KEGG   ORTHOLOGY: K18280
Entry
K18280            Tight     KO                                     
Symbol
FTMD
Name
6-hydroxytryprostatin B O-methyltransferase [EC:2.1.1.293]
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00786  Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
Reaction
R10588  S-adenosyl-L-methionine:6-hydroxytryprostatin B O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K18280  FTMD; 6-hydroxytryprostatin B O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.293  6-hydroxytryprostatin B O-methyltransferase
     K18280  FTMD; 6-hydroxytryprostatin B O-methyltransferase
Genes
AFM: AFUA_8G00200
NFI: NFIA_093710
Reference
  Authors
Kato N, Suzuki H, Okumura H, Takahashi S, Osada H
  Title
A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293.
  Journal
Biosci Biotechnol Biochem 77:1061-7 (2013)
DOI:10.1271/bbb.130026
  Sequence
LinkDB

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