Alloactinosynnema sp. L-07: CRK59650
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Entry
CRK59650 CDS
T04489
Name
(GenBank) Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex / 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
alo
Alloactinosynnema sp. L-07
Pathway
alo00020
Citrate cycle (TCA cycle)
alo00630
Glyoxylate and dicarboxylate metabolism
alo00785
Lipoic acid metabolism
alo01100
Metabolic pathways
alo01110
Biosynthesis of secondary metabolites
alo01120
Microbial metabolism in diverse environments
alo01200
Carbon metabolism
alo01210
2-Oxocarboxylic acid metabolism
Module
alo_M00009
Citrate cycle (TCA cycle, Krebs cycle)
alo_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
alo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CRK59650
00630 Glyoxylate and dicarboxylate metabolism
CRK59650
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CRK59650
Enzymes [BR:
alo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CRK59650
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CRK59650
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CRK59650
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CRK59650
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
CRK59650
UniProt:
A0A0H5D4X1
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All DBs
Position
I:4843312..4847016
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AA seq
1234 aa
AA seq
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MSSSSPASQFGANEWLVEEMYEQFLADPSSVDPAWHDFFADYKPTPRAASQGAAQAKSAG
SDSGTATPPAASTTTATKPPQQPPAAPKPAQAVPSGNGQPAATPAAKPAAVAAKPAGQGE
ERKPLRGAAAAIAKNMNASLTLPTATSVRAVPAKLLADNRIVINNHLKRTRGGKVSFTHL
IGYAMVRALEAYPNMNRHYAEDGGKTFAVTPEHVNLGLAIDLPGKDGSRNLVVAAIKGCE
GMTFQQFWQAYEDLIRKARTGALTADDFAGTTISLTNPGGIGTNHSVPRLSVGQGTILGV
GAMEYPAPFQGAAETNLIEMGISKIITLTSTYDHRIIQGAESGEFLGRIHKLLLGEDGFY
DDIFTSLRIPYEPIRWTSDLAEGPVDKTARVIGLIDAYRTRGHLMADTDPLNYRQRKHED
LDVRSHGLTLWDLDREFPVGGFAGKERMKLRDVLGVLRDSYCRTVGVEYTYILDPAERRW
IQDRVEGAHEKPPAAVQKYVLSKLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDTVL
DKAAEYELDEVVIGMPHRGRLNVLANIVGKPISQIFQEFEGNLDPGQAHGSGDVKYHLGA
EGKYFRMFGDGETKVSLTANPSHLETVDPVLEGIVRAKQDLLNKGDASGGFSVLPVALHG
DAAFAGQGVVAETLNLALLRGYRTGGTVHVIINNQVGFTTAPEHSRSSQYATDVAKMIQA
PVFHVNGDDPEACYWVARLAMDYRQTFNKDVVIDMVCYRRRGHNEGDDPSMTQPGMYDII
DTKRSVRKGYTEALIGRGDISVEEAEKALRDFSSQLEHVFNEVRELEKHPIVASPSVESE
QQVPAKLATGVSAAVLERIADAHTDLPDGFSPHPRVKPVLDRRAKMSREGDIDWAYGELL
AFGSLNIEGRTVRLAGQDSRRGTFTQRHAAIIDRKSGKEYLPLQNLSEDQGKFMVYDSAL
SEYAALGFEYGYSVANPDALVLWEAQFGDFVNGAQSVIDEYIASSEAKWGQCSDVVVLLP
HGHEGQGPDHTSGRIERWLQLCAEGSMTVSVPSTPANYFHLLRRHALDGVQRPLVVFTPK
SMLRNKAATSPVADFLTGTRFEKVIDDPTAPDPAGVTKLLFVSGKLYYELAAEQAKRDIK
DTAVVRVEQLYPMPLERLTAIFKKYPNAADYRWVQEEPANQGSWPFYGLNLPEALPEHVT
KLTRVSRRPMSAPSAGSSKVHELEQRALIEKAFQ
NT seq
3705 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagtcccgcgtcacagttcggtgcgaacgagtggctcgtcgaagagatg
tatgagcagttcctcgcggatccgtcttcggtagaccccgcgtggcacgacttcttcgcc
gactacaagccgacaccgcgcgccgccagccaaggtgccgctcaggccaagagtgcgggg
agtgacagcgggacggcgacgccgcccgccgcgtcgacgaccaccgcgaccaagccgccg
cagcagccgcccgccgcgcccaagcccgcgcaggccgtgccatcgggcaacggccagccc
gccgcgacgcccgcggccaagcccgccgccgtggcggccaagcccgctgggcagggcgag
gagcgcaagccgctgcgcggggccgccgccgcgatcgcgaagaacatgaacgcgtcgctg
acgctgccgaccgcgaccagcgtgcgcgcggtgcccgcgaagctgctcgcggacaaccgc
