KEGG   ORTHOLOGY: K20457
Entry
K20457                      KO                                     

Name
DHFS
Definition
dihydrofolate synthase [EC:6.3.2.12]
Pathway
ko00790  Folate biosynthesis
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K20457  DHFS; dihydrofolate synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     K20457  DHFS; dihydrofolate synthase
Other DBs
RN: R02237
COG: COG0285
GO: 0008841
Genes
ATH: AT5G41480(GLA1)
ALY: 9306705
CRB: 17879364
CSAT: 104719816 104724515 104730143
EUS: EUTSA_v10027718mg
BRP: 103827738
BNA: 106397139 106410800
BOE: 106301878
RSZ: 108837369 108851652
THJ: 104813180
CPAP: 110823533
CIT: 102611256
CIC: CICLE_v10007115mg
TCC: 18605713
GRA: 105765472
GHI: 107942305 107947263
GAB: 108478339
DZI: 111309392
EGR: 104424477
GMX: 100816933
GSJ: 114371141 114384274
PVU: PHAVU_001G060700g
VRA: 106765120
VAR: 108338371
VUN: 114194760
CCAJ: 109795452
MTR: MTR_1g028510 MTR_7g100940
CAM: 101503731
LJA: Lj2g3v3340810.2(Lj2g3v3340810.2) Lj2g3v3340810.3(Lj2g3v3340810.3) Lj2g3v3340810.4(Lj2g3v3340810.4)
ADU: 107495163
AIP: 107605238
LANG: 109354372
FVE: 101295861
RCN: 112182636
PPER: 18785518
PMUM: 103333670
PAVI: 110767141
MDM: 103439847
PXB: 103948060 103958166
ZJU: 107414572
CSV: 101208344
CMO: 103503019
MCHA: 111011557
CMAX: 111483133
CMOS: 111430739
CPEP: 111810923
RCU: 8274389
JCU: 105648365
HBR: 110637511
MESC: 110618018
POP: 18105679
PEU: 105113451
JRE: 109014167
QSU: 111987913 112011275 112015930 112020235
VVI: 100267405
SLY: 101257178
SPEN: 107023886
SOT: 102603442
CANN: 107873434 107875563
NTA: 107764574 107798987
NSY: 104211315
NTO: 104084612
NAU: 109223898
INI: 109193824
SIND: 105166726
HAN: 110905160
LSV: 111888854
CCAV: 112525652
DCR: 108196284
BVG: 104888294
SOE: 110780071
CQI: 110729225
NNU: 104592271
PSOM: 113321187 113340246
OSA: 9266309
OBR: 102706341
BDI: 100844013
ATS: 109780420
SBI: 8066349
ZMA: 100285263(si605087f07a) 103650558
SITA: 101772222
PDA: 103702943
EGU: 105040732
MUS: 104000831
DCT: 110094420
PEQ: 110022275
AOF: 109828889
ATR: 18424396
SMO: SELMODRAFT_428477 SELMODRAFT_90954
PPP: 112278513
CRE: CHLREDRAFT_143847(FPGS1)
VCN: VOLCADRAFT_116089
MNG: MNEG_3751
CSL: COCSUDRAFT_47836
CVR: CHLNCDRAFT_52299
APRO: F751_6837
OLU: OSTLU_13191 OSTLU_29778
OTA: OT_ostta13g01570
BPG: Bathy17g01980
SCE: YKL132C(RMA1) YMR113W(FOL3)
AGO: AGOS_AEL310C
ERC: Ecym_6102
KLA: KLLA0_B12463g
KMX: KLMA_30111(FOL3)
LTH: KLTH0D04664g
VPO: Kpol_297p9
ZRO: ZYRO0G20064g
CGR: CAGL0K03553g
NCS: NCAS_0A04290(NCAS0A04290)
NDI: NDAI_0E02020(NDAI0E02020)
TPF: TPHA_0G02400(TPHA0G02400)
TBL: TBLA_0I00690(TBLA0I00690)
TDL: TDEL_0A02110(TDEL0A02110)
KAF: KAFR_0D02970(KAFR0D02970)
ZMK: HG535_0D02960
PPA: PAS_chr1-4_0009
DHA: DEHA2F21846g
PIC: PICST_47181(FOL3)
PGU: PGUG_00361
SPAA: SPAPADRAFT_63736
LEL: LELG_05479
