KEGG   ORTHOLOGY: K12640
Entry
K12640                      KO                                     
Symbol
CYP85A2, BR6OX2
Name
brassinosteroid 6-oxygenase / brassinolide synthase [EC:1.14.14.179 1.14.14.180]
Pathway
map00905  Brassinosteroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00371  Castasterone biosynthesis, campesterol => castasterone
Reaction
R07450  6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (6alpha-hydroxylating)
R07451  6alpha-hydroxy-castasterone,NADPH---hemoprotein reductase:oxygen 6-oxidoreductase
R07455  6-deoxoteasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (teasterone-forming)
R07457  3-dehydro-6-deoxoteasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (3-dehydroteasterone-forming)
R07458  6-deoxotyphasterol,NADPH---hemoprotein reductase:oxygen oxidoreductase (typhasterol-forming)
R07471  castasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, brassinolide-forming)
R08840  teasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, 7-oxateasterone-forming)
R08841  typhasterol,NADPH---hemoprotein reductase:oxygen oxidoreductase (lactonizing, 7-oxatyphasterol-forming)
R10669  6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (castasterone-forming)
R10682  6-deoxocastasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (brassinolide-forming)
R10683  6-deoxotyphasterol,NADPH---hemoprotein reductase:oxygen oxidoreductase (7-oxatyphasterol-forming)
R10684  6-deoxoteasterone,NADPH---hemoprotein reductase:oxygen oxidoreductase (7-oxateasterone-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00905 Brassinosteroid biosynthesis
    K12640  CYP85A2, BR6OX2; brassinosteroid 6-oxygenase / brassinolide synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K12640  CYP85A2, BR6OX2; brassinosteroid 6-oxygenase / brassinolide synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.179  brassinosteroid 6-oxygenase
     K12640  CYP85A2, BR6OX2; brassinosteroid 6-oxygenase / brassinolide synthase
    1.14.14.180  brassinolide synthase
     K12640  CYP85A2, BR6OX2; brassinosteroid 6-oxygenase / brassinolide synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP85 family
   K12640  CYP85A2, BR6OX2; brassinosteroid 6-oxygenase / brassinolide synthase
Genes
ATH: AT3G30180(BR6OX2)
ALY: 9311596
CRB: 17885676
CSAT: 104710811 104780197 104790595
EUS: EUTSA_v10004156mg
BRP: 103837220 103854484 103875063
BNA: 106349108 106363995 106397123 106400040 106410433
BOE: 106301844 106316572
RSZ: 108807315 108825972 108849348
THJ: 104805522 104822777
Reference
  Authors
Shimada Y, Goda H, Nakamura A, Takatsuto S, Fujioka S, Yoshida S.
  Title
Organ-specific expression of brassinosteroid-biosynthetic genes and distribution of endogenous brassinosteroids in Arabidopsis.
  Journal
Plant Physiol 131:287-97 (2003)
DOI:10.1104/pp.013029
  Sequence
[ath:AT3G30180]
Reference
  Authors
Katsumata T, Hasegawa A, Fujiwara T, Komatsu T, Notomi M, Abe H, Natsume M, Kawaide H
  Title
Arabidopsis CYP85A2 catalyzes lactonization reactions in the biosynthesis of 2-deoxy-7-oxalactone brassinosteroids.
  Journal
Biosci Biotechnol Biochem 72:2110-7 (2008)
DOI:10.1271/bbb.80192
  Sequence
[ath:AT3G30180]
LinkDB

DBGET integrated database retrieval system