KEGG   ORTHOLOGY: K14582
Entry
K14582                      KO                                     
Symbol
nahB, doxE
Name
cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase [EC:1.3.1.29 1.3.1.60]
Pathway
map00624  Polycyclic aromatic hydrocarbon degradation
map00626  Naphthalene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00534  Naphthalene degradation, naphthalene => salicylate
Reaction
R04115  cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase
R06910  cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase
R06931  cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase
R07705  anthracene cis-1,2-dihydrodiol:NAD+ 1,2-oxidoreductase
R09162  cis-4,5-dihydroxy-4,5-dihydropyrene:NAD+ 4,5-oxidoreductase
R09183  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00626 Naphthalene degradation
    K14582  nahB, doxE; cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase
   00624 Polycyclic aromatic hydrocarbon degradation
    K14582  nahB, doxE; cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.29  cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
     K14582  nahB, doxE; cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase
    1.3.1.60  dibenzothiophene dihydrodiol dehydrogenase
     K14582  nahB, doxE; cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K14582
Other DBs
GO: 0018505 0018513
Genes
PPI: ND057(nahB)
PFK: PFAS1_28620
PSC: A458_06715
PSTU: UIB01_22635
PBM: CL52_14620
ALT: ambt_17885
RMN: TK49_07960
BMK: DM80_1445(bphB)
PARB: CJU94_38650
PNA: Pnap_2483
NPP: PP1Y_AT15739
NPN: JI59_24665
SBAR: H5V43_22365(hcaB)
SPHY: CHN51_07000
CNA: AB433_18095
AG: AAA16128(doxE)
 » show all
Reference
PMID:8226631
  Authors
Denome SA, Stanley DC, Olson ES, Young KD
  Title
Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway.
  Journal
J Bacteriol 175:6890-901 (1993)
DOI:10.1128/JB.175.21.6890-6901.1993
  Sequence
[ag:AAA16128]
LinkDB

KEGG   ENZYME: 1.3.1.29
Entry
EC 1.3.1.29                 Enzyme                                 
Name
cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase;
(+)-cis-naphthalene dihydrodiol dehydrogenase;
naphthalene dihydrodiol dehydrogenase;
cis-dihydrodiol naphthalene dehydrogenase;
cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
(1R,2S)-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase
Reaction(IUBMB)
(1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+ [RN:R04115]
Reaction(KEGG)
R04115;
(other) R06910 R06931 R07705 R09162 R09183
Substrate
(1R,2S)-1,2-dihydronaphthalene-1,2-diol [CPD:C04314];
NAD+ [CPD:C00003]
Product
naphthalene-1,2-diol [CPD:C03012];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts, at half the rate, on cis-anthracene dihydrodiol and cis-phenanthrene dihydrodiol.
History
EC 1.3.1.29 created 1976
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec00626  Naphthalene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14582  cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase
Genes
PPI: ND057(nahB)
PFK: PFAS1_28620
PSC: A458_06715
PSTU: UIB01_22635
PBM: CL52_14620
ALT: ambt_17885
RMN: TK49_07960
BMK: DM80_1445(bphB)
PARB: CJU94_38650
PNA: Pnap_2483
NPP: PP1Y_AT15739
NPN: JI59_24665
SBAR: H5V43_22365(hcaB)
SPHY: CHN51_07000
CNA: AB433_18095
 » show all
Reference
1  [PMID:4369091]
  Authors
Patel TR, Gibson DT.
  Title
Purification and propeties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida.
  Journal
J Bacteriol 119:879-88 (1974)
DOI:10.1128/JB.119.3.879-888.1974
Other DBs
ExplorEnz - The Enzyme Database: 1.3.1.29
IUBMB Enzyme Nomenclature: 1.3.1.29
ExPASy - ENZYME nomenclature database: 1.3.1.29
UM-BBD (Biocatalysis/Biodegradation Database): 1.3.1.29
BRENDA, the Enzyme Database: 1.3.1.29
CAS: 53986-49-5
LinkDB

KEGG   REACTION: R06910
Entry
R06910                      Reaction                               
Name
cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase
Definition
cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+ <=> 1,2-Dihydroxy-8-methylnaphthalene + NADH + H+
Equation
C14083 + C00003 <=> C14084 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00891  C14083_C14084
Enzyme
1.3.1.29
Pathway
rn00626  Naphthalene degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.29
     R06910  cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene + NAD+ <=> 1,2-Dihydroxy-8-methylnaphthalene + NADH + H+
Orthology
K14582  cis-1,2-dihydro-1,2-dihydroxynaphthalene/dibenzothiophene dihydrodiol dehydrogenase [EC:1.3.1.29 1.3.1.60]
LinkDB

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