KEGG   REACTION: R13169
Entry
R13169                      Reaction                               
Definition
Sialyl-3-paragloboside + UDP-N-acetyl-D-galactosamine <=> IV4GalNAcb-SPG ganglioside + UDP
Equation
G00062 + G10611 <=> G00883 + G10619
Comment
UDP-GalNAc beta1,4-N-acetylgalactosaminyltransferase
Enzyme
2.4.1.-
Pathway
rn00601  Glycosphingolipid biosynthesis - lacto and neolacto series
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-
     R13169  Sialyl-3-paragloboside + UDP-N-acetyl-D-galactosamine <=> IV4GalNAcb-SPG ganglioside + UDP
Orthology
K09655  beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-]
Reference
1  [PMID:36287346]
  Authors
Duca M, Malagolini N, Dall'Olio F.
  Title
The story of the Sd(a) antigen and of its cognate enzyme B4GALNT2: What is new?
  Journal
Glycoconj J 40:123-133 (2023)
DOI:10.1007/s10719-022-10089-1
Reference
2  [PMID:12678917]
  Authors
Montiel MD, Krzewinski-Recchi MA, Delannoy P, Harduin-Lepers A
  Title
Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain.
  Journal
Biochem J 373:369-79 (2003)
DOI:10.1042/BJ20021892
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