

BOM:	102284782(ELOVL4)

BIU:	109558607 109563726(ELOVL4)

BBUB:

102398668(ELOVL4) 102414871

PHD:	102340925(ELOVL4)

CHX:	102172444(ELOVL4) 106502144

OAS:	101113417(ELOVL4) 105608607

SSC:	100511670(ELOVL4)

CFR:	102512198(ELOVL4)

CDK:	105104040(ELOVL4)

BACU:

102998571 103011283(ELOVL4)

LVE:	103083406(ELOVL4)

OOR:	101283409(ELOVL4)

DLE:	111183214(ELOVL4)

ECB:	100069512(ELOVL4)

EPZ:	103548486(ELOVL4)

EAI:	106842949(ELOVL4)

MYB:	102256207(ELOVL4)

MYD:	102756238(ELOVL4)

MNA:	107532845(ELOVL4)

HAI:	109387807(ELOVL4)

RSS:	109446292(ELOVL4)

DRO:	112319333(ELOVL4)

PALE:

102897900(ELOVL4)

LAV:	100654940(ELOVL4)

TMU:

101360177

MDO:	100017828(ELOVL4)

SHR:	100928562(ELOVL4)

PCW:	110200297(ELOVL4)

OAA:	100081381(ELOVL4)

GGA:	421850(ELOVL4)

MGP:	100546793(ELOVL4)

CJO:	107312020(ELOVL4)

APLA:

101790547(ELOVL4) 101801566

ACYG:

106048591(ELOVL4)

TGU:	100225997(ELOVL4) 100232706

LSR:	110475714 110476538(ELOVL4)

SCAN:

103819554 103822499(ELOVL4)

GFR:	102040968 102044122(ELOVL4)

FAB:	101819154(ELOVL4) 101819804

PHI:	102102223 102114272(ELOVL4)

PMAJ:

107202280(ELOVL4) 107205111

CCAE:

111923378 111925784(ELOVL4)

CCW:	104692774(ELOVL4) 104696121

ETL:	114066535 114067169(ELOVL4)

FPG:	101919974(ELOVL4) 101921045

FCH:	102052860 102056363(ELOVL4)

CLV:	102095164 102097944(ELOVL4)

EGZ:	104124213 104132758(ELOVL4)

NNI:	104021788 104022023(ELOVL4)

ACUN:

113477647(ELOVL4)

AAM:	106488771 106489580(ELOVL4)

ASN:	102373426(ELOVL4)

AMJ:	102573512(ELOVL4)

PSS:	102446236(ELOVL4) 102463304

CMY:	102932502 102939512(ELOVL4)

CPIC:

101936216 101945122(ELOVL4)

ACS:	100558520(elovl4)

PVT:	110085734(ELOVL4) 110091506

PBI:	103053806(ELOVL4)

PMUR:

107288224(ELOVL4)

GJA:	107121888(ELOVL4)

XLA:	108717990 734428

XTR:	100496222(elovl4) 101732387 101733189

NPR:	108798588(ELOVL4) 108799010

DRE:	335732(elovl4b) 393769(elovl4a) 554145(elovl8b)

SRX:	107713923 107714853 107714912 107726252 107729115 107736802 107743843 107750984 107751851

SANH:

107657928 107657936 107664178 107679337 107688984 107689158 107689169 107697898 107699894

SGH:	107558740 107559048 107578807 107585829 107599298 107602526

CCAR:

109056939 109057708 109074280 109078047 109083719 109098404 109104065

IPU:	108265939 108272628(elovl4) 108275555(ELOVL4)

PHYP:

113527000(elovl4) 113530681 113534933

AMEX:

103026255 103035050(elovl4) 103039014

EEE:	113572917(elovl4)

TRU:	101065200 101072132(elovl4) 101075102

TNG:	GSTEN00002942G001 GSTEN00020209G001 GSTEN00020666G001

LCO:	104918438 104925635(elovl4) 104926213

NCC:	104949334(elovl4) 104954092 104955464 104955465 104959623 104965520 104965521