CAL: CAALFM_C701280CA(CaO19.6908)
CTP: CTRG_04865
COT: CORT_0H00520
CDU: CD36_71120
CTEN: CANTEDRAFT_116748
YLI: YALI0A10032g
CLU: CLUG_05665
CLUS: A9F13_05g02915
CAUR: CJI97_005543
SLB: AWJ20_4428(FOL3)
PKZ: C5L36_0C02990
BNN: FOA43_001666
NCR: NCU01337
NTE: NEUTE1DRAFT115854(NEUTE1DRAFT_115854)
SMP: SMAC_04026
PAN: PODANSg8090
TTT: THITE_2106750
MTM: MYCTH_2300611
CTHR: CTHT_0066900
MGR: MGG_06002
TMN: UCRPA7_3458
SSCK: SPSK_04269
FGR: FGSG_10379
FPU: FPSE_01190
FVR: FVEG_03109
FOX: FOXG_05023
NHE: NECHADRAFT_40672
TRE: TRIREDRAFT_111536
TRR: M419DRAFT_12013
MAW: MAC_04937
MAJ: MAA_03215
CMT: CCM_09601
PLJ: VFPFJ_04470
VAL: VDBG_00628
VDA: VDAG_00241
CFJ: CFIO01_02343
SAPO: SAPIO_CDS10795
ELA: UCREL1_6745
PFY: PFICI_13397
SSL: SS1G_03715
BFU: BCIN_04g00610
MBE: MBM_05109
PSCO: LY89DRAFT_722384
GLZ: GLAREA_05318
ANI: AN4384.2
AFM: AFUA_4G06740
ACT: ACLA_045970
NFI: NFIA_109490
AOR: AO090023000912
ANG: ANI_1_258184(An04g01120)
AFV: AFLA_113210
PCS: Pc22g17760
PDP: PDIP_13400
TMF: PMAA_027940
TRG: TRUGW13939_03483
CIM: CIMG_04102
CPW: CPC735_003030
PBL: PAAG_07676
PBN: PADG_04506
URE: UREG_05543
ABE: ARB_02693
TVE: TRV_05429
AJE: HCAG_03334
BGH: BDBG_04871
PNO: SNOG_05335
PTE: PTT_11148
BZE: COCCADRAFT_104434
BSC: COCSADRAFT_99608
BOR: COCMIDRAFT_1268
AALT: CC77DRAFT_1063596
ZTR: MYCGRDRAFT_64294
PFJ: MYCFIDRAFT_84150
BCOM: BAUCODRAFT_68829
NPA: UCRNP2_5739
TML: GSTUM_00003931001
SPO: SPAC227.09
CNE: CNH02620
CNB: CNBL2660
CGI: CGB_L3300C
TMS: TREMEDRAFT_31421
TVS: TRAVEDRAFT_176317
DSQ: DICSQDRAFT_112243
PCO: PHACADRAFT_177373
SHS: STEHIDRAFT_152355 STEHIDRAFT_98452
HIR: HETIRDRAFT_65092
PSQ: PUNSTDRAFT_34460
ADL: AURDEDRAFT_115719
FME: FOMMEDRAFT_105190
GTR: GLOTRDRAFT_81701
LBC: LACBIDRAFT_152448
MRR: Moror_12402
CCI: CC1G_04850
SCM: SCHCODRAFT_74357
ABP: AGABI1DRAFT109678(AGABI1DRAFT_109678)
ABV: AGABI2DRAFT187126(AGABI2DRAFT_187126)
CPUT: CONPUDRAFT_103921
SLA: SERLADRAFT_470633
WSE: WALSEDRAFT_54229
WIC: J056_001491
MGL: MGL_2156
MRT: MRET_0353
MSYM: MSY001_1891
MLR: MELLADRAFT_116823
EHE: EHEL_050070
MALV: MALV_00140
 » show all
Reference
  Authors
Ravanel S, Cherest H, Jabrin S, Grunwald D, Surdin-Kerjan Y, Douce R, Rebeille F
  Title
Tetrahydrofolate biosynthesis in plants: molecular and functional characterization of dihydrofolate synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana.
  Journal
Proc Natl Acad Sci U S A 98:15360-5 (2001)
DOI:10.1073/pnas.261585098
  Sequence
[ath:AT5G41480]
Reference
  Authors
Cherest H, Thomas D, Surdin-Kerjan Y
  Title
Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance of intact mitochondrial genome in Saccharomyces cerevisiae.
  Journal
J Biol Chem 275:14056-63 (2000)
DOI:10.1074/jbc.275.19.14056
  Sequence
[sce:YMR113W]
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