| Entry |
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| Symbol |
tylMII
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| Name |
(KEGG) tylactone mycaminosyltransferase (EC:2.4.1.316)
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| KO |
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| Taxonomy |
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| Lineage |
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces |
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| Organism |
Streptomyces fradiae
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| Module |
| 1906_M00773 | Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin |
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| AA seq |
452 aa
MRRALDDRRRGPHGPEGKPPMRVLLTCIAHNTHYYNLVPVAWALRAAGHEVRVAAQPALT
DTITASGLTAVPVGGNESVLEFVTEIGGDPGPYQRGMDFAETCGEPLSYEHALGQQTAMS
ALCFAPFNCDSTIDDMVALARSWRPDLVLWEPFTYAGPIAAHACGAAHARLLWGPDVILN
ARAQFRRLAAGQPEERREDPVAEWLGWTLERHGLTAERETVEELIGGQWTLDPTAESLRL
PAAGRVVPFRFVPYNGRSVLPDWLLRKPGRPRVCFTLGVSARETYGRDAVPFHELLAGLG
DLDAEIVATLDPGQLSGAGEVPRNVRAVDFVPMDALLPTCSAVVHHGGAGTCFTATLNGL
PQIVVAALWDAPLKGAQLAEAGAGVSIAPEKLDAATLRAGVVRALEDEDMRRSAGLLRAE
MLAEPTPAGLVPQLERLTALHRNGRSRSAPER |
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| Reference |
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| Authors |
Gandecha AR, Large SL, Cundliffe E |
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| Title |
Analysis of four tylosin biosynthetic genes from the tylLM region of the Streptomyces fradiae genome. |
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| Journal |
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| Reference |
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| Authors |
Melancon CE 3rd, Takahashi H, Liu HW |
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| Title |
Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient glycosyltransfer in macrolide antibiotic biosynthesis. |
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| Journal |
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