MZE:	101477514 101479286 101481327 101483690 112431397 112431742 112432417 112433077 112433434 112433435 112434435 112434813 112434814 112436132 112436141

OLA:	101158407 101161285 101165545 101168572

XMA:	102217542 102220842 102231820 102235415

XCO:	114142270 114146238 114151186 114158200

PRET:

103457721 103463607 103478339 103479188

NFU:	107378026(elovl4) 107378783 107393252 107393253 107393254

KMR:	108231727 108232315

CSEM:

103380776(elovl4) 103388604 103393619

LCF:	108877346 108883232 108888589 108893054 108896792(elovl4)

SDU:	111227693 111232162 111239138 111239212

HCQ:	109515526 109527839 109531419 109532073 109532074

BPEC:

110166812 110167734 110167755 110170367 110171410

MALB:

109952214 109958170 109964009

SASA:

100500788(elovl4) 106564638 106569295 106571493 106574012 106597446 106597646 106606161 106613536

OTW:	112217684 112241697 112246732 112250406 112250645 112252037 112261107

SALP:

111952983 111954525 111956896 111973471

ELS:	105017639(elovl4) 105023511 106023669

SFM:	108929205 108935055 108937440(elovl4)

PKI:	111844578 111851539

LCM:	102346876 102364316(ELOVL4)

CMK:	103181830 103182793 103186183(elovl4)

BFO:	BRAFLDRAFT_129515 BRAFLDRAFT_236049 BRAFLDRAFT_236052

CIN:	100176701 100182495 619277(elo)

SPU:	588063 593296

APLC:

110987689 110987690 110991136

SKO:	100373013 100375515 100377822

DME:	Dmel_CG11801(Elo68beta) Dmel_CG17821(CG17821) Dmel_CG18609(CG18609) Dmel_CG32072(Elo68alpha)

DPO:	Dpse_GA15013 Dpse_GA23552

DAN:	Dana_GF10549 Dana_GF13758

DER:	6543867 6543868 6547301 6547302

DPE:	6591184 6596053

DSE:	Dsec_GM19879 Dsec_GM19880 Dsec_GM24775 Dsec_GM24776

DSI:	Dsimw501_GD12826(Dsim_GD12826) Dsimw501_GD12827(Dsim_GD12827) Dsimw501_GD25362(Dsim_GD25362) Dsimw501_GD25363(Dsim_GD25363)

DWI:	6638175 6646352

DYA:	Dyak_GE13887 Dyak_GE13888 Dyak_GE20238 Dyak_GE20239

DGR:	Dgri_GH16129 Dgri_GH19804

DMO:	Dmoj_GI12398 Dmoj_GI20343 Dmoj_GI20347

DAZ:	108612257 108614899 108615720 108615721

DNV:	108650136 108652743 108652744 108653114

DHE:	111592737 111604234 111604271 111604278

DVI:	Dvir_GJ12287 Dvir_GJ22069 Dvir_GJ22071

MDE:	101892521 101897164

AGA:	AgaP_AGAP010695

AAG:

5579662

CQU:	CpipJ_CPIJ011025

AME:

411692

BIM:	100742966 100747691

BTER:

100643858 100645908

SOC:	105196410 105198876 105198878 105200079 105201228 105206101 105206102 105206542 105207163

MPHA:

105833246 105835664 105839655 105840209 105840549

AEC:	105146422 105150634

ACEP:

105617270 105627891 105627892

PBAR:

105429762

HST:	105187097 105190307 105190837

DQU:	106743883 106746442 106746445 106746641 106750997

CFO:	105253415 105257376 112639251

LHU:	105677477 105677950

PGC:	109852988 109861827

OBO:	105282540 105284449

PCF:

106784445

NVI:

100116202

MDL:

103571286

TCA:	103313722 654965 662823 664297

DPA:	109533347 109540565 109545211

NVL:	108557524 108559523 108563110 108566796 108568317

BMOR:

101735457 101743614 101744268 101746391 105841414

DPL:	KGM_202674 KGM_204195 KGM_206871 KGM_209918 KGM_211376

PMAC:

