Entry
Name
farnesyl diphosphatase;
FPP phosphatase
Class
Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases
BRITE hierarchy
Sysname
(2E,6E)-farnesyl-diphosphate diphosphohydrolase
Reaction(IUBMB)
(2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesol + diphosphate [RN:
R08697 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme is involved in the biosynthesis of acyclic sesquiterpenoids [1].
History
EC 3.1.7.6 created 2010
Pathway
ec00900 Terpenoid backbone biosynthesis
ec00909 Sesquiterpenoid and triterpenoid biosynthesis
Orthology
K15793 acyclic sesquiterpene synthase
Genes
TDC : 119356231 119356232 119365401 119365402
TAES : 100873133 123041882 123041883 123054327 123190213 123191849
PVIR : 120640652 120683675
» show all
Taxonomy
Reference
Authors
Song L
Title
A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol.
Journal
Reference
Authors
Tsai SC, Gaylor JL.
Title
Testicular sterols. V. Preparation and partial purification of a microsomal prenol pyrophosphate pyrophosphohydrolase.
Journal
J Biol Chem 241:4043-50 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.7.6
ExPASy - ENZYME nomenclature database: 3.1.7.6
BRENDA, the Enzyme Database: 3.1.7.6
LinkDB
All DBs