atcgtgatcaacaaccacctcaagcggacccgcggtgggaaggtctccttcacccacctg
atcggctacgcgatggtgcgcgcccttgaggcgtacccgaacatgaaccggcactacgcc
gaggacggcggaaagaccttcgccgtcacccccgagcacgtcaacctcggcctggcgatc
gacctgcccggcaaggacggctcgcgcaatctggtcgtcgcggcgatcaagggctgcgag
ggcatgaccttccagcagttctggcaggcctacgaggacctgatccgcaaggcccgcacc
ggagcgctcaccgcggacgacttcgcgggcaccacgatctcgctgaccaaccccggcggc
atcggcaccaaccactcggtgccccggctgtcggtcggccagggcacgatcctcggcgtc
ggcgcgatggagtaccccgcgccgttccagggtgccgccgagacgaacctcatcgagatg
ggcatcagcaagatcatcacgctgacgtccacctacgaccaccgcatcatccagggcgcg
gagtccggcgagttcctcggccgcatccacaagctgctgctgggcgaggacggcttctac
gacgacatcttcacgtcgctgcggatcccgtacgagccgatccgctggacgtcggacctg
gccgaggggccggtcgacaagaccgcccgcgtcatcggcctgatcgacgcctatcgcacc
cgcggtcacctgatggccgacaccgacccgctgaactaccgccagcgcaagcacgaggac
ctcgacgtccggtcgcacggcctgaccctgtgggacctcgaccgcgagttccccgtcggc
ggcttcgcgggcaaggagcggatgaagctgcgcgacgtcctcggcgtgctgcgcgactcg
tactgcagaaccgtcggcgtcgagtacacctacatcctcgacccggccgagcgccgctgg
atccaggaccgcgtcgagggcgcgcacgagaagcccccggcggccgtgcagaagtacgtg
ctgtcgaagctcaacgccgccgaggcgttcgagaccttcctgcagaccaagtacgtcggc
cagaagcggttctcgctcgaaggcggcgagtcggtcatcccgctgctggacacggtgctg
gacaaggccgccgagtacgagctcgacgaggtcgtcatcggcatgccgcaccgcggccgc
ctcaacgtgctcgccaacatcgtcggcaagccgatctcccagatcttccaggagttcgag
ggcaaccttgaccccggccaggcgcacggctccggcgacgtgaagtaccacctcggcgcc
gagggcaagtacttccggatgttcggcgacggcgagaccaaggtgtcgctgacggccaac
ccgtcgcacctggagaccgtcgacccggtcctggagggcatcgtccgggccaagcaggac
ctgctcaacaagggcgacgccagcggtggcttctcggtcctgccggtcgccctgcacggc
gacgccgcgttcgcgggtcagggcgtggtcgccgagaccctgaacctggcgctgctgcgc
ggctaccgcaccggcggcaccgtgcacgtgatcatcaacaaccaggtcggcttcaccacc
gccccggagcactcgcggtcgagccagtacgccaccgacgtcgccaagatgatccaggcg
ccggtgttccacgtgaacggcgacgacccggaggcctgctactgggtggcgcgactggcg
atggactaccggcagacgttcaacaaggacgtcgtgatcgacatggtctgctaccgccgc
cgcggccacaacgagggcgacgacccttcgatgacccagcccggcatgtacgacatcatc
gacaccaagcggtcggtgcgtaagggctacaccgaggcgctcatcggccgcggcgacatc
tccgtcgaggaggccgagaaggcgctgcgcgacttctccagccagttggagcacgtcttc
aacgaggtccgcgagctggagaagcacccgatcgtggccagcccgtcggtggagtccgag
cagcaggtgcccgccaagctggccaccggcgtgagcgccgcggtgctggagcgcatcgcc
gacgcgcacaccgacctgcccgacggcttcagcccgcacccgcgggtcaagccggtgctc
gaccgccgcgccaagatgtcccgcgaaggcgacatcgactgggcctacggcgagctgctg
gcgttcggctccctcaacatcgagggccgcacggtgcgcctggctggccaggactcgcgc
cgcggcacgttcacccagcggcacgcggcgatcatcgaccgcaagtccggcaaggaatac
ctgccgctgcagaacctgtccgaggaccagggcaagttcatggtctacgactcggcgctg
tcggagtacgcggcactgggcttcgagtacggctactcagtggccaacccggacgcgctg
gtgctgtgggaggcgcagttcggcgacttcgtcaacggcgcccagtcggtgatcgacgag
tacatcgcctccagcgaggccaagtggggccagtgctccgacgtggtcgtgctgctgccg
cacggccacgagggccagggccccgaccacacctcgggccgcatcgagcgctggctgcag
ctgtgcgccgagggctcgatgacggtgtcggtgccgtcgaccccggcgaactacttccac
ctgctgcgccgccacgccctcgacggcgtgcagcgtccgctggtggtgttcacgccgaag
tcgatgctgcgcaacaaggccgcgaccagccccgtcgcggacttcctcaccggcacccgg
ttcgagaaggtcatcgatgacccgaccgcgccggacccggccggggtgaccaagctgctg
ttcgtctccggcaagctctactacgagctggccgccgaacaggccaagcgcgacatcaag
gacaccgcggtcgtgcgcgtcgagcagctctacccgatgcccctcgaacggctcacggcg
atcttcaagaagtacccgaacgccgcggactaccgctgggtccaggaagagcccgccaac
cagggctcgtggccgttctacggcctgaacctcccagaggcgctgcccgagcacgtcacc
aagctcacccgcgtctcccgccgtccgatgtcggcgccgtcggccggatcgagcaaggtc
cacgaactcgaacagcgcgcgctgatcgagaaggcgttccagtaa
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