106709812 106709861 106709916 106709917 106709918 106709946 106720222 106721572

PRAP:

110993083 110999618 111001210 111002973 111002974

HAW:	110370836 110370977

TNL:	113495289 113495429 113506913

PXY:	105383403 105392258 105394877 105394879 105394880 105394881 105398220

API:	100160501 100569605 100570059 100571105 100571500 100574502 107884928

DNX:	107162281 107162291 107162292 107162293 107165138 107165310 107168528

AGS:	114119097 114119098 114122945 114122980 114124151 114124152 114124156

CLEC:

106664703 106666873

PHU:	Phum_PHUM336650 Phum_PHUM432430 Phum_PHUM486750

ZNE:

110826459

FCD:	110841943 110851042

DPX:	DAPPUDRAFT_108808 DAPPUDRAFT_214082 DAPPUDRAFT_260977 DAPPUDRAFT_307269 DAPPUDRAFT_324294

TUT:	107359173 107364319 107371600

DPTE:

113794805 113797236 113798159 113799467

HRO:	HELRODRAFT_105761

LGI:	LOTGIDRAFT_214031

PCAN:

112558670 112558671 112573450 112573605 112573626 112573795

CRG:	105317417 105320683 105327951 105342352 105344648 105344649

MYI:	110445441 110445491 110461521 110461559

OBI:

106879253

LAK:	106152865 106152867 106156173 106173959 106173973 106182105

SMM:	Smp_051810

SHX:

MS3_01634

NVE:	NEMVE_v1g231850

EPA:	110238283 110238284

ADF:	107341379 107341401 107341402 107341403 107341404

PDAM:

113684907 113684908

SPIS:

111321466 111321467

HMG:	100198256 100200336 100211332

TAD:	TRIADDRAFT_19695

AQU:

100638269

BRP:

103849945

PVU:	PHAVU_006G213900g

PPER:

18789346

PMUM:

103319091

PAVI:

110750281

MDM:	103428935 103441884

MCHA:

111022155

QSU:

112041044

PPP:

112294502

OLU:	OSTLU_33532

OTA:	OT_ostta02g00200 OT_ostta09g02530

BPG:	Bathy14g02650

MIS:	MICPUN_107425(ELO1) MICPUN_88101

MPP:	MICPUCDRAFT_40609

MBR:	MONBRDRAFT_34287 MONBRDRAFT_34679

SRE:	PTSG_03910 PTSG_05847 PTSG_08487

DDI:	DDB_G0270312 DDB_G0271066

DPP:	DICPUDRAFT_27790 DICPUDRAFT_33776

DFA:

DFA_00445

ACAN:

ACA1_167040

PFA:	PF3D7_0605900

PFD:	PFDG_03954

PFH:	PFHG_01226

PYO:	PY17X_0106200(PY00625)

PBE:	PBANKA_010470

PCY:	PCYB_115050

TGO:	TGME49_242380

PTI:	PHATRDRAFT_9255

FCY:	FRACYDRAFT_177742 FRACYDRAFT_277401

TPS:	THAPSDRAFT_93

AAF:	AURANDRAFT_53701

PIF:	PITG_13178 PITG_16760 PITG_16761

PSOJ:

PHYSODRAFT_352093 PHYSODRAFT_354308

SPAR:

SPRG_08322 SPRG_09463

EHX:	EMIHUDRAFT_351492 EMIHUDRAFT_414244 EMIHUDRAFT_414268

GTT:	GUITHDRAFT_98336

LMA:	LMJF_32_1160

LIF:	LINJ_32_1220

LDO:	LDBPK_321220

LMI:	LMXM_31_1160

LBZ:	LBRM_32_1310

» show all

Reference

PMID:20937905

Authors

Ohno Y, Suto S, Yamanaka M, Mizutani Y, Mitsutake S, Igarashi Y, Sassa T, Kihara A

Title

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.

Journal

Proc Natl Acad Sci U S A 107:18439-44 (2010)
DOI:10.1073/pnas.1005572107

LinkDB

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